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St. Jude discovery offers new avenues to understanding an aggressive form of leukemia
Researchers at St. Jude Childrenˇ¦s Research Hospital have discovered evidence that a series of genetic mutations work together to initiate most cases of an aggressive and often-fatal form of acute lymphoblastic leukemia (ALL).   view more (2008-04-15)

Gene Variant Increases Breast Cancer Risk
In roughly five to ten percent of breast cancer cases there is a family history of breast cancer- i.e., hereditary and, thus, genetic factors play a role here. Alterations in the genes known as BRCAI and BRCAII are a major cause of familial breast cancer - these are responsible for roughly 25... view more (2008-03-17)

Women testing negative for familial breast cancer gene still at increased risk
Women testing negative for the two inherited breast cancer genes are still at increased risk of developing the disease, suggests research published ahead of print in the Journal of Medical Genetics.   view more (2006-10-31)

Gene-expression profiling of the effects of liver toxins
Gene-expression data from liver tissue or whole blood can be used to classify histopathologic differences in the effects of hepatotoxins. It is hoped that these findings, published in BioMed Central's open access journal, Genome Biology, will lead to a more precise way of defining the potential... view more (2008-06-20)

Inherited melanoma risk: What you do know does help you
When people know the results of genetic tests confirming they have inherited an increased risk of developing melanoma, they follow skin cancer screening recommendations more proactively-much like those who have already been diagnosed with the potentially deadly disease.   view more (2008-06-18)

Gene elevating breast cancer risk also causes prostate cancer
Cancer is a complex and common disease caused by a combination of both genetic and environmental factors. An inherited predisposition seems to be involved in at least 5-10 per cent of all cases of breast cancer.   view more (2007-02-09)

NYU algorithm enhances ability to detect cancer genes
Researchers at New York University's Courant Institute of Mathematical Sciences have developed a new algorithm that enhances the ability to detect a cancer gene, and have applied their algorithm to map the set of tumor-suppressor genes involved in lung cancer.   view more (2006-05-10)

New genetic techniques to combat lung cancer
New results on genetic techniques that are helping doctors diagnose and treat lung cancer were released today at the 1st European Lung Cancer Conference jointly organized by the European Society for Medical Oncology (ESMO) and the International Association for the Study of Lung Cancer (IASLC) in... view more (2008-04-28)

Scientists Uncover Rules for Gene Amplification
Gene amplification plays an important role in causing cancers via activation of oncogenes.   view more (2006-06-30)

UVA studies potential target for skin cancer treatment
When normal skin cells become a melanoma tumor, they sometimes turn on genes not usually found in the skin.   view more (2006-10-04)

Prevent prostate cancer with antioxidants? Gene pathway may reveal more clues
Scientists from Maryland and New Jersey have identified a molecular pathway in mice that makes prostate cells vulnerable to cancer-causing oxygen damage. The pathway, which is also involved in human prostate cancer, may help determine how and whether antioxidants, such as certain vitamins or their... view more (2005-09-16)

Gene expression in labor; and more — press release from PLoS Medicine
A Research Article, Perspective and e-Letter all published today discuss the use of microarrays to discover genes involved in childbirth. The three papers highlight the complexity of such gene expression analyses but also how crucial it is to make original data available for reanalysis.   view more (2006-06-13)

Gene therapy protocol at UCSD activates immune system in patients with leukemia
A research team at the Moores Cancer Center at University of California, San Diego (UCSD) reports that patients with chronic lymphocytic leukemia (CLL) who were treated with a gene therapy protocol began making antibodies that reacted against their own leukemia cells.   view more (2008-02-12)

Profiling of cancer genes may lead to better and earlier detection
A research team at UT Southwestern Medical Center has for the first time identified several genes whose expression is lost in four of the most common solid human cancers - lung, breast, prostate and colon cancer.   view more (2006-12-27)

A tumor suppressor that promotes cancer cell growth?
Researchers have shown that the tumor suppressor gene H-REV107-1 may actually stimulate tumor progression in some non-small cell lung carcinomas.   view more (2006-10-09)

New technique detects early metastasis of breast cancer
In the U.S., a novel technology soon may be available to detect the spread, or metastasis, of breast cancer earlier than now possible, according to research presented at the first international meeting on Molecular Diagnostics in Cancer Therapeutic Development.   view more (2006-09-14)

Portuguese distinguished in article about stomach cancer
Three Portuguese researchers are co-authors of a scientific article about hereditary stomach cancer, published in the medical journal "New England Journal of Medicine" and recently awarded the Benjamin Castleman 2002 Award. Attributed by the International Academy of Pathology, the prize... view more (2002-06-18)

Iowa State researcher studies gene families to explore diversity and evolution
Theoretical biologist Stephen Proulx studies gene families to explore how genomes become diverse and evolve.   view more (2006-08-01)

DNA test shows promise for identifying patients with colorectal cancer (p 1283)
Testing for DNA changes in stools might provide a new, accurate, and less invasive way to screen patients for colorectal cancer, conclude the authors of a research letter in this week's issue of THE LANCET. Colorectal cancer is one of the most common cancers in the industrialised world, and early... view more (2004-04-14)

Salt of the Earth
A yeast gene responsible for salt tolerance has successfully been used to grow tobacco in a salty environment lethal to most plants. Dr Janey Henderson and Professor Phil Harris from Coventry University inserted the halotolerance gene HAL1 from yeast into a tobacco plant. HAL1 has previously been... view more (2001-04-04)

New clues for treatment of liver cancer
By generating tumors in laboratory mice that mimic human liver cancer and by comparing the DNA of mouse and human tumors, researchers at Cold Spring Harbor Laboratory have identified two genes that are likely to play a role in the third leading cause of human cancer deaths.   view more (2006-06-29)

Study details regulation of vital tumor suppressor gene p53
So vital is the p53 tumor suppressor gene in controlling cancer that its dysfunction is linked to more than half of human cancers.   view more (2007-09-06)

University of Leicester First for New Technology
A research team at the University of Leicester has won funding for projects examining 60,000 gene interactions simultaneously. Announcing two awards Professor Joe Lunec, Head of the Division of Chemical Pathology, said that an award of £300,000 from the Food Standards Agency will establish a... view more (2000-08-04)

Jefferson scientists explain cancer cell metabolism changes
Scientists at Jefferson Medical College and the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia have found how a gene can dim the power production in the cell and in turn scale up its cancer-producing activities.   view more (2006-08-29)

Cancer researchers describe gene that halts spread of aggressive childhood cancer
A team of cancer researchers has shown that a gene commonly lost during neuroblastoma tumor formation, one of the most aggressive cancers in babies and children, is in fact a "metastasis suppressor" gene.   view more (2006-01-05)
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