Cancer Gene Current Events | Cancer Gene News | 11
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Intravenous nanoparticle gene therapy shows activity in stage IV lung cancer
A cancer-suppressing gene has been successfully delivered into the tumors of stage 4 lung cancer patients via an intravenously administered lipid nanoparticle in a phase I clinical trial at The University of Texas M. D. Anderson Cancer Center. view more (2007-04-18)
Researchers identify gene set linked to breast cancer's spread to lungs
In a potential advance for the treatment of aggressive breast cancer, scientists at Memorial Sloan-Kettering Cancer Center (MSKCC) have identified a set of genes in breast tumors that appear to predict if the disease will spread to the lungs and, once there, how virulent it will become. view more (2005-07-28)
Breast cancer risk amplified by additional genes in combo with BRCA mutation
Many women with a faulty breast cancer gene could be at greater risk of the disease due to extra risk-amplifying genes, according to research published this month in the American Journal of Human Genetics. view more (2008-04-17)
Resistance to chemotherapy in lung cancer, optimizing flu vaccination strategies
Lung cancer is the most common cause of cancer-related death worldwide, in part because these tumors often are or become resistant to chemotherapy. view more (2006-10-03)
Unique role for blood formation gene identified
All blood cell production in adults depends on the steady work of a vital gene that if lost results in early bone marrow failure, Dartmouth Medical School cancer geneticists have found. view more (2007-09-13)
African American lung cancer patients may have different response to new cancer-fighting drugs
Clinical research out of University Hospitals Case Medical Center has found that African Americans with a common form of lung cancer have a lower frequency of drug-sensitizing genetic mutations, which may impact response to new cancer-fighting drugs. view more (2009-10-08)
Researchers Identify Specific Lung Cancer Susceptibility Gene
University of Cincinnati (UC) cancer cell biologists have identified a distinct gene linked to increased lung cancer susceptibility and development. view more (2009-04-16)
Which is promising as therapeutic targets in patients with biliary tract cancer? EGFR or HER2?
The epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2) are involved in the carcinogenesis of many malignancies. view more (2009-10-16)
Researchers Identify Role of Gene in Tumor Development, Growth and Progression
Virginia Commonwealth University Massey Cancer Center and VCU Institute of Molecular Medicine researchers have identified a gene that may play a pivotal role in two processes that are essential for tumor development, growth and progression to metastasis. view more (2009-11-23)
Research reveals molecular pathway behind invasive prostate cancers
University of Cincinnati (UC) cancer and cell biologists have identified a new molecular pathway key to the development of invasive prostate cancers. view more (2009-05-19)
Selenium may prevent high risk-bladder cancer
A study published in the December issue of Cancer Prevention Research, a journal of the American Association for Cancer Research, suggests that selenium, a trace mineral found in grains, nuts and meats, may aid in the prevention of high-risk bladder cancer. view more (2008-12-08)
Nursing study concludes few Ontario women with invasive ovarian cancer referred for genetic testing of breast cancer genes
An Ontario study of 491 women with invasive ovarian cancer found only a small proportion, 19%, were referred for genetic testing of BRCA1 and BRCA2, the breast cancer genes, which means family members are not informed of their cancer risk. view more (2008-12-05)
Traditional herbal medicine kills pancreatic cancer cells, Jefferson researchers report
An herb used in traditional medicine by many Middle Eastern countries may help in the fight against pancreatic cancer, one of the most difficult cancers to treat. view more (2008-05-19)
Study shows liver an excellent target for cancer gene therapy using viral vectors
A featured paper in the February 14 issue of Nature Cancer Gene Therapy demonstrates that cancer cells in the liver are excellent targets for gene therapy using adenoviral vectors, based upon a fundamental new understanding of the differences between cancerous and normal liver cells. view more (2007-02-15)
Breast cancer risk varies significantly among BRCA1 and BRCA2 carriers
There is a broad variation in the risk of developing breast cancer among people who carry the BRCA1 and BRCA2 gene mutation, according to a study in the January 9/16 issue of JAMA. view more (2008-01-09)
In lung cancer, silencing one crucial gene disrupts normal functioning of genome
While examining patterns of DNA modification in lung cancer, a team of international researchers has discovered what they say is a surprising new mechanism. view more (2009-01-05)
Jefferson Scientists Identify Gene Mutation Potentially Involved in Breast Cancer Initiation
Researchers at Jefferson Medical College and the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia and at the Albert Einstein College of Medicine in New York have found evidence suggesting that a mutation in a gene that normally helps block the formation of breast tumors could play a role in the initiation of a major form of... view more... (2006-06-01)
Genes signal late-stage laryngeal cancer, poorer outcome
Researchers at Henry Ford Hospital have identified tumor-suppressing genes that may provide a more accurate diagnosis of disease stage and survival for laryngeal cancer patients than current standards. view more (2009-10-08)
Inventory of Genes
Scientists at DKFZ screen fruit fly genome for cancer-relevant genes Dr. Michael Boutros of the Deutsches Krebsforschungszentrum (German Cancer Research Center, DKFZ) and an international team of collaborators have been the first to screen an almost complete genome for genes that could play a role in cancer. The results have been published in the... view more... (2004-02-09)
Stabilizing cancer-fighting p53 can also shield a metastasis-promoter
Efforts to protect the tumor-suppressor p53 could just as easily shelter a mutant version of the protein, causing cancer cells to thrive and spread rather than die, according to research by scientists at The University of Texas M. D. Anderson Cancer Center reported in the current issue of the journal Genes and Development. view more (2008-05-23)
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