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UI Researchers Studying Novel Therapy For Prostate Cancer
A team of University of Iowa Health Care researchers has launched an important clinical trial of a novel therapeutic that may eventually lead to new treatments for men diagnosed with prostate cancer.   view more (2006-10-16)

Protein Sequences: Not So Predictable After All
Scientists have believed for decades that the sequencing of the human genome would automatically yield the sequences of proteins, the functional products of genes, and thus lead to the unraveling of the mechanisms behind human cell biology and disease. However, a paper published in Science today by... view more (2004-03-01)

Columbia scientists develop cancer terminator viruses
Researchers at Columbia University Medical Center continue to make strides in their work to develop the next generation of effective viral-based therapies for cancer.   view more (2005-09-21)

First Parkinson's Gene Therapy Patient Passes One Year
The first ever patient to have undergone gene therapy for Parkinson's appears to have come through phase I without a hitch, suggesting that the therapy is safe and effective, reports Marina Murphy in Chemistry & Industry.   view more (2004-09-02)

Scientists Find Missing Link to Understand How Plants Make Vitamin C
Vitamin C is possibly the most important small molecule whose biosynthetic pathway remained a mystery. That is until now.   view more (2007-04-30)

Gene variation may elevate risk of liver tumor in patients with cirrhosis
A particular gene variation appears to significantly increase the risk that individuals with cirrhosis of the liver will go on to develop hepatocellular carcinoma (HCC), a liver tumor that is the third leading cause of cancer death.   view more (2008-01-02)

Protein amplification in melanoma is possible drug target
Researchers have pinpointed specific gene and protein over-production in metastatic melanoma, pointing the way to a possible new drug target, according to a study published in Nature July 7.   view more (2005-07-11)

Ireland Cancer Center researcher lays out benefits of aspirin to prevent colon cancer
A colon cancer researcher at the Ireland Cancer Center of University Hospitals Case Medical Center (UHCMC) has laid out the roadmap for how medical science should employ aspirin and new aspirin-like drugs for use in preventing colon cancer in certain high-risk individuals.   view more (2007-05-24)

Ability to track stem cells in tumors could advance cancer treatments
Using noninvasive molecular imaging technology, a method has been developed to track the location and activity of mesenchymal stem cells (MSCs) in the tumors of living organisms.   view more (2008-06-17)

PROSTATE CANCER SERIES (p 859)
A four-week series about prostate cancer-the third most common cancer in men worldwide, and the leading male cancer in Europe and North America-begins in this week's issue of THE LANCET. The first article, by Henrik Grönberg of Umea University, Sweden, assesses the epidemiology of prostate... view more (2003-03-05)

Researchers identify promising gene target for neuroblastoma therapy
Researchers at Dana-Farber Cancer Institute have identified a set of previously unknown mutations in a single gene in 8 percent of neuroblastomas, tumors of the nervous system that occur in young children and account for approximately 15 percent of all childhood cancer deaths.   view more (2008-10-16)

Marine moss reveals clues to anticancer compound
An Oregon Health & Science University researcher believes the discovery of a gene cluster from a bacterium that protects a moss-like marine invertebrate from predators may be the first step toward engineering cancer-fighting drugs.   view more (2007-03-12)

Dardarina, the Basque gene for Parkinson's
Research began when doctors discovered that various members of the same family had Parkinson's. There are many kinds of Parkinson's and some are hereditary. Now, a group of scientists have identified the gene which produces the hereditary Park8 variant of Parkinson's in four Basque families and... view more (2004-11-04)

Polymers are promising tools for gene therapy
New methods are being developed to cure illnesses with the aid of gene therapy. Polymer technology provides new and versatile possibilities for administering gene doses. "Polymers are used to pack the gene to be transferred into particles of the size of a ten thousandth of a millimetre. These... view more (2002-04-24)

Genetic insights may explain retinal growth, eye cancer
Investigators at St. Jude Children's Research Hospital have discovered the role of several key genes in the development of the retina, and in the process have taken a significant step toward understanding how to prevent or cure the potentially deadly eye cancer retinoblastoma.   view more (2006-05-09)

Blocking protein kills prostate cancer cells, inhibits tumor growth, Jefferson scientists find
Researchers at Jefferson's Kimmel Cancer Center in Philadelphia have shown that they can effectively kill prostate cancer cells in both the laboratory and in experimental animal models by blocking a signaling protein that is key to the cancer's growth.   view more (2008-02-28)

Liver cancer marker could yield blood test for early detection
In the face of an emerging liver cancer crisis in Asia, researchers at the Chinese University of Hong Kong have developed a test that could help millions.   view more (2007-09-18)

Bats add their voice to the FOXP2 story
When it comes to the FOXP2 gene, humans have had most to shout about. Discoveries that mutations in this gene lead to speech defects and that the gene underwent changes around the time language evolved both implicate FOXP2 in the evolution of human language.   view more (2007-09-19)

Researchers find better prostate cancer indicators
Researchers at Mayo Clinic have narrowed the search for effective prostate cancer biomarkers (genetic variations that point to a specific disease or condition), identifying changes in the expression of genes of the whole genome closely correlated to prostate cancer development and progression.   view more (2006-03-28)

Cancer scientists create 'human' leukemia process to map how disease begins, progresses
Cancer researchers led by Dr. John Dick at Ontario Cancer Institute (OCI) have developed a method to convert normal human blood cells into "human" leukemia stem cells.   view more (2007-04-27)

Bits of 'junk' RNA aid master tumor-suppressor gene
Little-known bits of RNA help master tumor-suppressor gene do its job, U-M cancer researchers find. Three micro RNA genes appear to be key partners of protective gene p53; their loss is linked to common type of lung cancer.   view more (2007-08-24)

Gene mutation improves leukemia drug's effect
Gene mutations that make cells cancerous can sometimes also make them more sensitive to chemotherapy. A new study led by cancer researchers at Ohio State University shows that a mutation present in some cases of acute leukemia makes the disease more susceptible to high doses of a particular... view more (2008-06-18)

True cancer-causing genes revealed by new technique, say Stanford researchers
Often cancer research goes like this: study cancerous cells in a lab dish, find mutations that appear in many of the samples, develop drugs to target proteins made by the mutated genes, and voila, new chemotherapy drugs are born. Or at least that's the hope.   view more (2005-06-13)

'Signature' of chromosome instability predicts cancer outcomes
Microscopic examination of tumor specimens cannot always predict a cancer's aggressiveness, leading to increased interest in molecular approaches to diagnosis.   view more (2006-08-21)

In 'Spontaneous' Liver Cancer, Researcher Sees a Cure
Adding more good news to last week's announcement that Nexavar® (sorafenib) may be the first effective treatment for advanced liver cancer, researchers at the Lombardi Comprehensive Cancer Center at Georgetown University have uncovered a new molecular mechanism that may... view more (2007-06-20)
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