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Dana Farber and 454 life sciences announce breakthrough in DNA sequencing for cancer research
454 Life Sciences Corporation, a majority-owned subsidiary of CuraGen Corporation (Nasdaq: CRGN), in collaboration with scientists at Dana Farber Cancer Center and Broad Institute, today reported a new method for the detection of cancer gene mutations present at extremely low levels.   view more (2006-06-26)

A classic method for modeling skin cancer is featured in Cold Spring Harbor Protocols
Skin cancer is the most prevalent form of human cancer in the United States, according to the Centers for Disease Control.   view more (2007-09-05)

Discovery in 'Bubble Boy' disease gene therapy
Scientists at St. Jude Children's Research Hospital have developed a mouse model of a severe disease of the immune system that helps explain why gene therapy used to treat children with this disease at an institution in Europe caused some of them to develop leukemia.   view more (2006-08-02)

New technique kills cancer virus without harming healthy cells
Major breakthrough could lead to successful treatment of viral cancers, without side-effects. Yorkshire Cancer Research funded researchers at the University of York have made a major cancer breakthrough. Using a new technique called RNA interference, they have successfully killed human cervical... view more (2002-09-03)

Lung cancer screening encouraged for smokers with a strong family history of the disease
To detect invasive lung cancer in its early stages, researchers urge current and former smokers who have a strong family history of the disease to take a lung function test and undergo screening with spiral computed tomography.   view more (2006-01-03)

Oxford Biomedica Plc And Arius Research Inc. Sign Collaborative Programme In Tumour Immunotherapy
Oxford, United Kingdom and Toronto, Canada - 25 July 2002. Oxford BioMedica plc (LSE:OXB) ("BioMedica") and ARIUS Research Inc. ("ARIUS) of Canada announced today a research and development collaboration to search for targets and develop novel products to treat cancer. Under the... view more (2002-07-25)

Il-22 gene delivers the goods and decreases intestinal inflammation
There are two major types of inflammatory bowel disease (IBD), Crohn disease (CD) and ulcerative colitis (UC).   view more (2008-01-03)

Study identifies molecular process underlying leukemia
New research from the University of North Carolina at Chapel Hill has identified a molecular process in cells that is crucial to the development of two common leukemias.   view more (2006-08-22)

Gene therapy eradicates pancreatic cancer in preclinical trial
A molecularly engineered therapy selectively embeds a gene in pancreatic cancer that shrinks or eradicates tumors, inhibits metastasis, and prolongs survival with virtually no toxicity.   view more (2007-07-10)

Breast cancer gene mutation more common in Hispanic, young black women, Stanford/NCCC study finds
A genetic mutation already known to be more common in Ashkenazi Jewish breast cancer patients is also prevalent in Hispanic and young African-American women with breast cancer, according to one of the largest, multiracial studies of the mutation to date.   view more (2007-12-26)

Removal of ovaries decreases risk of certain cancers for women at high-risk
Women with mutations in the BRCA1 or BRCA2 genes can significantly reduce their risk of certain types of cancer by having their ovaries removed.   view more (2006-07-12)

Gene therapy protects mice from the effects of whole-body irradiation
University of Pittsburgh School of Medicine researchers have successfully protected mice against the damaging effects that radiation can have on bone marrow using gene therapy.   view more (2006-06-05)

Gold nanoparticles could improve antisense cancer drugs
In the fight against cancer, antisense drugs, which prevent genes from producing harmful proteins such as those that cause cancer, have the promise to be more effective than conventional drugs, but the pace of development of these new drugs has been slow.   view more (2006-05-19)

Imaging technology points to small molecules that can fight treatment-resistant tumors
Using a newly developed drug screen, researchers at the University of Pennsylvania School of Medicine have discovered small molecule compounds that are able to perform the functions of a gene commonly mutated in many types of cancer.   view more (2006-07-12)

Discovery of good -- and bad -- liver stem cells raises possibility of new treatment
Many scientists believe up to 40 percent of liver cancer is caused by stem cells gone wild - master cells in the organ that have lost all growth control. But, despite years spent looking, no one has ever found these liver "cancer stem cells" - or even normal stem cells in the organ. Until... view more (2008-02-11)

Women smokers have higher risk of lung cancer than men smokers, though lower lung cancer death rate
Women who smoke appear to be more susceptible to lung cancer than men who smoke, though women smokers have a lower rate of lung cancer-related death.   view more (2006-07-12)

Mouse gene shows new mechanism behind cardiac infarction in man
A gene that, in different variants, increases or decreases the level of atherosclerosis has been identified in mice. The corresponding human gene has been shown to play a role in the development of myocardial infarction. The results of the study is published this week on Nature Genetics Online.   view more (2005-03-08)

Scientists to assess effects of multiple copies of genes on disease risk
Scientists at Washington University School of Medicine in St. Louis and the biotech firm Nimblegen Systems Inc. have successfully tested a technique for identifying newly recognized DNA variations that may influence disease risk.   view more (2007-01-31)

H. Pylori bacteria may help prevent some esophageal cancers
Some bacteria may help protect against the development of a type of esophageal cancer, known as adenocarcinoma, according to a new review of the medical literature. These bacteria, which are called Helicobacter pylori, live in the stomachs of humans.    view more (2008-10-06)

Protein holds back growth of head and neck tumors
A protein associated with the growth of head and neck tumors may be a tumor suppressor that could prevent the spread of cancer when it is expressed above normal levels.   view more (2006-02-01)

Shoots but no droop in longer-lasting plants
Limp lettuce and wilting roses could be a thing of the past, following the identification of a key plant gene by University scientists. The discovery could also improve food shelf life, and help speed up reforestation programmes. Plant scientists Professor Meyer and Dr Elena Zubko have identified... view more (2002-04-25)

2 heads are better than 1: 2 dysfunctional DNA repair pathways kill tumor cells
Individuals who inherit two mutant copies of any one of about 12 genes that make the proteins of the Fanconi Anemia (FA) pathway develop FA, which is characterized by increased incidence of cancer and bone marrow failure, among other things.   view more (2007-04-13)

International team reveals first prognosticator of survival in aggressive cancer
The tumor suppressor gene pRb2/p130 may provide the first independent prognostic biomarker in cases of soft tissue sarcoma (STS).   view more (2008-09-04)

Small molecule derived from Rb2/p130 could act as cancer therapeutic
A small molecule derived from the spacer domain of the tumor-suppressor gene Rb2/p130 has demonstrated the ability to inhibit tumor growth in vivo and could be developed into an anti-cancer therapeutic, according to researchers at Temple University's Sbarro Institute for Cancer Research and... view more (2007-03-21)

Scientists discover anti-cancer mechanism that arrests early prostate cancer
Prostate cancer, the second leading cause of cancer death for men in the United States, is caused by changes in several tummor suppressor genes including PTEN and p53.   view more (2005-08-04)
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