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Study Shows Gene Variations May Predict Risk of Breast Cancer in Women
According to a recent study, led by Virginia Kaklamani, MD, an oncologist at Northwestern Memorial Hospital and assistant professor of medicine, Northwestern University Feinberg School of Medicine, variations of the adiponectin gene, which regulates a number of metabolic processes, may increase a... view more (2008-05-05)

Early predictor of breast cancer aggressiveness
Physicians may be able to make early decisions on the best treatment for breast cancer, thanks to research published in Breast Cancer Research today. A gene involved in the adhesion of cells is less active in breast tumors with a poor prognosis than those that are less aggressive, researchers... view more (2004-06-24)

Manchester researchers announce new methods of beating breast cancer
University of Manchester researchers will reveal new ways of controlling and treating breast cancer at the National Cancer Research Institute conference in Birmingham today (Monday 1 October 2007).   view more (2007-10-02)

Isolation of a new gene family essential for early development
Researchers at BRIC, University of Copenhagen, have identified a new gene family (UTX-JMJD3) essential for embryonic development. The family controls the expression of genes crucial for stem cell maintenance and differentiation, and the results may contribute sig-nificantly to the understanding of... view more (2007-08-23)

New advance in prostate cancer management
Scientists from The Institute of Cancer Research have developed a technique which will markedly help in predicting the behaviour of prostate cancer.   view more (2005-08-10)

Gene signature assesses breast cancer outcomes
A test that looks at the expression of 70 genes linked to breast cancer can accurately assess a patient's risk of recurrence or death.   view more (2006-09-06)

Analysis of breast-cancer gene role offers promising target
Researchers at UT Southwestern Medical Center have for the first time described how multiple copies of a gene are responsible for metastases in early-stage breast cancer and poor prognosis for patients.   view more (2006-10-31)

New therapy shows promise for fighting treatment-resistant cancer cells
A gene radiotherapy system that detects and treats cancer cells that are resistant to traditional forms of chemotherapy and radiation showed success in the laboratory and could eventually prove beneficial for cancer patients, according to researchers at SNM's 55th Annual Meeting.   view more (2008-06-17)

Mayo Clinic study finds two genes predict outcome for breast cancer patients
The 2-gene expression profile of HOXB13 and IL17BR in a woman's breast cancer predicts risk of recurrence in node-negative patients treated with tamoxifen.   view more (2006-04-03)

New gene test for prostate cancer at hand
Men with susceptibility for prostate cancer will soon be identifiable through a simple DNA test. So hope scientists at the Swedish medical university Karolinska Institutet, who have shown that men carrying a combination of known risk genes run a four to five times higher risk of developing prostate... view more (2008-01-18)

Another gene rearrangement involved in prostate cancer identified
Researchers at the University of Michigan Medical School have identified a third gene involved in prostate cancer, expanding their groundbreaking announcement, published last October in Science, that the majority of prostate cancers carry a malignancy-inducing fusion of genes never before seen in... view more (2006-04-04)

Novel mechanism of taxane resistance
Research Associate Chih-Jian Lih and others working in the laboratory of Dr. Stanley N. Cohen at Stanford University have pinpointed a gene that affects human cancer cells' sensitivity to chemotherapy-an important finding in the effort to increase the effectiveness of chemotherapy.   view more (2006-07-17)

Breast cancer amongst young women
Breast cancer is the most common and the second-most fatal malignant tumour amongst women who live in industrialised countries. Moreover, when present in young women, it would appear that a genetic predisposition is involved. This predisposition can be due to a number of causes and, amongst the... view more (2003-11-14)

Scientists identify a gene that may suppress colorectal cancer
In today's online edition of Genome Research, a husband-and-wife research team from Thomas Jefferson University report the discovery of a gene that, when mutated, may suppress colorectal cancer.   view more (2007-03-22)

metaGen and RNAx Announce Target Validation Agreement
metaGen Pharmaceuticals and RNAx announced today the signing of a target validation agreement. Under the terms of the agreement RNAx provides metaGen with access to RNA interference validation technology (RNAi). metaGen will employ this technology to validate proprietary gene targets relevant for... view more (2003-03-25)

SCIENTISTS TAKE A STEP CLOSER TO UNDERSTANDING BREAST CANCER GENEWorld first for Imperial Cancer Research Fund
Scientists from the Imperial Cancer Research Fund are the first in the world to solve the structure of an important region of a protein molecule made by the XRCC1 gene which has a role in human DNA repair. The same region is also found in the BRCA1 gene which is involved in breast cancer. Their... view more (1998-11-03)

Weight loss decreases risk of breast cancer in susceptible women
Women with a mutation in the gene BRCA1, which predisposes women to breast cancer, are 65% less likely to develop the disease if they lose weight between 18 and 30 years of age.   view more (2005-08-22)

Ovarian Cancer May Mimic Fallopian Tube Formation
A new study suggests that ovarian cancer cells form by hijacking a developmental genetic process normally used to form fallopian tubes. Scientists at the Georgia Institute of Technology and the Ovarian Cancer Institute discovered that the protein, PAX8, is involved in the development of fallopian... view more (2007-03-07)

Dual functions of gene revealed, for better and for worse
Researchers at WEHI have pinpointed the function of a potent cancer gene. The gene, known as "ERG", has long been associated with a range of human malignancies, including leukemia and sarcoma. American scientists showed in 2005 that ERG is mutated in more than half of all prostate... view more (2008-05-27)

New Cancer Gene Discovered
Researchers at the OU Cancer Institute have identified a new gene that causes cancer. The ground-breaking research appears Monday in Nature's cancer journal Oncogene.   view more (2008-05-09)

A search for biomarkers for early detection of colorectal cancer
Researchers at the Zhejiang University, Hangzhou have discovered that mimecan and Thioredoxin Domain-Containing Protein 5 (TXNDC5) were differentially expressed in colorectal adenoma.   view more (2007-09-25)

Firefly Light Helps Destroy Cancer Cells
Could the gentle firefly turn out to be a potent weapon against cancer? In a new study, researchers from London inserted the firefly gene that activates bioluminescent light into modified cancer cells, hoping to set off a chain of events that has a proven track record at fighting the disease. This... view more (2003-04-11)

Antibiotic inhibits cancer gene activity
A little-known antibiotic shows early promise as an anti-cancer agent, inhibiting a gene found at higher-than-normal levels in most human tumors.   view more (2006-10-02)

Jefferson scientists uncover gene mutation that cuts colon polyps, may suppress cancer
Cancer biologists at the Kimmel Cancer Center at Jefferson have found a gene mutation that can dramatically reduce the number of colon polyps that develop, and in turn, potentially cut the risk of cancer.   view more (2007-03-22)

Exposure to organic dissolvents may cause carcinogenic mutations
A study led by Universitat Autònoma de Barcelona researchers has shown that exposure to hydrocarbon-based organic dissolvents may provoke mutations in the k-ras oncogen, a gene which facilitates the appearance of tumours when it has mutated. The relationship has been demonstrated in... view more (2002-02-11)

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