Cancer Gene Current Events | Cancer Gene News | 4
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Ovarian Cancer May Mimic Fallopian Tube Formation
A new study suggests that ovarian cancer cells form by hijacking a developmental genetic process normally used to form fallopian tubes. Scientists at the Georgia Institute of Technology and the Ovarian Cancer Institute discovered that the protein, PAX8, is involved in the development of fallopian tubes and is present in ovarian cancer cells, but... view more... (2007-03-07)
Dual functions of gene revealed, for better and for worse
Researchers at WEHI have pinpointed the function of a potent cancer gene. The gene, known as "ERG", has long been associated with a range of human malignancies, including leukemia and sarcoma. American scientists showed in 2005 that ERG is mutated in more than half of all prostate cancers. view more (2008-05-27)
New Cancer Gene Discovered
Researchers at the OU Cancer Institute have identified a new gene that causes cancer. The ground-breaking research appears Monday in Nature's cancer journal Oncogene. view more (2008-05-09)
Moving gene therapy forward with mobile DNA
Gene therapy is the introduction of genetic material into a patient's cells resulting in a cure or a therapeutic effect. In recent years, it has been shown that gene therapy is a promising technology to treat or even cure several fatal diseases for which there is no attractive alternative therapy. view more (2009-05-04)
A search for biomarkers for early detection of colorectal cancer
Researchers at the Zhejiang University, Hangzhou have discovered that mimecan and Thioredoxin Domain-Containing Protein 5 (TXNDC5) were differentially expressed in colorectal adenoma. view more (2007-09-25)
Firefly Light Helps Destroy Cancer Cells
Could the gentle firefly turn out to be a potent weapon against cancer? In a new study, researchers from London inserted the firefly gene that activates bioluminescent light into modified cancer cells, hoping to set off a chain of events that has a proven track record at fighting the disease. This light source, known as Luciferin, caused the... view more... (2003-04-11)
Antibiotic inhibits cancer gene activity
A little-known antibiotic shows early promise as an anti-cancer agent, inhibiting a gene found at higher-than-normal levels in most human tumors. view more (2006-10-02)
Jefferson scientists uncover gene mutation that cuts colon polyps, may suppress cancer
Cancer biologists at the Kimmel Cancer Center at Jefferson have found a gene mutation that can dramatically reduce the number of colon polyps that develop, and in turn, potentially cut the risk of cancer. view more (2007-03-22)
Exposure to organic dissolvents may cause carcinogenic mutations
A study led by Universitat Autònoma de Barcelona researchers has shown that exposure to hydrocarbon-based organic dissolvents may provoke mutations in the k-ras oncogen, a gene which facilitates the appearance of tumours when it has mutated. The relationship has been demonstrated in pancreatic cancer patients who had been exposed to the... view more... (2002-02-11)
Protein protects anti-cancer gene from chemical shutdown
A protein that is largely absent in one type of skin cancer protects an important gene in a cell's defense against harmful mutations from being silenced. view more (2007-07-20)
Researchers identify new anti-tumor gene
Researchers from Virginia Commonwealth University have identified a new anti-tumor gene called SARI that can interact with and suppress a key protein that is overexpressed in 90 percent of human cancers. The discovery could one day lead to an effective gene therapy for cancer. view more (2008-12-17)
Jefferson Scientists See Breast Cancer Gene Activity from Outside the Body
Researchers at Jefferson Medical College and Jefferson's Kimmel Cancer in Philadelphia have used PET imaging to see hyperactive cancer genes inside breast tumors in laboratory animals, marking the first time such gene activity has been observed from outside the body. view more (2007-11-29)
Cancer-resistant mouse discovered
A mouse resistant to cancer, even highly-aggressive types, has been created by researchers at the University of Kentucky. view more (2007-11-27)
No single gene for ageing
According to professor Thomas Kirkwood of the University of Newcastle, there is no single gene for ageing. view more (2005-09-13)
New target for cancer therapy identified
A new target for cancer therapy has been identified by Monash University scientists investigating the cell signalling pathways that turn on a gene involved in cancer development. view more (2006-09-22)
Glypican-3 gene function in regulating body size helps inform novel cancer treatments
In a leading study that has implications for the development of novel therapies for a number of breast, lung and ovarian cancers that have lost the expression of a gene called glypican-3 (GPC3), Sunnybrook researchers have discovered how the loss of the GPC3 gene induces overgrowth through certain growth factors such as Sonic Hedgehog which... view more... (2008-05-13)
New study shows way to avoid overtreatment in breast cancer
The numbers of women who receive adjuvant chemotherapy for breast cancer could be reduced by 30 to 40% if the results of a new molecular study are put into practice. Dr Laura van 't Veer from the Netherlands Cancer Institute told the news briefing that micro array technology* can help predict which breast cancers will metastasise (spread) and... view more... (2002-03-20)
A breakthrough in gastric carcinogenesis
Checkpoint with forkhead and ring finger (CHFR) is a mitotic stress checkpoint gene whose promoter is frequently methylated in various kinds of cancer. view more (2009-06-12)
EMSY: a new gene for breast/ovarian cancer
A new human breast and ovarian cancer gene has just been described by investigators in the last issue of the journal Cell. The gene, called EMSY, also characterises a subset of breast cancer with poorer survival, which makes it a potentially important diagnostic tool. view more (2003-12-10)
Gene may hold key to future cancer hope
Scientists may have discovered a new way of killing tumours in what they hope could one day lead to alternative forms of cancer treatments. view more (2007-10-09)
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