Cancer Gene Current Events | Cancer Gene News | 7
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Gene therapy may protect normal tissues during radiation retreatment for lung cancer
Gene therapy could be used as an agent to protect normal tissues, including the esophagus and lung, from damage during a second administration of radiation therapy for non-small cell lung cancer. view more (2005-10-17)
Newly discovered gene may predict aggressive ovarian cancer
Johns Hopkins Kimmel Cancer Center researchers have linked alterations in a gene, called Rsf-1, to the most deadly ovarian cancers. view more (2005-09-30)
Defects in critical gene lead to accelerated lung tumor growth
Cancer causing mutations occur in our bodies every day - but luckily, we have specific genes that recognize these malignant events and keep cells from growing out of control. Only a few of these genes - called tumor suppressors - are currently known. view more (2007-08-06)
Sun exposure early in life linked to specific skin cancer gene mutation
Skin cancers often contain different gene mutations, but just how these mutations contribute to the cause of melanomas has been a mystery. view more (2007-06-11)
A new soldier in the war on cancer: The blind mole rat
If someone ever calls you a "dirty rat," consider it a compliment. A new discovery published online in the FASEB Journal shows that cellular mechanisms used by the blind mole rat to survive the very low oxygen environment of its subterranean niche are the same as those that tumors use to thrive deep in our tissues. view more (2009-03-05)
Henry Ford Hospital expands research on gene and radiation therapy for prostate cancer
Henry Ford Hospital is embarking on an expanded major clinical trial involving the use of gene therapy in combination with radiation therapy, to determine if the combined treatment is more effective than radiation therapy alone for patients with intermediate risk prostate cancer. view more (2008-02-07)
OHSU Cancer Institute researchers find connection between protein, prognosis in breast cancer
Oregon Health & Science University Cancer Institute researchers have found that a tumor protein present in an aggressive form of breast cancer is related to a poor prognosis. view more (2008-04-14)
Study reveals why certain ovarian cancers develop resistance to platinum-based chemotherapy
A team of researchers led by Fred Hutchinson Cancer Research Center has identified a new mechanism that explains why some recurrent ovarian tumors become resistant to treatment with commonly used platinum-based chemotherapy drugs such as cisplatin and carboplatin. They describe their research online Feb. 10 in the journal Nature. view more (2008-02-11)
Colorectal cancer : A new way of increasing the efficacy of chemotherapy
Inserm and CNRS research scientists and doctors at the Institut Curie have demonstrated the influence of the status - mutated or functional - of the tumour suppressor gene p53 in the response of colorectal cancer to chemotherapy. Tumours in which the p53 gene is mutated respond less well to treatment. However, by adding another agent, researchers... view more... (2004-02-27)
Environmental exposures may damage DNA in as few as 3 days
Exposure to particulate matter has been recognized as a contributing factor to lung cancer development for some time, but a new study indicates inhalation of certain particulates can actually cause some genes to become reprogrammed, affecting both the development and the outcome of cancers and other diseases. view more (2009-05-18)
Researchers find new gene linked to breast cancer
Researchers in a multicenter international study have identified a new gene that, if mutated, may increase a woman's risk of breast cancer by more than a third. view more (2007-10-08)
Getting down to cancer basics
Researchers have identified a new cancer gene - one that is common to many cancers and affects the most basic regulation of our genes. The new example - a gene on the X chromosome called UTX - is found in 10% of cases of multiple myeloma and 8% of esophageal cancers. view more (2009-03-30)
Gene Signature Can Predict Breast Cancer Spread
Researchers have discovered a genetic signature that can identify breast cancer patients at high risk of distant recurrence, reporting their results in this week's issue of The Lancet. view more (2005-02-16)
MGH Cancer Center researchers find new gene associated with Wilms tumor
Researchers at the Massachusetts General Hospital (MGH) Cancer Center have discovered a novel gene mutation associated with Wilms tumor, the most common pediatric kidney cancer. view more (2007-01-05)
Targeting Tumor Behavior May Lead To New Liver Cancer Drugs
Ohio State University cancer researchers have used computational and genomic methods to identify possible anti-cancer agents that may block a particular kind of tumor behavior. view more (2009-06-19)
Extra copies of EGFR gene signal poor prognosis for vulvar cancer
A genetic fingerprint identified in patients with a gynecologic cancer may reveal candidates for targeted therapy. view more (2008-10-01)
U-M researchers discover gene switched off in cancer can be turned on
A gene implicated in the development of cancer cells can be switched on using drugs, report researchers from the University of Michigan Comprehensive Cancer Center. view more (2007-06-12)
Gene fusion discovery may lead to improved prostate cancer test
A newly discovered gene fusion is highly expressed in a subset of prostate cancers, according to a study by researchers at Weill Cornell Medical College. view more (2009-04-10)
Gene for neat repair of DNA discovered
Researchers from the Erasmus University in Rotterdam have demonstrated that a gene helps in the neat repair of DNA. Without this gene the body would repair damaged DNA in a careless manner more often. This causes new damage, which can lead to cancer. The careless repair of damaged DNA can cause mutations and can result in cancer. Cell biologists... view more... (2002-01-24)
Abnormal DNA repair genes may predict pancreatic cancer risk
Abnormalities in genes that repair mistakes in DNA replication may help identify people who are at high risk of developing pancreatic cancer, a research team from The University of Texas M. D. Anderson Cancer Center reports in the Jan. 15 issue of Clinical Cancer Research. view more (2009-01-16)
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