Cancer Gene Current Events | Cancer Gene News | 8
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Molecular 'clock' could predict risk for developing breast cancer
A chemical reaction in genes that control breast cancer provides a molecular clock that could one day help researchers more accurately determine a woman's risk for developing breast cancer and provide a new approach for treatment, UT Southwestern Medical Center researchers have found. view more (2008-05-14)
Genes raise risk of heart disease after treatment for childhood cancer
Gene variations may raise the risk that survivors of childhood cancer will suffer congestive heart failure as a complication of drugs they received during cancer treatment. view more (2006-06-05)
Multicenter study nets new lung tumor-suppressor gene
Collaborating scientists in Boston and North Carolina have found that a particular gene can block key steps of the lung cancer process in mice. view more (2007-08-06)
Cancer immunoresistance linked to loss of tumor suppressor gene
Cancer immunoresistance may be partially due to loss of a well-known tumor suppressor gene, according to new research led by Andrew T. Parsa, MD, PhD, assistant professor of neurological surgery at the University of California, San Francisco. view more (2006-12-11)
Encouraging results from validation study give green light for a trial of personalised treatment in breast cancer
The overall performance of the gene signature to be used in the first large-scale trial to study the role of such tumor signatures in breast cancer is encouraging and gives the green light to start the trial proper, Dr. Martine Piccart, head of the medical oncology department at the Institut Jules Bordet in Brussels, Belgium, told the San Antonio... view more... (2004-12-06)
Cell-regulating gene may predict survival outcomes for breast cancer patients
A study led by researchers at Mount Sinai School of Medicine has shown that a cell-regulating gene overexpressed in about 30 to 50 percent of all breast cancers is associated with a better chance of survival and increased sensitivity to a cancer-fighting drug. view more (2006-09-06)
Dormant cancer cells rely on cellular self-cannibalization to survive
A single tumor-suppressing gene is a key to understanding, and perhaps killing, dormant ovarian cancer cells that persist after initial treatment only to reawaken years later, researchers at The University of Texas M. D. Anderson Cancer Center report in the December Journal of Clinical Investigation. view more (2009-01-05)
Genetic marker may predict early onset of prostate cancer
Fox Chase Cancer Center researchers have identified a genetic marker that is associated with an earlier onset of prostate cancer in Caucasian men who have a family history of prostate cancer. view more (2009-05-18)
Human cells secrete cancer-killing protein, UK study finds
Human cells are able to secrete a cancer-killing protein, scientists at the University of Kentucky's Markey Cancer Center have found. view more (2009-07-24)
Change in gene may be underlying molecular defect in some colorectal cancers, study suggests
Inactivation of a DNA repair gene may be an early step in the development of sporadic colorectal tumors, and detection of the molecular basis for this inactivation may ultimately be useful in risk assessment for colorectal cancer. view more (2005-09-21)
Genetic Link Uncovered in Disparate Colon Cancer Death
A new study reveals the first-ever genetic link to the reason African-Americans are at increased risk of dying from colon cancer. view more (2009-04-01)
Abnormal overexpression of p53 is a predictive molecular biomarker
A common laboratory test that predicted poor outcome from traditional radiation and chemotherapy treatment for head and neck cancers now has been found to predict a good prognosis with treatment of p53 tumor suppressor gene therapy-making it potentially the first predictive biomarker test for a gene-based drug. view more (2006-09-15)
CSHL researchers discover three new genes that cause lung cancer
Researchers at Cold Spring Harbor Laboratory (CSHL) have discovered three genes that interact with cancerous results in 20% of lung cancers. view more (2007-10-09)
Researchers may have unlocked the mechanisms that silence the estrogen receptor gene alpha during breast cancer
The mechanisms that silence the estrogen receptor gene alpha (ER-α) in certain breast cancer cell lines may be closer to being unlocked. view more (2007-08-20)
Cancer signatures uncovered
A new systematic analysis of the relationship between the neoplastic and developmental transcriptome provides an outline of trends in cancer gene expression. view more (2008-08-18)
Dual gene therapy suppresses lung cancer in preclinical test
Combination gene therapy delivered in lipid-based nanoparticles drastically reduces the number and size of human non-small cell lung cancer tumors in mice. view more (2007-01-15)
Study identifies common flaws in oncology microarray studies
A substantial percentage of microarray-based studies in oncology contain critical flaws in analysis or in their conclusions, reports a study in the January 17 issue of the Journal of the National Cancer Institute. view more (2007-01-17)
Breast cancer: Risk increases for smokers and overweight women
A recent study published in the Journal of Cancer Epidemiology has reinforced the correlation between being overweight, smoking and breast cancer. view more (2009-09-02)
Genetic mutation associated with increased risk of lung cancer
Carriers of a common genetic disorder previously linked to lung disease may have a 70-percent to 100-percent increased risk of lung cancer, according to a report in the May 26 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. view more (2008-05-27)
Common viruses may cause cancer
In some cases, the fusion of human cells is a normal process that leads, for instance, to the formation of muscle and bone. Viral infections can also cause cell fusion, but cells fused by viruses are widely considered to be harmless because they are generally believed to die without consequences for the host. view more (2005-11-09)
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