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Cancer Gene News | Cancer Gene Current Events
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Skin flaps deliver cancer-fighting therapy, ASPS study reveals
Using gene therapy, plastic surgeons have delivered cancer fighting proteins through skin flaps placed on cancerous tumors on rats with a 79 percent reduction in tumor volume.   view more (2008-05-09)

Genes that both extend life and protect against cancer identified
A person is 100 times more likely to get cancer at age 65 than at age 35. But new research reported today in the journal "Nature Genetics" identifies naturally occurring processes that allow many genes to both slow aging and protect against cancer in the much-studied C. elegans roundworm.   view more (2007-10-15)

Jefferson scientists identify protein key to breast cancer spread, potential new drug target
Researchers at the Kimmel Cancer Center at Jefferson have identified a protein that they say is key to helping a quarter of all breast cancers spread.   view more (2007-04-10)

Gene chip data improved therapy in some patients with incurable cancer
Like many oncologists, Eric P. Lester, M.D., was faced with a dilemma: seven patients with advanced, incurable cancer, an arsenal of drugs that may or may not help them, and not enough solid proof about treatment efficacy to guide him.   view more (2007-09-20)

Lung cancer cells' survival gene seen as drug target
One of the deadliest forms of cancer appears to carry a specific weakness.   view more (2008-01-02)

Skin cancer breakthrough - Gene explains why men are at higher risk of malignant melanoma
Researchers from Germany have identified a gene that is associated with an increased risk of suffering from skin cancer. The research, published this month in Journal of Carcinogenesis, could also explain why men are more likely to suffer from malignant melanoma than women. Although most people... view more (2003-11-26)

A new way to treat colon cancer?
Researchers at University of Utah's Huntsman Cancer Institute have discovered a new target for possible future colon cancer treatments - a molecule that is implicated in 85 percent of colon cancer cases.   view more (2006-10-10)

Lung cancer cells' survival gene seen as drug target
When a key gene called 14-3-3zeta is silenced, lung cancer cells can't survive on their own, researchers have found.   view more (2007-12-26)

Novel enzyme offers new look at male hormone regulation
For the second time in less than a year, University of North Carolina at Chapel Hill scientists have purified a novel protein and have shown it can alter gene activity by reversing a molecular modification previously thought permanent.   view more (2006-05-08)

Mouse study reveals human X-SCID gene therapy poses substantial cancer risk
New animal studies conducted at the Salk Institute for Biological Studies show that the only human gene therapy treatment to date considered to be largely successful, is, in fact, riskier than realized.   view more (2006-04-27)

University of Washington-led team discovers a gene that causes familial pancreatic cancer
An international group of researchers has discovered that the mutated form of a gene called Palladin causes familial pancreatic cancer.   view more (2006-12-13)

Vitamin D protects cells from stress that can lead to cancer
By inducing a specific gene to increase expression of a key enzyme, vitamin D protects healthy prostate cells from the damage and injuries that can lead to cancer, University of Rochester Medical Center researchers report.   view more (2008-05-14)

'Smothered' genes combine with mutations to yield poor outcome in cancer patients
Johns Hopkins Kimmel Cancer Center researchers have identified a set of genes in breast and colon cancers with a deadly combination of traditional mutations and "smothered" gene activity that may result in poor outcomes for patients.   view more (2008-07-16)

New pathway provides more clues about BRCA1 role in breast cancer
A breast cancer gene's newly discovered role in repairing damaged DNA may help explain why women who inherit a mutated copy of the gene are at increased risk for developing both breast and ovarian cancer.   view more (2008-01-16)

Cancer cells 'reprogram' energy needs to grow and spread, study suggests
Studying a rare inherited syndrome, researchers at Johns Hopkins have found that cancer cells can reprogram themselves to turn down their own energy-making machinery and use less oxygen, and that these changes might help cancer cells survive and spread.   view more (2007-05-08)

Gene expression test reveals ER and HER-2 status of breast tumors
Two critical characteristics of breast cancer that are important to treatment can be identified by measuring gene expression in the tumor, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in Lancet Oncology online.   view more (2007-02-15)

Scientists Develop Technology To Detect Cancer
Researchers at the University of Liverpool have developed a breakthrough technology that identifies molecular markers in early lung cancer.   view more (2005-04-20)

Ireland Cancer Center researchers advance stem cell gene therapy
Ireland Cancer Center of University Hospitals Case Medical Center researchers have recently made great strides in stem cell gene therapy research by transferring a new gene to cancer patients, via their own stem cells, with the ultimate goal of being able to use stronger chemotherapy treatment with... view more (2007-12-13)

UC Davis researchers discover genetic switch involved in cells' response to radiation therapy
UC Davis Cancer Center researchers have discovered a genetic switch that causes cancer cells to become more sensitive to a drug administered to enhance radiation therapy effectiveness.   view more (2005-11-17)

Newfound roadblock to interferon effectiveness against malignant melanoma
Researchers have uncovered a significant contributing factor to interferon resistance of malignant melanoma cells.   view more (2005-09-22)

Scientists discover that metastases share a similar genetic profile to their primary tumour
Hamburg, Germany: Work by scientists in The Netherlands has contradicted the notion that breast cancer metastases behave differently to their primary tumours. PhD student, Britta Weigelt told the meeting of the 4th European Breast Cancer Conference today (Thursday 18 March) that, contrary to what... view more (2004-03-16)

DNA scans reveal possible location of lung cancer genes
With equipment designed to probe the smallest segments of the genetic code, researchers at Dana-Farber Cancer Institute and collaborating institutions have found something much larger: sections of the chromosomes of lung cancer cells where cancer-related genes may lurk.   view more (2005-07-01)

Biomarker predicts malignancy potential of HG-PIN lesions in the prostate
Men whose prostate cancer screenings show high grade prostatic intraepithelial neoplasia (HG-PIN) may find themselves in limbo, "stuck" between diagnoses - they are told prostate cancer has not yet developed, but it might, and they are advised to undergo repeated needle biopsies as a... view more (2008-05-01)

Human Cytomegalovirus May Be Involved In Colorectal Cancer (p 1557)
Preliminary findings of a study in this week's issue of THE LANCET suggest that a common human virus may play a part in the cellular processes involved in the development of colorectal cancer. Colorectal cancer is the second most frequent cause of death from cancer in many developed countries;... view more (2002-11-13)

New study shows that therapeutic gene expression can be sustainable for 1 year
Researchers at the Board of Governors Gene Therapeutics Research Institute at Cedars-Sinai Medical Center have shown for the first time that it is possible to sustain therapeutic gene expression in the central nervous system for up to a year, even in the presence of an anti-viral immune response... view more (2007-10-26)
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