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Stoned sea-squirts
The psychoactive ingredient of the drug cannabis exerts its effects on the human brain by activating proteins known as cannabinoid receptors. Dr. Maurice Elphick of Queen Mary, University of London has uncovered the first evidence that cannabinoid receptors may not be unique to humans and other... view more (2004-03-31)

Marijuana-like compounds suppress the immune response
A group of Japanese scientists has discovered that cannabinoids can cause some white blood cells to lose their ability to migrate to the sites of infection and inflammation.   view more (2006-04-27)

U of Minnesota researcher discovers the starting point of sun-induced skin cancer
According to a new study from the University of Minnesota, the earliest event in the development of sun-induced skin cancer may have been identified.   view more (2008-05-15)

Study shows enzyme builds neurotransmitters via newly discovered pathway
The new study describes a pathway-different than the one previously suggested-for the biosynthesis of neurotransmitter lipids, N-acyl ethanolamines (NAEs), which include the endogenous cannabinoid ("endocannabinoid") anandamide.   view more (2006-09-12)

Opioids and cannabinoids influence mobility of spermatozoids
A PhD thesis from the University of the Basque Country has concluded that there are opioid and cannabinoid receptors in human sperm and that these influence the mobility of spermatozoid.   view more (2008-06-23)

New Mount Sinai research tracks effects of addictive drugs on brain
Mount Sinai researchers may have unlocked the key to better understanding the effect addictive drugs have on the human brain.   view more (2008-05-16)

Good news for the medical marijuana movement: pot proliferates brain cells and boosts mood
Most drugs of abuse decrease the generation of new neurons in the brain, but the effects of marijuana on this process, called neurogenesis, had not been clear.   view more (2005-10-14)

New brain cells implicated in machinery of cannabinoid signaling
The brain cells called astrocytes, and not just neurons, are sensitive to the substances called cannabinoids-the active chemicals in marijuana.   view more (2008-03-27)

Marijuana component opens the door for virus that causes Kaposi's sarcoma
The major active component of marijuana could enhance the ability of the virus that causes Kaposi's sarcoma to infect cells and multiply.   view more (2007-08-02)

Synthetic Cannabinoid May Aid Fertility in Smokers
A reproductive medicine specialist at the University at Buffalo has shown that a new compound may improve the fertility of tobacco smokers who have low sperm count and low percentage sperm motility.   view more (2006-12-04)

Role seen for cannabis in helping to alleviate allergic skin disease
Administering a substance found in the cannabis plant can help the body's natural protective system alleviate an allergic skin disease (allergic contact dermatitis), an international group of researchers from Germany, Israel, Italy, Switzerland and the U.S. has found.   view more (2007-08-17)

Schizophrenia linked to dysfunction in molecular brain pathway activated by marijuana
Alterations in a molecular brain pathway activated by marijuana may contribute to the cognitive symptoms of schizophrenia, according to a report in the July issue of Archives of General Psychiatry, one of the JAMA/Archives journals.   view more (2008-07-08)

Antibodies can halve risk of transplant rejection
Giving interleukin-2 receptor antibodies to patients after a kidney transplant can halve the risk of rejection, concludes a study in this week's BMJ. Researchers in Birmingham reviewed eight trials of interleukin-2 receptor antibodies versus placebo in 1,858 patients receiving standard... view more (2003-04-10)

MIT study suggests caution on new anti-obesity drug in kids
Anti-obesity drugs that work by blocking brain molecules similar to those in marijuana could also interfere with neural development in young children, according to a new study from MIT's Picower Institute for Learning and Memory.   view more (2008-05-08)

Inhaled asthma drugs more effective than oral therapy
Inhaled glucocorticoid drugs are more effective than the newer anti-leukotriene tablets for adults with mild or moderate asthma, concludes a study in this week’s BMJ.   view more (2003-03-19)

A Novel Strategy for Combating Aids-Related Fungal Infections
Research at the Sir William Dunn School of Pathology has identified Dectin-1 as the beta-glucan receptor on immune cells. This finding may be of use in the prophylactic prevention of a variety of infections, especially in surgical patients, and in the treatment of cancer. The identification of... view more (2004-10-08)

New target for obesity and related metabolic disorders
A new study reveals an attractive new target for therapies aimed at the treatment of obesity and related metabolic disorders, researchers report in the March Cell Metabolism.   view more (2006-03-08)

Researchers identify taste receptor responsible for caffeine detection
By studying how taste-receptor mutations impact fruit fly behavior, researchers have identified a taste receptor responsible for the detection of caffeine, a bitter compound known to activate certain taste-receptor neurons, as well as impact various aspects of physiology.   view more (2006-09-19)

The secret of internal bliss revealed
Scientists now know for sure how cannabis works in the brain. By studying naturally occuring cannabinoids they have found that cannabis 'speaks' to nerve cells instructing them to stop releasing their chemical neurotransmitters so dumbing down their effects. The upside is that it makes cannabis... view more (2001-04-03)

Marijuana compound may help stop diabetic retinopathy
A compound found in marijuana won't make you high but it may help keep your eyes healthy if you're a diabetic, researchers say.   view more (2006-02-28)

Hebrew University scientists develop prototype drug to prevent osteoporosis
Substances produced in the body that act like those found in the cannabis plant help preserve bone density, according to researchers at the Hebrew University of Jerusalem. Based on this finding, a prototype for a new drug to prevent osteoporosis (loss of bone density) without any psychoactive side... view more (2006-01-04)

A novel model to pinpoint human androgen receptor targets developed
A novel computational model to pinpoint androgen receptor targets within the human genome was recently reported.   view more (2005-11-01)

Breathe deep: Which patients could benefit from inhaled steroids in cystic fibrosis?
A specific variation in the glucocorticoid receptor gene is associated with lung disease progression in cystic fibrosis, research published this week in the online open access journal Respiratory Research reveals.   view more (2007-11-29)

Study: cannabis a double-edged sword
A new neurobiological study has found that a synthetic form of THC, the active ingredient in cannabis, is an effective anti-depressant at low doses. However, at higher doses, the effect reverses itself and can actually worsen depression and other psychiatric conditions like psychosis.   view more (2007-10-24)

The endocannabinoids: Functional roles and therapeutic opportunities
Cannabis (marijuana) is the most widely produced plant-based illicit drug worldwide and the illegal drug most frequently used in Europe. Its use increased in almost all EU countries during the 1990s, in particular among young people, including school students.   view more (2007-10-15)

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