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Bioengineered tissue implants regenerate damaged knee cartilage
Knee cartilage injuries can be effectively repaired by tissue engineering and osteoarthritis does not stop the regeneration process concludes research led by scientists at the University of Bristol.   view more (2006-07-05)

Signaling for cartilage
Skeletal progenitor cells differentiate into cartilage cells when one master gene actually suppresses the action of another, said Baylor College of Medicine researchers in a report that appears online in the journal Proceedings of the National Academy of Sciences.   view more (2006-11-28)

HRT prevents osteoarthritis of the knee
Long term use of hormone replacement therapy (HRT) seems to protect women from osteoarthritis of the knee, finds a study in the Annals of the Rheumatic Diseases. Osteoarthritis is the most common type of arthritis. It most often occurs in hip and knee joints, where loss of the tissue which prevents joint friction - cartilage - exposes the bone... view more... (2001-03-12)

Vigorous physical activity in children likely to stave off knee osteoarthritis in later life
Young children need to be highly physically active if they are to stave off degenerative joint disease, specifically osteoarthritis of the knee, suggest researchers in the British Journal of Sports Medicine.   view more (2003-09-25)

MIT: New tissue scaffold regrows cartilage and bone
MIT engineers and colleagues have built a new tissue scaffold that can stimulate bone and cartilage growth when transplanted into the knees and other joints.   view more (2009-05-12)

Glucosamine supplements reduce knee pain
Glucosamine supplements reduce knee pain in people with cartilage damage and possibly the degenerative joint disease osteoarthritis, concludes research in the British Journal of Sports Medicine.   view more (2003-01-24)

The knee op that helps free the knees up
Most people over the age of 30 have some sort of problem with their knees making walking, running or playing sport uncomfortable, and thousands of people each year have surgery to remove damaged cartilage from within their knees.   view more (2000-01-20)

Smokers risk more painful and progressive osteoarthritis
Smokers risk more painful and progressive osteoarthritis than non-smokers, suggests research published ahead of print in the Annals of the Rheumatic Diseases.   view more (2006-12-07)

Woven scaffolds could improve cartilage repair
Using a unique weaving machine of their design, Duke University Medical Center researchers have created a three-dimensional fabric "scaffold" that could greatly improve the ability of physicians to repair damaged joints with the patient's own stem cells.   view more (2007-02-07)

Scientists use stem cells to grow cartilage
Scientists from Imperial College London have successfully converted human embryonic stem cells into cartilage cells, offering encouragement that replacement cartilage could one day be grown for transplantation.   view more (2005-11-17)

MDCT Arthrography Good for Assessing Hip Dysplasia
MDCT arthrography is an accurate method for assessing cartilage loss in patients with hip dysplasia and may be more reliable than MRI in such instances.   view more (2005-08-08)

Scripps research scientists find cause of cartilage degeneration in osteoarthritis
The scientists describe their work in this week's Early Edition of the Proceedings of the National Academy of Sciences. In the study, the team shows how the loss of the protein HMGB2, found in the surface layer of joint cartilage, leads to the progressive deterioration of the cartilage that is the hallmark of osteoarthritis.   view more (2009-01-13)

Obesity contributes to rapid cartilage loss
Obesity, among other factors, is strongly associated with an increased risk of rapid cartilage loss, according to a study published in the August issue of Radiology.    view more (2009-07-14)

Cartilage discovery offers arthritis hope
Scientists have revealed the intricate structure of cartilage in what they hope will provide clues to how the crippling joint disease osteoarthritis might one day be treated.   view more (2007-01-11)

New Imaging Methods for Joints Provide Boost for Combating Osteoarthritis
Osteoarthritis is the most common joint disorder in the UK and affects more than one million people. In this disease the cartilage, the tough, slippery tissue that coats the end of the bones and provides smooth movement and shock absorbence, roughens and thins, and the surrounding bone grows thicker. Approximately 60% of people have osteoarthritis... view more... (1999-09-08)

Researchers pinpoint enzyme involved in arthritis onset
Researchers from Cardiff University have uncovered a molecular pathway that plays a pivotal role in the onset of arthritis. Their research, published this week in Arthritis Research & Therapy, could aid in the discovery of novel targets for arthritis drugs. The researchers found that inhibiting the enzyme PKR could prevent two processes... view more... (2003-11-06)

Brown researchers work toward ending cartilage loss
Scientists have long wrestled with how to aid those who suffer cartilage damage and loss. One popular way is to inject an artificial gel that can imitate cartilage's natural ability to act as the body's shock absorber. But that solution is temporary, requiring follow-up injections.   view more (2008-06-04)

How movement lubricates bone joints
Taking a cue from machines that gently flex patients' knees to help them recover faster from joint surgery, bioengineering researchers at UC San Diego have shown that sliding forces applied to cartilage surfaces prompt cells in that tissue to produce molecules that lubricate and protect joints.   view more (2006-12-05)

Study identifies potential fix for damaged knees
Investigators from Hospital for Special Surgery have shown that a biodegradable scaffold or plug can be used to treat patients with damaged knee cartilage.   view more (2009-07-09)

Smoking worsens knee osteoarthritis
New findings from a study led by a Mayo Clinic rheumatologist indicate that men with knee osteoarthritis who smoke experience greater cartilage loss and more severe pain than men who do not smoke. Results will be published online this week in the Annals of the Rheumatic Diseases.   view more (2006-12-07)
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