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Outsmarting cancer - new results from novel enzyme inhibitors
Smart drugs that can break the chain of command between enzymes and the genes involved in cell division and cell death are a new way forward in tackling breast cancer, according to Dr Stephen Johnston, a consultant oncologist from The Royal Marsden Hospital, London, UK. He was speaking at a news briefing on Thursday (21 March) at the 3rd European... view more... (2002-03-19)
Potential New Therapeutic Molecular Target to Fight Cancer
Researchers at the Virginia Commonwealth University Massey Cancer Center have identified the enzyme sphingosine kinase 2 as a possible new therapeutic target to improve the efficacy of chemotherapy for colon and breast cancer. view more (2007-11-02)
Biologists use computers to study bacterial cell division
A group of computational biologists at Virginia Tech have created a mathematical model of the process that regulates cell division in a common bacterium, confirming hypotheses, providing new insights, identifying gaps in what is understood so far, and demonstrating the role of computation in biology. view more (2008-01-25)
Rivers are carbon processors, not inert pipelines
Microorganisms in rivers and streams play a crucial role in the global carbon cycle that has not previously been considered. view more (2008-12-02)
A new light on the anti-tumor mechanisms of Scutellaria barbata
Medicinal plants have been used as traditional remedies for hundreds of years. Among them, S. barbata has been traditionally used in treatment of hepatitis, inflammation, osteomyelitis and gynecological diseases in China. view more (2009-01-05)
How DDT metabolite disrupts breast cancer cells
Research has shown that the main metabolite of the insecticide DDT could be associated with aggressive breast cancer tumours, but there has been no explanation for this observation to date. Now a report published in the open access journal Breast Cancer Research shows how DDT could act to disrupt hormone-sensitive breast cancer cells. view more (2008-02-14)
Decoded gene sequence of the diatom Thalassiosira pseudonana
For the very first time, the genetic make-up of a planktonic marine alga has been sequenced. During this process, a team of international scientists found unexpected metabolic pathways in the diatom Thalassiosira pseudonana. The results will be published in the scientific journal 'Science' this week. view more (2004-10-01)
An AIDS-related virus reveals more ways to cause cancer, Penn researchers find
Researchers at the University of Pennsylvania School of Medicine have shed new light on how Kaposi's Sarcoma-associated Herpes Virus (KSHV) subverts normal cell machinery to cause cancer. view more (2007-10-09)
Gladstone investigators identify a new protective action for the powerful anti-HIV factor, APOBEC3G
Scientists at the Gladstone Institute of Virology and Immunology (GIVI) have identified a previously unknown function of APOBEC3G (A3G), a protein that acts against HIV, a finding that may lead to new approaches for controlling HIV infection. view more (2006-10-03)
Unmasking the "Foreman" Of The Golgi Apparatus
The cell is a highly organized factory where each constituent has its place and a role to play. If one piece of this machinery falters, the whole cell is imperiled. The least anomaly may result in an uncontrolled cell likely to engender a variety of diseases, such as cancers. At the Institut Curie, CNRS researchers, in collaboration with a group... view more... (2004-08-05)
Hair-raising stem cells identified
Using an animal model, a research team led by Yann Barrandon at the EPFL (Ecole Polytechnique Federale de Lausanne) and the CHUV (Lausanne University Hospital) has discovered that certain cells inside the hair follicle are true multipotent stem cells, capable of developing into the many different cell types needed for hair growth and follicle... view more... (2005-10-05)
Clock molecule's sensitivity to lithium sheds light on bipolar disorder
Researchers at the University of Pennsylvania School of Medicine discovered that a key receptor protein is a critical component of the internal molecular clock in mammals. What's more, this molecule -called Rev-erb- is sensitive to lithium and may help shed light on circadian rhythm disorders, including bipolar disorder. view more (2006-02-17)
A potential therapeutic target for gastric cancer
Gastric cancer (GC) is the fourth most common malignancy and the second most frequent cause of cancer-related death in the world. view more (2009-04-17)
Odd energy mechanism in bacteria analyzed
Scientists at Oregon State University have successfully cultured in a laboratory a microorganism with a gene for an alternate form of photochemistry - an advance that may ultimately help shed light on the ecology of the world's oceans. view more (2005-11-04)
Biological Timekeeper Studies Reveal New Temperature Regulator and Track Clock Protein across a Day
Dartmouth Medical School geneticists have made new inroads into understanding the regulatory circuitry of the biological clock that synchronizes the ebb and flow of daily activities. view more (2009-05-18)
Earth's biogeochemical cycles, once in concert, falling out of sync
What do the Gulf of Mexico's "dead zone," global climate change, and acid rain have in common? They're all a result of human impacts to Earth's biology, chemistry and geology, and the natural cycles that involve all three. view more (2009-08-04)
Study finds hereditary link to premenstrual depression
A specific genetic variation may be tied to an increased risk for severe premenstrual depression, scientists at the University of North Carolina at Chapel Hill and the National Institute of Mental Health have found. view more (2007-07-18)
CLIMATE CAPERS UNDER EXAMINATION - International Conference near Bremen
A new era in climate research began with the ice-core drilling in Greenland at the beginning of the nineties supplying the proof that the last Ice Age was marked by large fluctuations in temperature. Differences of up to 7°C within just a few years were not uncommon. view more (1999-10-07)
Injection reverses heart-attack damage
Injured heart tissue normally can't regrow, but researchers at Children's Hospital Boston have now laid the groundwork for regenerating heart tissue after a heart attack, in patients with heart failure, or in children with congenital heart defects. view more (2009-07-24)
Researchers block the transmission of malaria in animal tests
By disrupting the potassium channel of the malaria parasite, a team of researchers has been able to prevent the malaria parasites from forming in mosquitoes and has thereby broken the cycle of infection during recent animal tests. view more (2008-06-10)
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