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Cell Death Current Events | Cell Death News
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SLU scientists have identified the first gene regulating programmed cell death in plant embryos
A research team at the Swedish University of Agricultural Sciences, SLU, has succeeded in isolating a novel gene that regulates cell death in plant embryos. This is a world first. The team consists of scientists from the Department of Plant Biology and Forest Genetics, headed by Peter Bozhkov and Sara von Arnold. The team has discovered... view more... (2004-06-01)
Burnham Researchers Turn Cancer Friend into Cancer Foe
Burnham Institute for Medical Research today announced that scientists have created a peptide that binds to Bcl-2, a protein that protects cancer cells from programmed cell death, and converts it into a cancer cell killer. view more (2008-10-08)
Therapeutic peptide frees the protein p73 to kill tumor cells
The protein p53 suppresses tumor development by potently inducing tumor cell death, making it an obvious target for anticancer therapeutics. view more (2007-03-09)
Combination therapy reduces tumor resistance to radiation
Radiation is used to treat a variety of tumors and the response of tumors to radiation is dependent on endothelial cell death, which in turn limits oxygen delivery to the tumor, causing hypoxia and tumor cell death. view more (2007-06-08)
Tumor cells evade death through autophagy
Autophagy is a cellular process that enables cells to turnover their contents, something that they do frequently. Autophagy is initiated in tumor cells by chemotherapy and radiation, but it is not known if this contributes to tumor cell death or helps tumor cells survive the anti-cancer therapy. view more (2007-01-19)
MRC scientists advance understanding of cell death
Medical Research Council (MRC) scientists have made an important advance in understanding the biological processes involved when cells are prompted to die. view more (2009-08-14)
Sexual frustration: programmed cell death prevents plant inbreeding
Scientists have demonstrated the importance of programmed cell death in preventing inbreeding in plants, according to research published in Nature today. Researchers at the University of Birmingham School of Biosciences have found that self-incompatibility, an important mechanism in plants that prevents them fertilizing themselves with their own... view more... (2004-05-19)
Enzyme may be a key to Alzheimer's-related cell death
A Purdue University researcher has discovered that the amount of an enzyme present in neurons can affect the mechanism thought to cause cell death in Alzheimer's disease patients and may have applications for other diseases such as stroke and heart attack. view more (2009-10-08)
A potential sugar fix for tumors
Researchers at the Duke School of Medicine apparently have solved the riddle of why cancer cells like sugar so much, and it may be a mechanism that could lead to better cancer treatments. view more (2008-04-16)
Matrix fragments trigger fatal excitement
Shredded extracellular matrix (ECM) is toxic to neurons. Chen et al. reveal a new mechanism for how ECM demolition causes brain damage. The study will appear in the December 29, 2008 issue of The Journal of Cell Biology (www.jcb.org). view more (2008-12-30)
New research helps explain genetics of Parkinson's disease
A new study by Narendra et al. suggests that Parkin, the product of the Parkinson's disease-related gene Park2, prompts neuronal survival by clearing the cell of its damaged mitochondria. view more (2008-11-24)
Study by NTU professors provides important insight into apoptosis or programmed cell death
A study by Nanyang Technological University (NTU)'s Assistant Professor Li Hoi Yeung, Assistant Professor Koh Cheng Gee and their team have made an important contribution to the understanding of the process that cells go through when they die. view more (2009-07-14)
Penn researchers find targeted therapy combination overcomes treatment resistance in liver cancer
Researchers at the University of Pennsylvania School of Medicine and Abramson Cancer Center reported today at the annual meeting of the American Association for Cancer Research that combining two targeted therapies overcomes treatment resistance in liver cancer cell lines. The team is currently designing a trial to test the combination in patients. view more (2008-04-14)
Prolonged stress sparks ER to release calcium stores and induce cell death in aging-related diseases
Study shows prolonged stress sparks ER to release calcium stores and induce cell death in aging-related diseases such as atherosclerosis, diabetes and neurodegeneration. view more (2009-09-14)
UAB Study Shows Drug May Fight Biliary Cancers
Laboratory studies by University of Alabama at Birmingham (UAB) researchers have shown that the drug triphendiol (NV-196) causes cell death in pancreatic and bile duct cancer cell lines, slows tumor growth and sensitizes tumors to chemotherapy treatments. view more (2008-04-16)
NEW TECHNIQUE SHOWS DEATH OF HEART CELLS IN HEART-ATTACK PATIENTS (P 209)
In this week's issue of THE LANCET, researchers from the Netherlands describe a new imaging technique capable of pinpointing areas of cell death in the hearts of patients who have had an acute myocardial infarction (heart attack). In acute myocardial infarction, the blood supply to part of the heart is cut off. When blood flow is restored, heart... view more... (2000-07-12)
Cell death occurs in the same way in plants, animals and humans
Research has previously assumed that animals and plants developed different genetic programs for cell death. view more (2009-10-14)
Therapeutic effect of imatinib improved with addition of chloroquine
The therapeutic effects of the blockbuster leukemia drug imatinib may be enhanced when given along with a drug that inhibits a cell process called autophagy, researchers from the Kimmel Cancer Center at Jefferson reported in the Journal of Clinical Investigation. view more (2009-04-14)
Penn study finds pro-death proteins required to regulate healthy immune function
Researchers at the University of Pennsylvania School of Medicine have found that proteins known to promote cell death are also necessary for the maturation and proliferation of immune cells. view more (2007-08-13)
Refusal of suicide order: Why tumor cells become resistant
Cells with irreparable DNA damage normally induce programmed cell death, or apoptosis. However, this mechanism often fails in tumor cells so that transformed cells are able to multiply and spread throughout the body. view more (2008-06-24)
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