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Stopping unwanted cell death: Implications for drug discovery
Research published in Nature Chemical Biology reveals that three specific inhibitors of a cell death pathway, termed necroptosis, all target and inhibit RIP1 kinase, a protein that can direct cells into necrosis. view more (2008-04-14)
Future therapies for stroke may block cell death
A new therapy to re-activate silenced genes in patients who suffer from neurodegenerative diseases or stroke is being developed by researchers at the University of Illinois at Chicago and Cornell University. view more (2007-06-14)
A new line of treatment discovered for acute lymphoblastic leucemia
A study undertaken by a group of Spanish scientists, amongst which were members of the University Clinic of the University of Navarra and the Centre for Applied Medical Research (CIMA) of the same university, have recently discovered a new line of treatment for patients with acute lymphoblastic leucemia. view more (2007-02-12)
Social deprivation linked to heart attack survival
Socioeconomic deprivation has a profound effect on the risk of having a first heart attack, the chance of reaching hospital alive, and the probability of surviving the first month, finds a study in this week's BMJ. Data obtained from the Scottish Morbidity Record and General Register Office revealed that between 1986 and 1995 in Scotland, 44,465... view more... (2001-05-09)
Study identifies 5 genetic themes key to keeping stem cells in a primitive, flexible state
For more than 25 years, stem cells have been defined based on what they can become: more of themselves, as well as multiple different specialized cell types. view more (2007-06-20)
Metals could forge new cancer drug
Drugs made using unusual metals could form an effective treatment against colon and ovarian cancer, including cancerous cells that have developed immunity to other drugs, according to research at the University of Warwick and the University of Leeds. view more (2009-10-19)
Researchers Create Model of Cancer-Preventing Enzyme, Study How It Works
Proline dehydrogenase is important because it plays a role in apoptosis, the process of cell death, by enabling the creation of superoxide, a highly reactive electron-rich oxygen species. view more (2007-05-14)
Suicide The Leading Cause Of Death Among Young Adults In China (pp 813, 835)
A study in this week's issue of THE LANCET describes the incidence of suicide among people living in China, highlighting that it is the most common cause of death in young adults, three times more frequent in rural areas than urban environments, and 25% more common in women than men. A wide range of suicide rates are reported for China because... view more... (2002-03-06)
Stem cell transplantation procedure results in long-term survival for amyloidosis patients
Researchers from the Stem Cell Transplant Program and the Amyloid Treatment and Research Program at Boston University Medical Center (BUMC) have found that high-dose chemotherapy and blood stem cell transplantation can result in long-term survival for patients diagnosed with primary systemic light chain (AL) Amyloidosis. view more (2007-08-08)
2 heads are better than 1: 2 dysfunctional DNA repair pathways kill tumor cells
Individuals who inherit two mutant copies of any one of about 12 genes that make the proteins of the Fanconi Anemia (FA) pathway develop FA, which is characterized by increased incidence of cancer and bone marrow failure, among other things. view more (2007-04-13)
Forsyth scientists discover early key to regeneration
Science may be one step closer to understanding how a limb can be grown or a spinal cord can be repaired. Scientists at The Forsyth Institute have discovered that some cells have to die for regeneration to occur. view more (2006-12-13)
Serious illness among children with sickle cell disease reduced with vaccine
A vaccine introduced in 2000 has reduced by more than 90 percent the rate of a serious bacterial illness among young children with sickle cell disease (SCD), who are particularly susceptible to it. view more (2007-05-02)
No pacemakers in the brain may explain cot death
A failure to 'gasp' has long been proposed as the basis for sudden infant death syndrome, or cot death. view more (2006-02-13)
Researchers identify new, cancer-causing role for protein
The mainstay immune system protein TRAF6 plays an unexpected, key role activating a cell signaling molecule that in mutant form is associated with cancer growth, researchers at The University of Texas M. D. Anderson Cancer Center report in the Aug. 28 edition of Science. view more (2009-08-28)
'Disquieting' slow down in heart disease deaths among under 55s
The fall in deaths from heart disease among younger Britons is slowing down, pointing to a "disquieting" trend, indicates research published ahead of print in the journal Heart. view more (2007-07-19)
Cellular 'brakes' may slow memory process in aging brains
University of Florida researchers may have discovered why some brain cells necessary for healthy memory can survive old age or disease, while similar cells hardly a hairsbreadth away die. view more (2008-12-11)
LSUHSC research describes function of key protein in cancer spread
Research led by David Worthylake, PhD, Assistant Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans, may help lay the groundwork for the development of a compound to prevent the spread of cancer. view more (2009-05-22)
Death rates during hot weather start rising at relatively low temperatures
The impact of heat on death rates begins at relatively low temperatures during hot weather, finds research in the Journal of Epidemiology and Community Health. view more (2002-04-15)
OF END-OF-LIFE DECISIONS IN MEDICAL PRACTICE IN BELGIUM (FLANDERS)
Background The study presented here is the first replica of the Dutch death-certificate study on end-of-life decisions (ELDs). The main objective was to estimate the incidence of euthanasia (the administration of drugs with the explicit intention to shorten the patient’s life at the explicit request of the patient), physician-assisted... view more... (2000-11-22)
Over 80 million Americans risking early death through smoking or obesity
Over 80 million American adults are putting themselves at serious risk of long-term illness and early death through smoking, obesity, or both. view more (2006-05-12)
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