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EARLY PROMISE FOR NEW TREATMENT OF SKIN CANCER (p 525)
A preliminary study published as a research letter in this week's issue of THE LANCET suggests that the herpes virus could contribute to the treatment of malignant melanoma, the most serious form of skin cancer. Previous laboratory research has shown that a mutant herpes simplex virus (HSV1716) has improved the survival times of animals with... view more... (2001-02-14)
Cornell researchers identify a weak link in cancer cell armor
The seeming invincibility of cancerous tumors may be crumbling, thanks to a promising new gene therapy that eliminates the ability of certain cells to repair themselves. view more (2009-11-13)
Women fast catching up with men on risks of sudden death after heart attack
Women are fast catching up with men when it comes to risk of sudden death after a heart attack, reveals research in Heart. view more (2002-11-18)
Sickness records can predict employee deaths
Employees who take long spells of sick leave more than once in two years are at a higher risk of death than their colleagues with no such absence, conclude researchers in this week's BMJ. They obtained sickness absence records for 6,895 male and 3,413 female civil servants until the end of 1989 and analysed associations with death until 1999.... view more... (2003-08-12)
PINK1 protects from Parkinson's
Parkinson disease (PD) is a common neurodegenerative disease characterized by the selective loss of midbrain dopaminergic neurons. view more (2007-06-19)
Decline in lung function increases risk of death from all causes
Reduced ability of the lungs to work properly - a process accelerated by smoking - increases the risk of death from all causes, shows research in Thorax. But even giving up for a while, halts the decline, and can reduce the risk of death from all causes by around 20 per cent, the study shows. The research involved a long term study between 1959... view more... (2001-08-20)
Transcription factor protein's role in cell death, neurodegeneration and schizophrenia
Researchers at the University of Pennsylvania School of Medicine discovered that a protein called Elk-1 interacts with mitochondria, the energy storehouse of a cell, suggesting that this protein -— typically active in the nucleus — could play a role in cell death and mitochondria-related diseases such as neurodegeneration and... view more... (2006-06-08)
Research suggests targeted treatment strategies for lupus
New research provides clues about the causes of lupus symptoms and suggests specific new targeted treatment strategies, according to Nilamadham Mishra, M.D., from Wake Forest University Baptist Medical Center, in presentations this week at the American College of Rheumatology in Boston. view more (2007-11-12)
Why don't brain tumors respond to medication?
Malignant brain tumors often fail to respond to promising new medication. Researchers in Heidelberg have discovered a mechanism and a tumor marker for the development of this resistance. view more (2009-09-01)
Caesarean delivery of twins may prevent deaths
Second twins born at term are at higher risk of death due to complications during labour and delivery than first twins, but planned caesarean section may prevent such deaths, concludes a study in this week’s BMJ. view more (2002-10-30)
Upside-down world: DNA protecting protein helps cancer drug to kill cells
Some DNA repair enzymes can become double-edged swords - If they work too slowly, they can block necessary cell maintenance and contribute to cell death. view more (2009-04-28)
Outsmarting cancer - new results from novel enzyme inhibitors
Smart drugs that can break the chain of command between enzymes and the genes involved in cell division and cell death are a new way forward in tackling breast cancer, according to Dr Stephen Johnston, a consultant oncologist from The Royal Marsden Hospital, London, UK. He was speaking at a news briefing on Thursday (21 March) at the 3rd European... view more... (2002-03-19)
Cell death following blood 'reflow' injury tracked to natural toxin
Researchers at Johns Hopkins have discovered what they believe is the "smoking gun" responsible for most tissue and organ damage after a period of blood oxygen loss followed by a sudden restoration of blood oxygen flow. view more (2006-11-30)
Research shows promise for using stem cell transplantation to treat patients with severe lupus
About half of patients with severe lupus that was refractory to standard treatment and who underwent autologous stem cell transplantation to improve their immune system have substantial improvement in disease activity after several years. view more (2006-02-01)
A sticky business -- how cancer cells become more 'gloopy' as they die
The viscosity, or 'gloopiness', of different parts of cancer cells increases dramatically when they are blasted with light-activated cancer drugs, according to new images that provide fundamental insights into how cancer cells die, published in Nature Chemistry today (15 March). view more (2009-03-16)
Molecule targets and kills tumor cells, starves blood supply
A man-made chemical compound called ARC causes tumor cells to die but leaves normal cells unharmed. view more (2006-03-16)
Penn researchers identify new combination therapy that promotes cancer cell death
Researchers at the University of Pennsylvania School of Medicine identified a combination therapy as a way to sensitize resistant human cancer cells to a treatment currently being tested in clinical trials. view more (2007-07-17)
Doctors' own fear of death linked to hastening death of very sick newborns
Doctors who fear their own death say they are more prepared than other doctors to hasten death in sick newborns for whom further medical treatment is considered futile. view more (2007-02-06)
Egg's Energy Stores Key to Preserving Fertility
An immature egg's internal nutrient supply is critical to its survival, an insight that offers a new route to understanding and treating infertility due to egg death. view more (2005-10-07)
Is Bcl-2 protein a major obstacle in treating colorectal carcinoma?
Apoptosis resistance has been shown to contribute to the development of different cancer entities, such as colorectal carcinoma (CRC). view more (2008-09-24)
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