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Alzheimer's disease as a case of brake failure?
Rutgers researcher Karl Herrup and colleagues at Case Western Reserve University have discovered that a protein that suppresses cell division in brain cells effectively "puts the brakes" on the dementia that comes with Alzheimer's disease (AD). When the brakes fail, dementia results. view more (2008-06-25)
Post-mortem brain studies reveal features of mild cognitive impairment
The brains of patients with mild cognitive impairment display pathologic features that appear to place them at an intermediate stage between normal aging and Alzheimer's disease, although some patients with mild cognitive impairment develop other types of dementia. view more (2006-05-09)
Hepatitis C virus channels efforts into cell survival
Researchers at the University of Leeds have discovered a previously unknown mechanism that allows the hepatitis C virus (HCV) to remain in the body for decades. view more (2009-08-18)
Research shows NPD1 protects a key component of vision
Two papers to be published in the Early Edition online of the Proceedings of the National Academy of Sciences (PNAS) the week of July 30-August 3, 2007 report findings that demonstrate that neuroprotectin D1 (NPD1) protects against damage to retinal pigment epithelial (RPE) cells and identifies an important trigger for its production and novel... view more... (2007-07-31)
New Cancer Gene Discovered
Researchers at the OU Cancer Institute have identified a new gene that causes cancer. The ground-breaking research appears Monday in Nature's cancer journal Oncogene. view more (2008-05-09)
Hitting cell hot spot could help thwart Parkinson's disease
The latest work to 'turn off the taps' in the brain and stop a chemical being released in excess amounts - which can lead to Parkinson's Disease - will be presented at The British Pharmacological Society's Summer Meeting in Edinburgh. view more (2009-07-08)
Synthetic molecules hold promise for new family of anti-cancer drugs
Synthetic molecules designed by two Hebrew University of Jerusalem researchers have succeeded in reducing and even eliminating the growth of human malignant tissues in mice, while having no toxic effects on normal tissue. view more (2008-06-05)
Doctors may need support to cope with patient death
Doctors could benefit from support to help them cope with the trauma of patient death, says a psychologist speaking at the Death, dying & disposal conference organised by the University of Bath today. view more (2007-09-13)
Adaptation to oxygen deprivation elucidates tumor physiology
Two new studies in the March Cell Metabolism reveal a survival mechanism by which cells adapt to oxygen starvation by ratcheting down their demand. view more (2006-03-08)
Markers of inflammation and blood-clotting tied to hazards of intermittent HIV treatment
Episodic treatment of HIV/AIDS with antiretroviral drugs increases the overall risk of death when compared with continuous antiretroviral treatment (ART), but the reasons why have been unknown. view more (2008-10-22)
Sphingolipids with therapeutic ends
Sphingolipids have been known for more than 120 years but, up to recently, they were thought to be molecules that simply complied with a structural function, acting, as it were, as the building blocks of the biological membranes. view more (2007-03-05)
Cycles of cell death, proliferation key to liver cancer
Research at the University of California, San Diego (UCSD) School of Medicine shows that liver cancer is likely caused by cycles of liver cell death and renewal. view more (2006-06-23)
The American Glaucoma Foundation grants award to the University of the Basque Country
The prestigious American Glaucoma Foundation has recently awarded the research team of the Faculty of Medicine at the University of the Basque Country (EHU), led by cell biologist, Elena Vecino. This is the first time that the North American foundation has awarded a European research work. view more (2004-11-09)
UK leads race to produce world's first clinical grade stem cells
The University of Sheffield has received a £2.6m grant to create some of the world's first embryonic stem cell lines that can be used for medicinal purposes. view more (2005-03-16)
Hopes of a New Treatment Approach for Paralysis
Scientists at the Deutsches Krebsforschungszentrum (German Cancer Research Center, Heidelberg) were recently able to show in experiments with mice that a paralysis can be reversed by blocking programmed cell death. Paralysis in the form of paraplegia and quadriplegia is usually the result of traumatic spinal cord injuries, but can also be caused... view more... (2004-03-15)
Heart enlargement is a common cause of sudden death in young people (p 1881)
A seminar in this week's issue of THE LANCET highlights the frequency, diagnosis and management of hypertrophic cardiomyopathy, an unexplained thickening of the heart in young adults that has a 1% annual risk of sudden death. Dr. Perry Elliott from University College, London, UK and Professor William McKenna from The Heart Hospital, London state... view more... (2004-06-02)
A clue to core problem of neurodegenerative disease and cell death
Misfolded and damaged proteins are common to all human neurodegenerative diseases. Clumps of these aggregated proteins destroy neurons within the brain and cause disease. view more (2006-02-10)
Relationship between environmental stress and cancer elucidated
One way environmental stress causes cancer is by reducing the activity level of an enzyme that causes cell death, researchers say. view more (2007-11-06)
Variation of normal protein could be key to resistance to common cancer drug
Researchers at the Moores Cancer Center at the University of California, San Diego (UC SD) in La Jolla have found evidence explaining why a common chemotherapy drug, cisplatin, may not always work for every cancer patient. They have shown that when a variant version of a key protein that normally causes cell death is active, patients may be... view more... (2008-08-28)
Cutting calories could limit muscle wasting in later years
Chemical concoctions can smooth over wrinkles and hide those pesky grays, but what about the signs of aging that aren't so easy to fix, such as losing muscle mass? Cutting calories early could help, say University of Florida researchers who studied the phenomenon in rats. view more (2008-09-17)
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