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ETH Zurich study on salmonella self-destruction
ETH Zurich biologists, led by Professors Martin Ackermann and Wolf-Dietrich Hardt, in collaboration with Michael Doebeli of the University of British Colombia in Vancouver (CN), have been able to describe how random molecular processes during cell division allow some cells to engage in a self-destructive act to generate a greater common good,... view more... (2008-08-22)
Hat Trick for University of Leicester Plant Biologist
A University of Leicester scientist has recently received the EMBO (European Molecular Biology Organisation) Young Investigator Award, the first UK plant biologist to be awarded this prestigious international prize. view more (2004-10-29)
Weizmann Institute scientists discover a molecular security mechanism for keeping mutations in check
Everyone knows mutations - genetic mistakes in DNA, the material of heredity - are bad: The more mutations in the cell's DNA, the higher the risk of cancer developing. view more (2006-05-05)
Cell division find prompts overhaul of immune response modelling
Research at the Walter and Eliza Hall Institute into the mechanics of how two types of white blood cells grow and die is fundamentally changing the development of computer models that are used to predict how immune system cells respond to a pathogenic threat. view more (2009-07-21)
£2.5M for research that will underpin the search for new antibiotics
The grants, which are both for periods of 5 years, total £2.5M. New antibiotics are urgently needed to maintain control of disease-causing bacteria, which are becoming resistant to more and more conventional antibiotics. view more (1999-10-12)
A new link between stem cells and tumors
Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg and the Institute of Biomedical Research of the Parc Científic de Barcelona (IRB-PCB) have now added key evidence to claims that some types of cancer originate with defects in stem cells. view more (2005-09-06)
Landmark study sheds new light on human chromosomal birth defects
Using yeast genetics and a novel scheme to selectively remove a single protein from the cell division process called meiosis, a cell biologist at The Florida State University found that when a key molecular player known as Pds5 goes missing, chromosomes fail to segregate and pair up properly, and birth defects such as Down syndrome can result. view more (2009-09-17)
Flip of genetic switch causes cancers in mice to self-destruct, Stanford researchers find
Killing cancerous tumors isn't easy, as anyone who has suffered through chemotherapy can attest. But a new study in mice shows that switching off a single malfunctioning gene can halt the limitless division of tumor cells and turn them back to the path of their own planned obsolescence. view more (2007-07-31)
Cracking the egg
Sexual reproduction is not necessarily sexy (especially when scientists start analyzing it), but it is fascinating. As we all know, the basics entail bringing together an egg and a sperm, a whole lot of cell division and growth, and sooner or later a young organism that carries a mix of genes from both parents. view more (2006-10-04)
Master regulatory gene found that guides fate of blood-producing stem cells
Researchers from the University of Pennsylvania School of Medicine found that a protein called NF-Ya activates several genes known to regulate the development of hematopoietic stem cells (HSC), or blood-producing stem cells, in bone marrow. view more (2005-08-02)
Electric fields have potential as a cancer treatment
Low-intensity electric fields can disrupt the division of cancer cells and slow the growth of brain tumors, suggest laboratory experiments and a small human trial, raising hopes that electric fields will become a new weapon for stalling the progression of cancer. view more (2007-08-03)
Protein That Promotes Cancer Cell Growth Identified
Scientists at Burnham Institute for Medical Research (Burnham) have found that the Caspase-8 protein, long known to play a major role in promoting programmed cell death (apoptosis), helps relay signals that can cause cancer cells to proliferate, migrate and invade surrounding tissues. view more (2009-07-27)
Hormone clue to root growth
Plant roots provide the crops we eat with water, nutrients and anchorage. Understanding how roots grow and how hormones control that growth is crucial to improving crop yields, which will be necessary to address food security and produce better biofuels. view more (2009-07-08)
In 'Spontaneous' Liver Cancer, Researcher Sees a Cure
Adding more good news to last week's announcement that Nexavar® (sorafenib) may be the first effective treatment for advanced liver cancer, researchers at the Lombardi Comprehensive Cancer Center at Georgetown University have uncovered a new molecular mechanism that may "spontaneously" cause liver cancer. view more (2007-06-20)
Key factor in brain development revealed, offers insight into disorder
In the earliest days of brain development, the brain's first cells - neuroepithelial stem cells -- divide continuously, producing a population of cells that eventually evolves into the various cells of the fully formed brain. view more (2008-03-27)
Dormant stem cells for emergencies
Many specialized cells, such as in the skin, intestinal mucosa or blood, have a lifespan of only a few days. For these tissues to function, a steady replenishment of specialized cells is indispensable. This is the task of so-called "adult" stem cells also known as tissue stem cells. view more (2008-12-05)
A budding role for a cellular dynamo
Actin, a globular protein found in all eukaryotic cells, is a workhorse that varies remarkably little from baker's yeast to the human body. view more (2009-02-19)
Chemotherapy can be more toxic to brain cells than to cancer cells and may cause brain damage
Drugs used to treat cancer may damage normal, healthy brain cells more than the cancer cells they are meant to target. view more (2006-11-30)
Hunt for DNA amplified in cancers uncovers important target gene
Researchers at Harvard Medical School (HMS) and Massachusetts General Hospital (MGH) have discovered a new cancer-promoting role for a gene potentially involved in breast, liver, and other kinds of cancers. view more (2006-08-08)
Study identifies new tumor suppressor
A protein called HLJ1 may work as a novel tumor suppressor in non-small-cell lung carcinoma. view more (2006-06-21)
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