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Common viruses may cause cancer
In some cases, the fusion of human cells is a normal process that leads, for instance, to the formation of muscle and bone. Viral infections can also cause cell fusion, but cells fused by viruses are widely considered to be harmless because they are generally believed to die without consequences for the host. view more (2005-11-09)
Natural protein stops deadly human brain cancer in mice
Scientists from Johns Hopkins and from the University of Milan have effectively proven that they can inhibit lethal human brain cancers in mice using a protein that selectively induces positive changes in the activity of cells that behave like cancer stem cells. view more (2006-12-08)
Telomerase inhibition - a cancer therapy that is not always what it seems
Telomerase is a protein involved in cancer where it is present in 85 to 90% of all cases. Taking advantage of this fact, over the last years multiple new approaches have appeared that aim to inhibit telomerase activity as a new treatment strategy in human cancer. However, in the latest issue of the journal Oncogene scientists reveal that in some... view more... (2004-05-25)
Cincinnati Children's researchers publish findings on potential target for leukemia treatment
Cincinnati Children's Hospital Medical Center today announced the publication of pioneering research identifying the crucial role and novel mechanism of action of the protein RhoH GTPase in the development and activation of cells critical to the immune system. view more (2006-10-10)
Immune cells from patients with rheumatoid arthritis have prematurely aged chromosomes
Telomeres, structures that cap the ends of cells' chromosomes, grow shorter with each round of cell division unless a specialized enzyme replenishes them. Maintaining telomeres is thought to be important for healthy aging and cancer prevention. view more (2009-03-05)
Fatty acids and caveolin-1 are essential in liver regeneration
Liver regulates lipid, carbohydrate and protein metabolism. It also segregates a number of proteins and enzymes, and eliminates toxic substances from the organism. Liver regeneration is a mostly unknown process at a molecular level, although it is essential for the good functioning of the liver, and indispensable in order to carry out some... view more... (2006-09-19)
MIT researchers offer glimpse of rare mutant cells
MIT biological engineers have developed a new imaging system that allows them to see cells that have undergone a specific mutation. view more (2008-07-22)
Silenced gene in worm shows role in regeneration
Researchers at the University of Utah have discovered that when a gene called smedwi-2 is silenced in the adult stem cells of planarians, the quarter-inch long worm is unable to carry out a biological process that has mystified scientists for centuries: regeneration. view more (2005-11-28)
Inhibiting cell process may give cancer drug a boost
A molecule that interferes with the internal scaffolding that shapes the cell may kill cancer cells, retard the growth of tumors and give a boost to a common chemotherapy drug. view more (2006-05-04)
Gene Function Breakthrough
A breakthrough in understanding the functions of human genes has been reported by scientists working at the Wellcome Trust Biocentre at the University of Dundee. view more (2002-01-08)
Newly discovered molecular switch helps decide cell type in early embryo development
Researchers have discovered a central molecular switch in fruit fly embryos that opens new avenues for studying the causes of birth defects and cancer in humans. Writing about their study in the Aug. 12 Developmental Cell, scientists at Cincinnati Children's Hospital Medical Center determined the switch to be a main tuning mechanism for... view more... (2008-08-12)
Stem cells not the only way to fix a broken heart
Researchers appear to have a new way to fix a broken heart. They have devised a method to coax heart muscle cells into reentering the cell cycle, allowing the differentiated adult cells to divide and regenerate healthy heart tissue after a heart attack. view more (2009-07-24)
'Birth control' for centrioles
Like DNA, centrioles need to duplicate only once per cell cycle. Rogers et al. uncover a long-sought mechanism that limits centriole copying, showing that it depends on the timely demolition of a protein that spurs the organelles' replication. view more (2009-01-26)
Computation to unravel how genes are regulated and shed light on how cells become different
A closer alliance between computational and experimental researchers is needed to make progress towards one of biology's most challenging goals, understanding how epigenetic marks contribute to regulation of gene expression. view more (2008-04-11)
Gladstone scientists identify critical gene factor in heart development
Researchers at the Gladstone Institute of Cardiovascular Disease (GICD) announced they have identified a critical genetic factor in the control of many aspects of heart form and function. view more (2007-03-30)
Advanced therapy offers cure for relapsed cancer patient
Testicular cancer patients who do not respond to traditional therapy can be cured with high-dose chemotherapy and a stem cell transplant. view more (2007-07-26)
The Nobel Prize in Chemistry 2004
The Royal Swedish Academy of Sciences has decided to award the Nobel Prize in Chemistry for 2004 "for the discovery of ubiquitin-mediated protein degradation" jointly to view more (2004-10-06)
Cancer Conundrum Cracked
Cancer researchers at the University of Dundee have just turned a common cancer belief on its head saying that a group of proteins previously believed to cause cancer can also be used in the fight against cancer. Dr Neil Perkins and his team in the School of Life Sciences have identified that NF-kappaB * a group of proteins present in every cell... view more... (2004-03-25)
The clue of genomic instability in breast cancer
New research has shown, using human tissue biopsies - a hypothesis that until now could only be argued indirectly using cell cultures - that the significant increase in genomic "disorder" that is associated with breast cancer occurs in the transition between the typical hyperplasia and the in situ carcinoma, coinciding with a reduction to a... view more... (2004-09-07)
Asymmetry due to Perfect Balance
Cell membranes are like two-dimensional fluids whose molecules are distributed evenly through lateral diffusion. But many important cellular processes depend on cortical polarity, the locally elevated concentration of specific membrane proteins. view more (2007-04-26)
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