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Scientists isolate protein that may be 'boon' to medicine
Scientists at UC Santa Barbara have isolated a unique protein that appears to have a dual function and could lead to a "boon in medicine."   view more (2009-08-05)

A new step towards an AIDS vaccine
Progressive disease after HIV infection is inversely correlated with the presence of plasmacytoid dendritic cells (pDCs), a subset of the dendritic cell family and the major producers of type 1 interferon in the body.   view more (2005-10-14)

APL regulates vascular tissue identity in Arabidopsis
Plants have a conductive tissue, phloem, for transporting sugars and hormones to non-green parts after photosynthesis. Phloem has two basic cell types, enucleate sieve elements (SE) and companion cells (CC). Scientists from the University of Helsinki have developmentally analyzed the process of phloem development in Arabidopsis plant and... view more... (2003-11-13)

For children with sickle cell disease, lung disease is part of the package
Children with sickle cell disease (SCD) have a significantly sharper decline in lung function with age when compared to other children of the same race and age.   view more (2008-05-19)

How actin networks are actin'
Dynamic networks of growing actin filaments are critical for many cellular processes, including cell migration, intracellular transport, and the recovery of proteins from the cell surface.   view more (2008-01-03)

What is the function of NOD2 in colonic epithelial cells?
NOD2 is a cytosolic pattern recognition receptor similar in structure and function to Toll like receptors (TLRs). It can recognize and respond to a component found in the cell wall of bacteria, muramyl dipeptide (MDP), and has been shown to play an important role in the innate immune response of macrophages to bacterial infections.   view more (2008-10-23)

Proteasome activator enhances survival of Huntington's disease neuronal model cells
To function, each living cell needs both to build new and to degrade old or damaged proteins. To accomplish that, a number of intracellular systems work in concert to keep the cell healthy and from clogging up with damaged proteins.   view more (2007-02-28)

Can plant research lead to new insights in cancer research?
Ghent - The development of cancer is a complex process with a number of different causes. The root problem is loss of control in the cell division process. A fundamental biological process, cell division can be studied in many organisms. Researchers from the Flanders Interuniversity Institute for Biotechnology (VIB) connected with Ghent University... view more... (2005-01-10)

Adult sickle cell drug proves effective in young children
A drug used for the treatment of sickle cell anemia in adults has now been shown to cause significant improvements in very young children with the disorder.   view more (2005-09-20)

Bone marrow cell therapy may be beneficial for patients with ischemic heart disease
The injection of bone marrow cells into the heart of patients with chronic myocardial ischemia (reduced blood flow to some areas of the heart) was associated with modest improvements in blood flow and function of the left ventricle.   view more (2009-05-20)

The anti-diabetic effects of sodium tungstate revealed
The molecular mechanisms of tungstate activity in diabetes have been uncovered. Researchers writing in the open access journal BMC Genomics have identified the pathways through which sodium tungstate improves pancreatic function and beta cell proliferation.   view more (2009-08-28)

Dartmouth researchers find new protein function
A group of Dartmouth researchers has found a new function for one of the proteins involved with chromosome segregation during cell division.   view more (2009-01-09)

Early Promise Of New Treatment For Type 2 Diabetes (p 824)
Authors of a pilot study in this week's issue of THE LANCET suggest that a naturally occurring intestinal hormone could be beneficial for the future treatment of type 2 diabetes. Type 2 diabetes affects an estimated 10% of adults over 60 years of age, and has recently been reported in teenage children. Treatment for the disorder usually includes... view more... (2002-03-06)

Wnt signalling protein Dishevelled acts in the nucleus, not just in the cytoplasm
Researchers have identified that Dishevelled doesn't only function in the cytoplasm and at the cell membrane - it must also pass into the nucleus. A study published today in Journal of Biology reveals that Dishevelled, a key player in the Wnt/beta-catenin signalling pathway, has to be localised in the nucleus to perform a key aspect of its... view more... (2005-02-11)

Researchers identify new target in fight against obesity
University of Cincinnati (UC) scientists have identified a possible new target for treating obesity and diabetes.   view more (2005-09-20)

Tumor suppressor gene in flies may provide insights for human brain tumors
In the fruit fly's developing brain, stem cells called neuroblasts normally divide to create one self-renewing neuroblast and one cell that has a different fate. But neuroblast growth can sometimes spin out of control and become a brain tumor.   view more (2009-06-23)

New telomere discovery could help explain why cancer cells never stop dividing
A group working at the Swiss Institute for Experimental Cancer Research (ISREC) in collaboration with the University of Pavia has discovered that telomeres, the repeated DNA-protein complexes at the end of chromosomes that progressively shorten every time a cell divides, also contain RNA.   view more (2007-10-05)

Enzyme's second messenger contributes to cell overgrowth
Scientists at the University of California, San Diego (UCSD) School of Medicine have uncovered a novel pathway by which hormones elevated in inflammation, cancer and cell injury act on cells to stimulate their growth.   view more (2007-09-27)

Novel 'on-off switch' mechanism stops cancer in its tracks
A tiny bit of genetic material with no previously known function may hold the key to stopping the spread of cancer, researchers at Yale School of Medicine and Sichuan University in Chengdu, China report in two papers in the September 7-11 issue of Proceedings of the National Academy of Sciences.   view more (2009-09-24)

Linking 2 molecular pieces of the Alzheimer's puzzle
Researchers have uncovered a biological link between the protein whose mutation causes early-onset Alzheimer's disease (AD) and a gene variant linked to late-onset AD. The researchers said their finding could lead to new approaches to treating AD.   view more (2007-10-04)
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