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Enzyme's second messenger contributes to cell overgrowth
Scientists at the University of California, San Diego (UCSD) School of Medicine have uncovered a novel pathway by which hormones elevated in inflammation, cancer and cell injury act on cells to stimulate their growth. view more (2007-09-27)
An AIDS-related virus reveals more ways to cause cancer, Penn researchers find
Researchers at the University of Pennsylvania School of Medicine have shed new light on how Kaposi's Sarcoma-associated Herpes Virus (KSHV) subverts normal cell machinery to cause cancer. view more (2007-10-09)
Mayo Clinic researchers discover cancer cells may move via wave stimulation
Mayo Clinic researchers have uncovered a new cellular secret that may explain how certain cancers move and spread - a feature of cancers that makes treatment especially difficult. view more (2006-04-03)
Growth gene linked to cancer
Growth gene linked to cancer view more (1999-12-16)
Protein can help cells or cause cancer, Purdue researcher finds
A Purdue University scientist has discovered a key process in cell growth that can lead to the formation of tumors. view more (2009-07-08)
Hot Paper in the Biochemical Journal
DNA DAMAGE INSIGHT An exciting new paper from the Biochemical Journal regarding the phosphorylation state of LKB1 in response to ionising radiation can be viewed online as an Immediate Publication at www.BiochemJ.org (DOI: 10.1042/BJ20021284). Researchers at the University of Dundee, the University of Calgary and Tel Aviv University collaborated... view more... (2002-09-20)
Cancer stem cells spur glioma Angiogenesis, could hold key to brain tumor therapy
Stem cell-like glioma cancer cells that share many characteristics with normal stem cells propel the lethal growth of brain cancers by promoting tumor blood vessel formation, and may hold the key to treating these deadly cancers. view more (2006-08-15)
Hormone mix could cut breast cancer risk and treat symptoms of menopause
The right combination of estrogen and a selective estrogen receptor modulator (SERM), which blocks the effects of estrogen in breast tissue, could relieve menopause symptoms and cut breast cancer risk. view more (2009-10-20)
Joslin researchers uncover potential role of leptin in diabetes
A new Joslin-led study has shown that leptin, a hormone known mainly for regulating appetite control and energy metabolism, plays a major role in islet cell growth and insulin secretion. view more (2007-10-02)
Jefferson researchers uncover new evidence of prolactin's possible role in breast cancer
Scientists at the Kimmel Cancer Center at Jefferson in Philadelphia have discovered new molecular evidence of the role of the hormone prolactin in breast cancer. view more (2007-10-01)
Tumor suppressor gene in flies may provide insights for human brain tumors
In the fruit fly's developing brain, stem cells called neuroblasts normally divide to create one self-renewing neuroblast and one cell that has a different fate. But neuroblast growth can sometimes spin out of control and become a brain tumor. view more (2009-06-23)
Inhibiting cell process may give cancer drug a boost
A molecule that interferes with the internal scaffolding that shapes the cell may kill cancer cells, retard the growth of tumors and give a boost to a common chemotherapy drug. view more (2006-05-04)
Bristol Scientists Discover New Molecule That Could Prevent Tumour Growth
Scientists at Bristol University have discovered a new molecule that could prevent tumour growth. Dr Dave Bates and Dr Steve Harper in the Microvascular Research Laboratories in the Department of Physiology, working in collaboration with clinicians at Southmead Hospital, have discovered a type of vascular endothelial growth factor (VEGF) found in... view more... (2002-07-12)
Treatments have same target, different responses for lung cancer patients with genetic mutation
The gene mutation that identifies the lung cancer patients most likely to respond to the drug gefitinib (Iressa) is not associated with a response to the drug cetuximab (Erbitux). view more (2005-08-17)
Researchers discover how antibiotic inhibits bacterial growth
Researchers at the University of Illinois at Chicago, in collaboration with research teams from Pharmacia & Upjohn and Pfizer, have discovered precisely how the antibiotic linezolid inhibits bacterial growth. view more (2007-05-11)
UAB Study Shows Drug May Fight Biliary Cancers
Laboratory studies by University of Alabama at Birmingham (UAB) researchers have shown that the drug triphendiol (NV-196) causes cell death in pancreatic and bile duct cancer cell lines, slows tumor growth and sensitizes tumors to chemotherapy treatments. view more (2008-04-16)
Study reveals a reprogrammed role for the androgen receptor
The androgen receptor - a protein ignition switch for prostate cancer cell growth and division - is a master of adaptability. view more (2009-07-28)
Researchers identify new target in fight against obesity
University of Cincinnati (UC) scientists have identified a possible new target for treating obesity and diabetes. view more (2005-09-20)
Outsmarting cancer - new results from novel enzyme inhibitors
Smart drugs that can break the chain of command between enzymes and the genes involved in cell division and cell death are a new way forward in tackling breast cancer, according to Dr Stephen Johnston, a consultant oncologist from The Royal Marsden Hospital, London, UK. He was speaking at a news briefing on Thursday (21 March) at the 3rd European... view more... (2002-03-19)
Protein That Promotes Cancer Cell Growth Identified
Scientists at Burnham Institute for Medical Research (Burnham) have found that the Caspase-8 protein, long known to play a major role in promoting programmed cell death (apoptosis), helps relay signals that can cause cancer cells to proliferate, migrate and invade surrounding tissues. view more (2009-07-27)
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