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Reining in cancer - first laboratory study to show that combining novel targeted therapiesmay keep cancer cells under control
A team of Italian researchers has demonstrated in the laboratory for the first time that combining two of the newest anti-cancer targeted agents may produce a powerful new combination against breast cancer - and possibly many other cancers as well. Their findings are reported (Thursday 24 January) in the journal Annals of Oncology.* They found... view more... (2002-01-21)
Synergistic growth inhibitory effect of herbal extracts against HCC and lung cancer cells
Several herbs with diversified pharmacological properties are known to be rich sources of chemical constituents that may have potential for the treatment of several human cancers. Data from the Department of Preclinical Science, Faculty of Medicine, Thammasat University, demonstrates that the growth inhibitory activity of doxorubicin or cisplatin,... view more... (2008-04-30)
New clues about mitochondrial 'growth spurts'
Mitochondria are restless, continually merging and splitting. But contrary to conventional wisdom, the size of these organelles depends on more than fusion and fission, as Berman et al. show. Mitochondrial growth and degradation are also part of the equation. view more (2009-03-02)
No cell walls, no new cancer cells
Cancer cells, like houses, need building materials for their walls. And as with a house, the cell wall needs to be built at just the right moment to protect and allow the construction of internal components. view more (2006-08-02)
Study reveals how some molecules inhibit growth of lung cancer cells
By mapping the interlocking structures of small molecules and mutated protein "receptors" in non-small cell lung cancer (NSCLC) cells, scientists at Dana-Farber Cancer Institute and their colleagues have energized efforts to design molecules that mesh with these receptors, potentially interfering with cancer cell growth and survival. view more (2007-03-13)
Bio-engineering of blood vessels
Blood vessel prostheses work best when the biochemical and mechanical properties match reality as much as possible and when they are made of biodegradable material. To this end tissue technologists grow natural vascular wall cells, endothelial cells, in a biodegradable tube made of collagen. According to Professor Istv'¡n Vermes tissue... view more... (2002-04-16)
NYU dental professor discovers biological clock
Why do rats live faster and die younger than humans? A newly discovered biological clock provides tantalizing clues. view more (2008-04-07)
Growth factor stimulates rapid extension of key motor neurons in brain
A growth factor known to be important for the survival of many types of cells stimulates rapid extension of corticospinal motor neurons - critical brain cells that connect the cerebral cortex with the spinal cord and that die in motor neuron diseases like amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease). view more (2006-11-06)
Researchers develop gene therapy to reverse pulmonary arterial hypertension
A University of Alberta research team has discovered important new information they hope will lead to more effective treatments for pulmonary arterial hypertension (PAH)-a deadly form of high blood pressure in the pulmonary arteries caused by uncontrolled cell growth. view more (2005-06-03)
Hemangioma arteriovenous malformations or how endothelial cells escape apoptosis (programmed cell death).
Hemangiomas included several types of vascular abnormalities. The first classification of vascular abnormalities was proposed in 1982. Since angiography is becoming a common investigation, a better identification of the vascular abnormalities was possible. Hemangiomas are frequent in children and are present in 10 to 12 new born babies.... view more... (1999-09-14)
Discovery of the cell's water gate may lead to new cancer drugs
The flow of water into and out from the cell may play a crucial role in several types of cancer. Scientists at the University of Gothenburg have now found the gate that regulates the flow of water into yeast cells. view more (2009-06-17)
UC Santa Barbara scientists clarify molecular basis of interferon action
Scientists at the University of California, Santa Barbara have made a significant discovery relating to viral infections in humans. view more (2007-07-20)
Tissue rigidity promotes tumor progression
Most investigations into cancer have focused on chemical signals, but a new research study provides rare insight into how mechanical force can regulate cellular behavior. view more (2005-09-20)
Possible cause and potential treatment found for aggressive head and neck cancer
Researchers at the San Francisco VA Medical Center report that they have found a potential molecular cause for the aggressive growth and spread of human head and neck squamous cell carcinoma, a highly malignant form of cancer with a very high death rate. view more (2006-04-24)
Found: Key 'go between' in heart disease
Medical researchers at UNSW have shed light on a little-known mechanism involved in the thickening of arteries, a process associated with heart disease. view more (2006-03-15)
New role for gene that counteracts formation of tumors
The researchers, connected to Ghent University, have discovered the function of an important mediator involved in suppressing the development of tumors. view more (2005-08-26)
UK Study Suggests Possible Link Between Colorectal Cancer And Human Growth Hormone Therapy (p 273)
Authors of an observational study in this week's issue of THE LANCET highlight a possible link between human growth hormone therapy and an increased risk of colorectal cancer. The investigators comment that further evidence is required before firm conclusions can be made, and stress that there is no evidence from their study as to whether there is... view more... (2002-07-24)
Protein helps cells duplicate correctly, avoid becoming cancer
A Purdue University researcher has discovered that the absence of certain proteins needed for proper cell duplication can lead to cancer. view more (2009-10-06)
Algae provide new clues to cancer
A microscopic green alga helped scientists at the Salk Institute for Biological Studies identify a novel function for the retinoblastoma protein (RB), which is known for its role as a tumor suppressor in mammalian cells. view more (2006-10-13)
Pumpkin skin may scare away germs
The skin of that pumpkin you carve into a Jack-o'-Lantern to scare away ghosts and goblins on Halloween contains a substance that could put a scare into microbes that cause millions of cases of yeast infections in adults and infants each year. view more (2009-10-29)
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