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A molecular map for aging in mice
Researchers at the National Institute of Aging and Stanford University have used gene arrays to identify genes whose activity changes with age in 16 different mouse tissues.   view more (2007-11-29)

MicroRNA gene that regulates lifespan found by Yale scientists
Genes that control the timing of organ formation during development also control timing of aging and death, and provide evidence of a biological timing mechanism for aging, Yale researchers report in the journal Science.   view more (2005-12-23)

Test detects molecular marker of aging in humans
In 2004, researchers at the University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center announced a crucial discovery in the understanding of cellular aging.   view more (2009-06-16)

Aging boosts chances that a family line will be long-lived
Scientists have puzzled over just why organisms evolved aging as a strategy, and now there appears to be an answer. Allowing one individual to carry all the cellular damage inflicted over time, rather than dividing it between two organisms during reproduction, increases the chances that the individual's line will continue to reproduce for many... view more... (2007-03-14)

Reduced mitochondrial function important mechanism in aging
Scientists at the Karolinska Institute have found that changes in the "powerhouse" of cells, the mitochondria, play a key role in aging. The findings are being published in this week's issue of the journal Nature. Mitochondria, which provide energy to cells, have their own set of DNA. Mutations of mitochondrial DNA increase with age,... view more... (2004-05-27)

Common weed could provide clues on aging and cancer
A common weed and human cancer cells could provide some very uncommon details about DNA structure and its relationship with telomeres and how they affect cellular aging and cancer, according to a team led by scientists from Texas A&M University and the University of Cincinnati (UC).    view more (2009-10-27)

Secret of eternal youth may be in reptiles
Jo'£o Pedro Magalh'£es, researcher in the Biology of Aging, suggests, in work published in the June edition of the magazine "Experimental Gerontology" and entitled "The evolution of mammalian aging", that the study of certain species of reptiles and amphibians that apparently do not age could lead to discoveries about aging. For this... view more... (2002-06-18)

Evolutionary conservation of a mechanism of longevity from worms to mammals
Though the study of aging in the nematode model organism C. elegans has provided much insight into this complex process, it is not yet clear whether genes involved in aging in the worm have a similar role in mammals.   view more (2005-10-05)

Effects of aging in stem cells
There is little disagreement that the body's maintenance and repair systems deteriorate with age, even as there is plenty of disagreement as to why.   view more (2007-07-24)

Animal study suggests inadequate sleep may exacerbate cellular aging in the elderly
Researchers at the University of Pennsylvania School of Medicine have shown that the unfolded protein response, which is a reaction to stress induced by sleep deprivation, is impaired in the brains of old mice.   view more (2008-06-30)

Scientists Unlock Possible Aging Secret in Genetically Altered Fruit Fly
Brown University researchers have identified a cellular mechanism that could someday help fight the aging process.   view more (2009-01-23)

Cutting calories slightly can reduce aging damage
A lifelong habit of trimming just a few calories from the daily diet can do more than slim the waistline-a new study shows it may help lessen the effects of aging.   view more (2006-05-09)

Suppressing a gene in mice prevents heart from aging, preserves its function
Scientists prevented age-related changes in the hearts of mice and preserved heart function by suppressing a form of the PI3K gene, in a study reported in Circulation: Journal of the American Heart Association.   view more (2009-10-13)

Researchers identify protein-telomere interactions that could be key in treating cancer
A team of researchers from The Wistar Institute have shown that a large non-coding RNA in mammals and yeast plays a central role in helping maintain telomeres, the tips of chromosomes that contain important genetic information and help regulate cell division.   view more (2009-09-01)

UF scientists reveal how dietary restriction cleans cells
Reduce, recycle and rebuild is as important to the most basic component of the human body, the cell, as it is to the environment.   view more (2007-08-24)

Drug commonly used to treat bipolar disorder dramatically increases lifespan in worms
Nematode worms treated with lithium show a 46 percent increase in lifespan, raising the tantalizing question of whether humans taking the mood affecting drug are also taking an anti-aging medication.   view more (2007-10-31)

Xie Lab Demonstrates Dual Intrinsic and Extrinsic Control of Stem Cell Aging
The Stowers Institute's Xie Lab has published recent findings that reveal some of the factors underlying the aging of stem cells.   view more (2007-10-11)

Tiny roundworm's telomeres help scientists to tease apart different types of aging
The continual and inevitable shortening of telomeres, the protective "caps" at the end of all 46 human chromosomes, has been linked to aging and physical decline.   view more (2005-08-08)

Role for CISD2 gene in human disease and lifespan control
In the May 15th issue of G&D, Dr. Ting-Fen Tsai (The National Yang-Ming University, Taiwan) and colleagues present a new animal model of human Wolfram Syndrome, and effectively link CISD2 gene function, mitochondrial integrity and aging in mammals.   view more (2009-05-15)

Retinol lotion reduces the fine wrinkles from natural aging of skin
Lotions containing retinol improve the appearance of skin that has become wrinkled through the normal aging process, not just skin that has been damaged by exposure to the sun.   view more (2007-05-22)
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