Cellular Pathway Current Events | Cellular Pathway News
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Atherosclerosis studied at the cellular level
A McMaster University study on atherosclerosis will be featured on the cover of the December issue of the high impact American Heart Association scientific journal, Arteriosclerosis, Thrombosis and Vascular Biology. view more (2005-12-02)
An unexpected link between coronavirus replication and protein secretion in infected cells
Coronavirus replication is critically linked to two factors within the early secretory pathway, according to new findings by a team of Dutch researchers that are published June 13th in the open-access journal PLoS Pathogens. view more (2008-06-13)
Embryonic patterning makes the feathers fly
How the chicken got its feathers in the right place is not a Rudyard Kipling "Just So" story, but an illustration of how simple causes can stack up into complicated results. For a chicken, it's the difference between having feathers arranged in spots or stripes. For biologists at the University of Southern California and mathematicians... view more... (2006-12-11)
Unraveling how cells respond to low oxygen
Gary Chiang, Ph.D., and colleagues at Burnham Institute for Medical Research (Burnham) have elucidated how the stability of the REDD1 protein is regulated. view more (2009-08-06)
New pathway could present an intervention point for cancer treatment
A new cellular pathway leads to destruction of a protein that promotes growth of breast, prostate and similar cancers and could provide a new avenue through which to pursue treatment of such diseases. view more (2006-01-27)
Long-term memory controlled by molecular pathway at synapses
Harvard University biologists have identified a molecular pathway active in neurons that interacts with RNA to regulate the formation of long-term memory in fruit flies. view more (2006-01-13)
A new line of treatment discovered for acute lymphoblastic leucemia
A study undertaken by a group of Spanish scientists, amongst which were members of the University Clinic of the University of Navarra and the Centre for Applied Medical Research (CIMA) of the same university, have recently discovered a new line of treatment for patients with acute lymphoblastic leucemia. view more (2007-02-12)
2 heads are better than 1: 2 dysfunctional DNA repair pathways kill tumor cells
Individuals who inherit two mutant copies of any one of about 12 genes that make the proteins of the Fanconi Anemia (FA) pathway develop FA, which is characterized by increased incidence of cancer and bone marrow failure, among other things. view more (2007-04-13)
Molecular pathway linked to breast cancer recurrence
A study published in the September issue of Cancer Cell provides new evidence for a genetic pathway that is involved in the recurrence of breast cancer and identifies a potential target for development of new anticancer therapeutics. view more (2005-09-20)
'Cross-talk' mechanism contributes to colorectal cancer
Researchers at the University of Wisconsin-Madison School of Medicine and Public Health have identified a molecular mechanism that allows two powerful signaling pathways to interact and begin a process leading to colorectal tumors. view more (2009-11-16)
Study identifies how tamoxifen stimulates uterine cell growth and cancer
UCSF researchers have identified a new "feed-forward" pathway linking estrogen receptors in the membrane of the uterus to a process that increases local estrogen levels and promotes cell growth. view more (2009-07-06)
Researchers identify protein pathway involved in Parkinson disease development
Scientists have found a novel signaling pathway in cells that is altered by genetic mutations recently identified in Parkinson disease development. view more (2007-06-19)
Cellular pathway yields potential new weapon in vaccine arsenal
When a cell has to destroy any of its organelles or protein aggregates, it envelopes them in a membrane, forming an autophagosome, and then moves them to another compartment, the lysosome, for digestion. Two years ago, Rockefeller University assistant professor Christian Münz showed that this process, called autophagy, sensitizes cells for... view more... (2006-12-27)
A potential approach to treatment of hepatitis B virus infection
Eukaryotic cells employ multiple strategies of checkpoint signaling and DNA repair mechanisms to monitor and repair damaged DNA. view more (2008-09-10)
MIT applies engineering approach to studying biological pathways
An MIT team has used an engineering approach to show that complex biological systems can be studied with simple models developed by measuring what goes into and out of the system. view more (2008-02-07)
The secret to long life
What controls lifespan? An intriguing new twist is emerging from the work of Professor Heinz Osiewacz (Frankfurt) using a short-lived fungus. He has discovered that when there is a mutation in the gene, Grisea, that controls copper uptake into cells, the fungus can live 60% longer than their normal wild-types. Why is this? Professor Osiewacz... view more... (2001-04-04)
Second low-oxygen pathway hints at cancer, cardiovascular disease physiology
Researchers at the University of Pennsylvania School of Medicine have identified a second molecular pathway that promotes cell survival in low-oxygen conditions. view more (2006-02-17)
Reversal of role for a viral protein associated with the development of lymphoma
A protein previously thought to merely hinder the activity of a key cellular protein linked to cancer cell death, now appears to mimic the cellular signaling of that protein; potentially leading to the development of lymphoma. view more (2005-08-23)
Mayo Clinic Cancer Center — individualizing treatment for multiple myeloma patients
Researchers at Mayo Clinic Cancer Center, in cooperation with industry partners, have, for the first time, identified tumor specific alterations in the cellular pathway by which the multiple myeloma drug bortezomib (Velcade) works, and they have identified nine new genetic mutations in cancer cells that should increase a patient's chance of... view more... (2006-12-11)
Estrogen protects liver after traumatic injury
Researchers have identified the receptor pathway used by estrogen to decrease liver injury after trauma and hemorrhage. view more (2007-04-02)
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