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Scripps research scientists observe human neurodegenerative disorder in fruit flies
A team of scientists from The Scripps Research Institute, Katholeike Universiteit Leuven, and the University of Antwerp, Belgium, among other institutions, has created a genetically modified fruit fly that mimics key features of Charcot-Marie-Tooth disease, a common neurodegenerative disorder that strikes about one out of every 2,500 people in the... view more... (2009-06-25)

Research simplifies diagnosis of Charcot-Marie-Tooth disease
Hereditary Charcot-Marie-Tooth (CMT) disease strikes 1 in 2500 people. Researchers from the Flanders Interuniversity Institute for Biotechnology (VIB) connected to the University of Antwerp are now demonstrating that mutations in mitofusin 2 are the major cause of CMT2, a specific type of the disease.   view more (2006-07-25)

Fruit fly steps in to fight human disease
"By putting mutant genes from human patients into fruit flies, we've created the first ever fly model for this kind of neuromuscular disease," says Albena Jordanova.   view more (2009-06-23)

Defective movement of cell's power plants implicated in commom inherited neurological disorder
Contrary to previous thinking, the inefficient movement of cell's "power plants" -- the mitochondria -- within a cell, rather than their low energy production, may be a contributing factor in the development of Charcot-Marie-Tooth disease (CMT), new research shows.   view more (2007-01-17)

Discovery of new gene for rare nerve disease may help doctors understand more common illnesses
A multi-national research team that includes a Saint Louis University neurologist has discovered a gene mutation that causes a rare form of Charcot-Marie-Tooth disease, an inherited progressive nerve disorder.   view more (2006-01-31)

A new mouse model provides insight into genetic neurological disorders
Neurosensory diseases are difficult to model in mice because their symptoms are complex and diverse. The genetic causes identified are often lethal when transferred to a mouse.   view more (2009-05-26)

Mother's vitamin D status during pregnancy will affect her baby's dental health
Low maternal vitamin D levels during pregnancy may affect primary tooth calcification, leading to enamel defects, which are a risk factor for early-childhood tooth decay.   view more (2008-07-07)

The downside of microtubule stability
Stalled microtubules might be responsible for some cases of the neurological disorder Charcot-Marie-Tooth (CMT) disease.   view more (2009-06-15)

Unlocking the secrets of tooth enamel could improve dental care products
Materials scientists in the UK are using their expertise to probe the chemical and mechanical properties of the enamel surface of the human tooth. The research is shedding new light on how tooth enamel responds to attack by acids and could lead to new dental care products that help teeth to replace mineral that has been lost. The work is being... view more... (2002-05-28)

Mutation may cause inherited neuropathy
Mutations in a protein called dynein, required for the proper functioning of sensory nerve cells, can cause defects in mice that may provide crucial clues leading to better treatments for a human nerve disorder known as peripheral neuropathy, which affects about three percent of all those over age 60.   view more (2007-12-26)

Postmenopause and periodontal disease
Postmenopausal women may significantly reduce tooth loss by controlling their periodontal disease, according to a study in the Journal of Periodontology.   view more (2005-07-25)

New clues about mitochondrial 'growth spurts'
Mitochondria are restless, continually merging and splitting. But contrary to conventional wisdom, the size of these organelles depends on more than fusion and fission, as Berman et al. show. Mitochondrial growth and degradation are also part of the equation.   view more (2009-03-02)

Novelty seekers have a ‘sweet tooth’
It has long been known that more adventurous and novelty-seeking animals also possess a `sweet tooth`. It now seems that humans may show the same characteristic.   view more (2002-02-27)

Reconstructing mandibular defects with bioengineered tooth and bone
Current strategies for jaw reconstruction require multiple procedures, first to repair the bone defect to offer sufficient support, and then to place the tooth implant.   view more (2008-04-07)

Mouse to man: The story of chromosomes
The complete sequencing of human chromosome 17 and mouse chromosome 11 offers unique insights into the evolution of the genome of higher mammals.   view more (2006-04-20)

Study: Sports drink consumption can cause tooth erosion
While sipping on sports drinks all day may provide an energy boost, this popular practice is also exposing people to levels of acid that can cause tooth erosion and hypersensitivity, NYU dental researchers have found.   view more (2009-04-06)

Dental stem cells have been characterized for tooth tissue engineering
Today, during the 84th General Session of the International Association for Dental Research, a team from The Forsyth Institute (Boston, MA, USA) will report that their research has demonstrated that mixed populations of cultured post-natal tooth bud cells can be used to generate bioengineered dental tissues.   view more (2006-06-29)

PRESS INVITE: Marie Curie Fellowships showcased at CERN
CERN becomes a showcase for European Union (EU) research on 3-4 October when it hosts a workshop for EU-funded Marie Curie fellows working in various fields of physics and technology. The Marie Curie scheme gives young researchers from around the continent the mobility to go to wherever Europe`s best facilities in their chosen field happen to be,... view more... (2002-10-01)

Premature tooth loss can affect oral health for years to come
The prospect of exchanging a tooth for that coveted reward from the tooth fairy often has kids wiggling teeth with vigor, but what happens when a primary or permanent tooth is lost prematurely due to trauma?   view more (2008-05-23)

Tooth loss, dementia may be linked, JADA study suggests
Tooth loss may predict the development of dementia late in life, according to research published in the October issue of The Journal of the American Dental Association (JADA).   view more (2007-10-11)
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