Chemical Pathway Current Events | Chemical Pathway News
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A new weapon in the fight against obesity and diabetes
A study appearing November 5 in the journal Cell Metabolism demonstrates that a synthetic new chemical entity protects against diet-induced obesity, improves glucose tolerance and insulin sensitivity and enhances exercise endurance by enhancing fat utilization in certain target tissues. view more (2008-11-05)
2 heads are better than 1: 2 dysfunctional DNA repair pathways kill tumor cells
Individuals who inherit two mutant copies of any one of about 12 genes that make the proteins of the Fanconi Anemia (FA) pathway develop FA, which is characterized by increased incidence of cancer and bone marrow failure, among other things. view more (2007-04-13)
Nature's process for nitrogen fixation caught in action
Nitrogen gas is converted to ammonia fertilizer by a chemical process that involves high temperature and high pressure. Nature does the same thing at ambient temperature and pressure. The process, called nitrogen fixation, is essential to life as it provides nutrients to plant life. view more (2006-11-10)
The secret to long life
What controls lifespan? An intriguing new twist is emerging from the work of Professor Heinz Osiewacz (Frankfurt) using a short-lived fungus. He has discovered that when there is a mutation in the gene, Grisea, that controls copper uptake into cells, the fungus can live 60% longer than their normal wild-types. Why is this? Professor Osiewacz... view more... (2001-04-04)
Embryonic patterning makes the feathers fly
How the chicken got its feathers in the right place is not a Rudyard Kipling "Just So" story, but an illustration of how simple causes can stack up into complicated results. For a chicken, it's the difference between having feathers arranged in spots or stripes. For biologists at the University of Southern California and mathematicians... view more... (2006-12-11)
A pathway towards cures for Parkinson`s and cancer
Researchers studying the Hedgehog signaling pathway have identified small molecules that could form the foundations of exciting new treatments for Parkinson's disease and certain cancers. New research published in Journal of Biology - the open access journal for exceptional research - has identified small molecules that are able to stimulate or... view more... (2002-11-01)
Xie Lab demonstrates the role of microRNA pathway
Ting Xie, Ph.D., Associate Investigator, and Zhigang Jin, Ph.D., Postdoctoral Research Associate in the Xie Lab, have published results showing that the microRNA pathway is essential for controlling self-renewal of germline stem cells and somatic stem cells in the Drosophila ovary. view more (2007-02-16)
Study identifies how tamoxifen stimulates uterine cell growth and cancer
UCSF researchers have identified a new "feed-forward" pathway linking estrogen receptors in the membrane of the uterus to a process that increases local estrogen levels and promotes cell growth. view more (2009-07-06)
BioImage A/S Signs Research Agreement with Organon
BioImage A/S announced today, that it has signed a research agreement with Organon. The agreement outlines the use of BioImage's Redistribution® assays for pathway profiling of selected lead compounds, produced by Organon's discovery projects at its research and development facilities in Oss, the Netherlands. view more (2004-09-07)
Unraveling how cells respond to low oxygen
Gary Chiang, Ph.D., and colleagues at Burnham Institute for Medical Research (Burnham) have elucidated how the stability of the REDD1 protein is regulated. view more (2009-08-06)
New small RNAs found
Dr. Kathleen Collins and a graduate researcher in her lab at UC Berkeley have identified a second RNAi pathway in Tetrahymena thermophilia - introducing a heretofore unprecedented layer of complexity to small RNA biology in unicellular organisms. view more (2005-12-16)
Gene expression profiling of dengue virus infection in cell lines and patients
Researchers at the Novartis Institute for Tropical Diseases and the Genome Institute of Singapore have identified new host genes associated with dengue virus infection, which may open new avenues to developing a drug to treat the disease. view more (2007-11-07)
Study shows big power of small RNAs, not just proteins, in halting cancer
Cold Spring Harbor Laboratory (CSHL) researchers led by Lin He, Xingyue He, and Professor and Howard Hughes Medical Investigator (HHMI) Greg Hannon have identified a family of micro RNAs (miRNAs) that enable a critical tumor suppressor network, called the p53 pathway, to fight cancer growth. view more (2007-06-07)
A new line of treatment discovered for acute lymphoblastic leucemia
A study undertaken by a group of Spanish scientists, amongst which were members of the University Clinic of the University of Navarra and the Centre for Applied Medical Research (CIMA) of the same university, have recently discovered a new line of treatment for patients with acute lymphoblastic leucemia. view more (2007-02-12)
Researchers describe 'implausible' chemistry that produces herbicidal compound
A soil microbe that uses chemical warfare to fight off competitors employs an unusual chemical pathway in the manufacture of its arsenal, researchers report, making use of an enzyme that can do what no other enzyme is known to do: break a non-activated carbon-carbon bond in a single step. view more (2009-06-11)
Controlling for size may also prevent cancer
Scientists at Johns Hopkins recently discovered that a chemical chain reaction that controls organ size in animals ranging from insects to humans could mean the difference between normal growth and cancer. view more (2007-09-21)
Scientists link genetic pathway to development of hearing
Scientists are one step closer to understanding the genetic pathway involved in the development of hearing. view more (2005-08-19)
'Cross-talk' mechanism contributes to colorectal cancer
Researchers at the University of Wisconsin-Madison School of Medicine and Public Health have identified a molecular mechanism that allows two powerful signaling pathways to interact and begin a process leading to colorectal tumors. view more (2009-11-16)
Schizophrenia linked to dysfunction in molecular brain pathway activated by marijuana
Alterations in a molecular brain pathway activated by marijuana may contribute to the cognitive symptoms of schizophrenia, according to a report in the July issue of Archives of General Psychiatry, one of the JAMA/Archives journals. view more (2008-07-08)
Lithium and bone healing
Researchers have described a novel molecular pathway that may have a critical role in bone healing and have suggested that lithium, which affects this pathway, has the potential to improve fracture healing. view more (2007-07-31)
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