Breast MRI helps predict chemotherapy's effectiveness
Magnetic resonance imaging (MRI) provides an indication of a breast tumor's response to pre-surgical chemotherapy significantly earlier than possible through clinical examination, according to a new study published online in the journal Radiology. View More (2012-05-23)
Accelerated chemotherapy given before surgery benefits patients with muscle-invasive bladder cancer
For some patients with muscle-invasive bladder cancer, treatment may begin before they undergo cystectomy, or surgical removal of the bladder. View More (2012-05-18)
Chemotherapy's effect on overall survival seems to increase based on tumor size
The most recent research released in June's Journal of Thoracic Oncology indicates there might be a positive correlation between tumor size and adjuvant platinum based chemotherapy in surgically resected patients with node negative non-small cell lung cancer. View More (2012-05-16)
'Fertilizing' bone marrow helps answer why some cancers spread to bones
Researchers found that administering a common chemotherapy drug before bone tumors took root actually fertilized the bone marrow, enabling cancer cells, once introduced, to seed and grow more easily. View More (2012-05-15)
Genetic predictor of breast cancer response to chemotherapy
Chemotherapy is a major first line defense against breast cancer. However a patient's response is often variable and unpredictable. View More (2012-05-11)
HPV-positive throat cancer patients respond better to radiotherapy alone than HPV-negative patients
New findings from a large Danish database of cancer patients suggest that, even though the human papilloma virus (HPV) can trigger throat cancer, patients who are HPV-positive and are light smokers, or don't smoke at all, have a good response to treatment using radiotherapy alone, without the addition of chemotherapy with its consequent toxic side-effects. View More (2012-05-10)
Block its recycling system, and cancer kicks the can, according to new Penn study
All cells have the ability to recycle unwanted or damaged proteins and reuse the building blocks as food. But cancer cells have ramped up the system, called autophagy, and rely on it to escape damage in the face of chemotherapy and other treatments. View More (2012-05-09)
RANK protein promotes the initiation, progression and metastasis of human breast cancer
Researchers from the Bellvitge Biomedical Research Institute (IDIBELL) have shown that overactivation of the RANK signalling pathway promotes the initiation, progression and metastasis of tumours in human breast epithelial cells by dedifferentiation of breast cells to stem cells. View More (2012-04-25)
Moffitt Cancer Center Researchers Find Cancer Therapies Affect Cognitive Functioning among Breast Cancer Survivors
Researchers at Moffitt Cancer Center and colleagues at the University of South Florida and University of Kentucky have found that breast cancer survivors who have had chemotherapy, radiation or both do not perform as well on some cognitive tests as women who have not had cancer. View More (2012-04-20)
Good vibrations in fight against cancer
Medicine-toting nanochains slip into tumors and explode a chemotherapy drug into hard-to-reach cores of cancer, engineers and scientists at Case Western Reserve University report. View More (2012-04-18)
New analysis helps guide use of erlotinib in advanced non-small cell lung cancer
Patients with advanced non-small cell lung cancer should only receive treatment with the drug erlotinib before receiving standard chemotherapy if their tumor is known to harbor EGFR mutations, researchers report at the 3rd European Lung Cancer Conference in Geneva, Switzerland. View More (2012-04-18)
Live imaging shows response to cancer drugs can be boosted by altering tumor microenvironment
It should be possible to significantly improve the response of common cancers to existing "classical" chemotherapy drugs, say scientists at Cold Spring Harbor Laboratory (CSHL), by introducing agents that alter the interaction of cancer cells with their immediate surroundings, called the tumor microenvironment. View More (2012-04-17)
Biomarker family found for chemo resistant breast cancers
Biomarkers which could help to predict resistance to chemotherapy in breast cancer patients have been identified by researchers from the University of Hull, UK. View More (2012-04-13)
Normalizing tumor blood vessels improves delivery of only the smallest nanomedicines
Combining two strategies designed to improve the results of cancer treatment - antiangiogenesis drugs and nanomedicines - may only be successful if the smallest nanomedicines are used. View More (2012-04-10)
Scientists identify major source of cells' defense against oxidative stress
Both radiation and many forms of chemotherapy try to kill tumors by causing oxidative stress in cancer cells. New research from USC on a protein that protects cancer and other cells from these stresses could one day help doctors to break down cancer cells' defenses, making them more susceptible to treatment. View More (2012-04-09)
Trials show promise of human virus to treat head and neck cancer patients
A naturally-occurring harmless human virus may be able to boost the effects of two standard chemotherapy drugs in some cancer patients, according to early stage trial data published today in Clinical Cancer Research. View More (2012-04-04)
Vaccine yielded encouraging long-term survival rates in certain patients with NSCLC
Long-term follow-up of a phase II clinical trial showed encouraging survival in some patients with stage 3B/4 non-small cell lung cancer treated with belagenpumatucel-L, a therapeutic vaccine. View More (2012-04-04)
Feinstein Institute scientists present data about glioblastoma at AACR Annual Meeting
Scientists from the Feinstein Institute for Medical Research will present three abstracts about Glioblastoma multiforme (GBM), the most common and deadly adult brain cancer, at the American Association for Cancer Research (AACR) Annual Meeting to be held from Saturday through Wednesday (March 31- April 4) in Chicago, IL. View More (2012-04-04)
Early PET response to neoadjuvant chemo predicts increased survival in sarcoma patients
An early Positron Emission Tomography (PET) response after the initial cycle of neoadjuvant chemotherapy can be used to predict increased survival in patients with soft tissue sarcomas. View More (2012-04-03)
Mayo Clinic: Nutritional supplement works against some pancreatic cancer cells in mice
The dietary supplement gamma-linoleic acid can inhibit the growth of a subset of pancreatic cancer cells and selectively promote cancer cell death in mice, a Mayo Clinic study has found. View More (2012-04-03)
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