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Chemotherapy after surgery extends survival for patients with advanced endometrial cancer
A new study has shown for the first time that giving two chemotherapy drugs to women with advanced endometrial cancer after surgery reduced the risk of recurrence by 29% and extended survival by 32% compared with women who received whole abdominal irradiation. view more (2005-12-06)
New treatment shows promise against recurrent gynecologic cancers
Recurrent and metastatic endometrial and ovarian cancers can be notoriously difficult to treat: They have spread to other organs and typically have developed resistance to chemotherapy; and patients already heavily treated with chemotherapy may not be able to endure more chemo. view more (2009-04-22)
Chemotherapy for breast cancer is associated with disruption of sleep-wake rhythm in women
A study in the Sept.1 issue of the journal Sleep shows that the sleep-wake activity rhythms of breast cancer patients are impaired during the administration of chemotherapy. view more (2009-09-01)
Resistance to chemotherapy in lung cancer, optimizing flu vaccination strategies
Lung cancer is the most common cause of cancer-related death worldwide, in part because these tumors often are or become resistant to chemotherapy. view more (2006-10-03)
Chemotherapy with gemcitabine delays progression of operable pancreatic cancer
Giving pancreatic cancer patients the chemotherapy drug gemcitabine after surgery delays progression of the disease by about six months, according to new research by Japanese scientists. view more (2007-09-27)
Trial Supports Use of Marker to Predict How Pancreatic Cancer Patients Do After Surgery, Jefferson Surgeon Finds
A team of researchers, led by surgeons at the Kimmel Cancer Center at Jefferson in Philadelphia, has found further evidence supporting the ability of a protein to predict how well a patient with advanced pancreatic cancer will do after surgery, chemotherapy and radiation. view more (2007-06-25)
Study aims to find which breast cancer patients need chemotherapy
Most postmenopausal women with small breast tumors don't need chemotherapy to reduce their recurrence risk after lumpectomy. view more (2007-03-13)
First antisense drug provides benefit to subset of chronic lymphocytic leukemia patients
The first "antisense" drug to be tested in chronic lymphocytic leukemia (CLL) shows benefit in a phase III clinical trial for a specific subset of patients-those who are still sensitive to a chemotherapy drug often used to treat this cancer. view more (2007-02-15)
U-M study finds voice box can be preserved, even with the largest cancers
Some patients with large tumors on their larynx can preserve their speech by opting for chemotherapy and radiation over surgery to remove the voice box. view more (2009-06-26)
Low-dose chemotherapy plus antiangiogenesis drug has activity in advanced breast cancer
Chemotherapy given in low, frequent doses - a novel strategy called "metronomic" delivery - achieved partial shrinkage of disease in some advanced breast cancer patients when given concurrently with an angiogenesis inhibitor. view more (2005-12-09)
Tailored dosage of chemotherapy effective in treating breast cancer
By tailoring the dosage of chemotherapy to each individual patient, the treatment of breast cancer could be improved considerably. This is shown in a dissertation by Uppsala researcher Henrik Lindman at Uppsala University in Sweden. The method has proven to yield excellent results in clinical tests. The dissertation reports that an alternative way... view more... (2003-12-16)
Finding of a new molecular marker of resistance to chemotherapy in breast cancer
A collaborative study between the IDIBAPS—Hospital Clínic of Barcelona and the Hospital del Mar de Barcelona permits to establish a predictive factor in the resistance to chemotherapy in breast cancer and to establish possible therapeutic targets for the improvement of this treatment. view more (2006-06-29)
Surgery not necessary for most late-stage colorectal cancers
A new study shows that a large majority of patients who present with advanced colorectal cancer that has spread to other organs (stage IV) don't require immediate surgery to remove the primary tumor in the colon. view more (2009-06-01)
Complete response with oblimersen combination improves survival of CLL patients
Relapsed chronic lymphocytic leukemia (CLL) patients who had a complete response to combination therapy that included the drug oblimersen survived significantly longer than patients treated with chemotherapy alone, a team led by researchers at The University of Texas M. D. Anderson Cancer Center reports at the 49th Annual Meeting of the American... view more... (2007-12-10)
Melanoma treatment options 1 step closer
A targeted chemotherapy for the treatment of skin cancer is one step closer, after a team of University of Alberta researchers successfully synthesized a natural substance that shows exceptional potential to specifically treat this often fatal disease. view more (2009-10-21)
How does Fu-Zheng-Jie-Du-Decoction act on PTEN expression in hepatocellular carcinoma?
Many hepatocellular carcinoma (HCC) patients in China may be treated with Traditional Chinese medicine (TCM). Some say it works, others doubt its effectiveness. These stated that a research group in China had found TCM can down-regulate the expression of PTEN in HCC, which may suppress tumor cell growth and regulate tumor cell invasion and... view more... (2008-01-17)
Nanoparticles carry chemotherapy drug deeper into solid tumors
A new drug delivery method using nano-sized molecules to carry the chemotherapy drug doxorubicin to tumors improves the effectiveness of the drug in mice and increases their survival time. view more (2007-06-27)
Bevacizumab found to improve survival for patients with advanced breast cancer
Inhibiting the growth of blood vessels that supply tumors slows the progression of metastatic breast cancer according to results of a large clinical trial of Avastin, an anti-angiogenic therapy. view more (2007-12-27)
Radiation preferred over surgery for patients with some stages of lung cancer
After an initial chemotherapy treatment, radiation may be a better choice than surgery for patients with stage IIIA non-small-cell lung cancer, according to a randomized controlled trial published in the March 21 Journal of the National Cancer Institute. view more (2007-03-21)
Poor prognosis linked to BRCA1 mutations - but may be improved by chemotherapy
Breast cancer patients have a lower chance of long-term survival if they carry an inherited mutation in the BRCA1 gene, according to research published in Breast Cancer Research this week. However, the poor prognosis associated with the mutated gene is mitigated by chemotherapy. The breast cancer susceptibility genes, BRCA1 and BRCA2, were... view more... (2003-10-20)
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