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New image analysis techniques to monitor how breast tumours respond to drugs
New techniques that might allow magnetic resonance imaging (MRI), to be used to give doctors subtle information about a tumour’s physiology and how it reacts to drug therapy are being developed.   view more (2001-12-18)

Nanoparticles carry chemotherapy drug deeper into solid tumors
A new drug delivery method using nano-sized molecules to carry the chemotherapy drug doxorubicin to tumors improves the effectiveness of the drug in mice and increases their survival time.   view more (2007-06-27)

HtrA1 and resistance to chemotherapy in ovarian and gastric cancers
While many cancer patients initially have a favorable response to chemotherapy for the treatment of solid tumors, resistance to treatment often develops.   view more (2006-06-09)

Study shows chemotherapy improves survival among older breast cancer patients
The average age of a woman diagnosed with breast cancer is 63, so it is critical to have effective proven, therapies for an older patient population.   view more (2009-05-14)

Tablet is better all round for cancer patients
A drug to treat colon cancer is proving much more convenient than traditional chemotherapy, has fewer side effects - and a study of almost 2,000 patients has shown it is giving them a better chance of surviving the disease.   view more (2007-10-09)

Clear guidelines on oral chemotherapy needed
Current practices around the use of oral chemotherapy in US cancer centres need to be improved, say doctors in a study on bmj.com.   view more (2007-01-12)

UAB Study Shows Drug May Fight Biliary Cancers
Laboratory studies by University of Alabama at Birmingham (UAB) researchers have shown that the drug triphendiol (NV-196) causes cell death in pancreatic and bile duct cancer cell lines, slows tumor growth and sensitizes tumors to chemotherapy treatments.   view more (2008-04-16)

Home chemotherapy is a viable alternative to hospital treatment
Home chemotherapy is a safe and acceptable alternative to hospital treatment for patients with colorectal cancer that may improve compliance with treatment, according to a study in this week's BMJ. Of 87 patients receiving chemotherapy for colorectal cancer, 42 were treated at an outpatient clinic and 45 at home, over a 12-month period. The two... view more... (2001-04-03)

Modest Survival Benefit From Chemotherapy For Patients With Glioma Brain Tumours (p 1011)
Chemotherapy in addition to radiotherapy could have a modest survival benefit for the treatment of high-grade glioma, a severe form of brain cancer, conclude authors of a study in this week's issue of THE LANCET. Malignant gliomas are among the most devastating of cancers. They frequently result in profound and progressive disability, which often... view more... (2002-03-20)

Chemotherapy appears to delay cancer recurrence following surgery for pancreatic cancer
Use of the drug gemcitabine for chemotherapy significantly delays the recurrence of cancer, compared to no chemotherapy, for patients following pancreatic cancer surgery.   view more (2007-01-17)

First antisense drug provides benefit to subset of chronic lymphocytic leukemia patients
The first "antisense" drug to be tested in chronic lymphocytic leukemia (CLL) shows benefit in a phase III clinical trial for a specific subset of patients-those who are still sensitive to a chemotherapy drug often used to treat this cancer.   view more (2007-02-15)

Novel mechanism of taxane resistance
Research Associate Chih-Jian Lih and others working in the laboratory of Dr. Stanley N. Cohen at Stanford University have pinpointed a gene that affects human cancer cells' sensitivity to chemotherapy-an important finding in the effort to increase the effectiveness of chemotherapy.   view more (2006-07-17)

Inhibiting cell process may give cancer drug a boost
A molecule that interferes with the internal scaffolding that shapes the cell may kill cancer cells, retard the growth of tumors and give a boost to a common chemotherapy drug.   view more (2006-05-04)

Gene Test Could Reduce Unnecessary Treatment For Women With Breast Cancer (pp 340, 362)
In this week's issue of THE LANCET, US researchers describe how gene expression profiles could determine whether or not women with breast cancer would respond to docetaxel treatment. Women who are likely to be resistant to the drug could be given alternative treatment. Chemotherapy or hormonal treatment after surgery for breast cancer is crucial... view more... (2003-07-30)

New treatment shows promise against recurrent gynecologic cancers
Recurrent and metastatic endometrial and ovarian cancers can be notoriously difficult to treat: They have spread to other organs and typically have developed resistance to chemotherapy; and patients already heavily treated with chemotherapy may not be able to endure more chemo.   view more (2009-04-22)

Low-dose chemotherapy plus antiangiogenesis drug has activity in advanced breast cancer
Chemotherapy given in low, frequent doses - a novel strategy called "metronomic" delivery - achieved partial shrinkage of disease in some advanced breast cancer patients when given concurrently with an angiogenesis inhibitor.   view more (2005-12-09)

Older and poorer bowel cancer patients not given chemotherapy
Data were analysed from almost 8,000 bowel cancer patients under the age of 75, who were admitted to one of 59 hospitals in Scotland between 1990 and 1994. The results showed that 8 per cent of patients were given chemotherapy.   view more (1999-11-15)

Less-toxic drug prolongs survival in metastatic breast cancer
Research from the Northwestern University Feinberg School of Medicine has found that a less toxic, solvent-free chemotherapy drug more effectively prevents the progression of metastatic breast cancer and has fewer side effects than a commonly used solvent-based drug.   view more (2009-05-27)

Survey reveals need for standardized oral chemotherapy prescribing practices, safeguards
Despite the widespread use of prescribing safeguards for infusion chemotherapy, few of those measures have been implemented with oral chemotherapy, according to a study led by researchers at Dana-Farber Cancer Institute.   view more (2007-01-12)

New device could cut chemotherapy deaths
A new method of delivering chemotherapy to cancer patients without incurring side effects such as hair loss and vomiting is being developed.   view more (2006-03-31)
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