Childhood Leukemia Current Events | Childhood Leukemia News
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New Drug for Children with High-Risk Leukemia
Each year, approximately 4,500 children in America are diagnosed with leukemia, according to the Leukemia and Lymphoma Society. A potentially deadly cancer of the blood, it is the most common cancer in children. view more (2009-07-29)
Survivors of childhood leukemia, brain tumors more at risk for strokes later in life
Children who are successfully treated for brain tumors or leukemia are more likely to have strokes later in life, according to new research from UT Southwestern Medical Center. view more (2006-11-20)
Unique role for blood formation gene identified
All blood cell production in adults depends on the steady work of a vital gene that if lost results in early bone marrow failure, Dartmouth Medical School cancer geneticists have found. view more (2007-09-13)
The genetics of MLL leukemogenesis
In the November 1st issue of G&D, Dr. Michael Cleary (Stanford University School of Medicine) and colleagues identify the gene Meis1 as a critical player in the establishment of leukemia stem cells, and the development of MLL leukemia. view more (2007-10-17)
Scientists link genetic glitches to common childhood cancer
A multicenter team of childhood cancer researchers has discovered two genetic variations linked to an increased risk for acute lymphoblastic leukemia, or ALL, the most common childhood cancer in the United States. view more (2009-08-18)
Experimental agents may prevent radiation-induced leukemia
Treatment with biphosphonates could prevent radiation-induced leukemia, according to data presented at the American Association for Cancer Research 100th Annual Meeting 2009. view more (2009-04-20)
Gene therapy protocol at UCSD activates immune system in patients with leukemia
A research team at the Moores Cancer Center at University of California, San Diego (UCSD) reports that patients with chronic lymphocytic leukemia (CLL) who were treated with a gene therapy protocol began making antibodies that reacted against their own leukemia cells. view more (2008-02-12)
MGH study identifies first molecular steps to childhood leukemia
A Massachusetts General Hospital (MGH)-based research team has identified how a chromosomal abnormality known to be associated with acute lymphoblastic leukemia (ALL) - the most common cancer in children - initiates the disease process. view more (2009-07-16)
Steroids and chicken pox not a good mix
Children who have been treated with steroids and are exposed to chicken pox tend to have a more severe case of the virus. view more (2005-10-19)
Developing cancer treatments directed at critical developmental pathway
Researchers from the University of Pennsylvania School of Medicine and colleagues discovered that the Notch signaling pathway, which determines the development of many cell types, and is also implicated in some cancers, is not universally essential for the maintenance of stem cells. view more (2008-04-11)
UC Davis researchers shed new light on how chemotherapy-induced leukemia develops
Topoisomerase II inhibitors are among the most successful chemotherapy drugs used to treat human cancer. view more (2005-11-16)
Rate of secondary cancers increases over years after treatment for childhood leukemia
Survivors of acute lymphoblastic leukemia have a significantly increased risk of secondary cancers developing over 30 years after leukemia treatment when compared to the general population. view more (2007-03-21)
Comprehensive look at rare leukemia finds relatively few genetic changes launch disease
The most comprehensive analysis yet of the genome of childhood acute myeloid leukemia (AML) found only a few mistakes in the genetic blueprint, suggesting the cancer arises from just a handful of missteps. view more (2009-07-28)
Inherited risk factors increase odds of developing childhood acute lymphoblastic leukemia
Scientists at St. Jude Children's Research Hospital have identified inherited variations in two genes that account for 37 percent of childhood acute lymphoblastic leukemia (ALL), including a gene that may help predict drug response. view more (2009-08-17)
Lymphocyte count found to be a predictor of survival for young patients with leukemia
One simple blood test could predict relapse or survival for children and young adults with acute leukemias. view more (2007-05-08)
Childhood cancer survivors treated with radiation face increased risk of tumors later in life
University of Minnesota cancer researchers found that children who received radiation treatment for cancer face an increased risk for brain and spinal column tumors later in life. view more (2006-11-02)
Shilatifard and colleagues identify a potential target for treatment of mixed lineage leukemia
Ali Shilatifard, Ph.D., Investigator, has identified a cellular factor that can reverse histone trimethylation caused by the trithorax gene, the Drosophila homologue of the human mixed lineage leukemia gene, MLL. MLL, which is found in translocations in a variety of hematological malignancies, is a histone H3K4 methyltransferase. view more (2007-03-12)
Aggressive treatment of childhood eczema could help prevent asthma, says new study
The study, published online in the Journal of Allergy and Clinical Immunology, calls for trials of aggressive therapies against childhood eczema in attempt to reduce the incidence of asthma in later life. view more (2008-07-07)
St. Jude gene study reveals basis of anticancer drug resistance in childhood leukemia
The first analysis of the genetic determinants of resistance to the anti-cancer drug methotrexate in childhood acute lymphoblastic leukemia (ALL) could offer a pathway to predicting such resistance and treatments to overcome it, according to a St. Jude Children's Research Hospital study. view more (2008-04-16)
Dual functions of gene revealed, for better and for worse
Researchers at WEHI have pinpointed the function of a potent cancer gene. The gene, known as "ERG", has long been associated with a range of human malignancies, including leukemia and sarcoma. American scientists showed in 2005 that ERG is mutated in more than half of all prostate cancers. view more (2008-05-27)
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