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Chimeric Antigen Receptor Current Events | Chimeric Antigen Receptor News

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T vs. B: Re-engineered human T cells effectively target and kill cancerous B cells
Human white blood cells, engineered to recognize other malignant immune cells, could provide a novel therapy for patients with highly lethal B cell cancers such as acute lymphoblastic leukemia (ALL), according to researchers at Memorial Sloan-Kettering Cancer Center (MSKCC).   view more (2007-09-18)

Crucial Factors in Lymphoma Development and Survival Discovered
Researchers at National Jewish Medical and Research Center have discovered an important factor in the development of B-cell lymphomas, one of the fastest growing forms of cancer.   view more (2008-06-24)

Cell surface receptors are all 'talk' in T cell stimulation
Understanding the mechanisms that drive healthy immune responses is important when it comes to combating autoimmune diseases, which occur when cells that should attack invading organisms turn on the body instead.   view more (2008-06-13)

Rotavirus can spread beyond the intestine
A new study in PLoS Medicine has shown that children who have rotavirus, a very common cause of diarrhea in children, and who have antigens (protein fragments from the surface of the virus) in their blood, also have infectious virus in their blood.   view more (2007-04-17)

"Combination" Lyme Disease Vaccine Proteins Patented
Scientists at the U.S. Department of Energy's Brookhaven National Laboratory and collaborators at Stony Brook University have received U.S. Patent Number 7,179,448 for developing chimeric, or "combination," proteins that may advance the development of vaccines and diagnostic tests for... view more (2007-04-10)

Gene therapy protocol at UCSD activates immune system in patients with leukemia
A research team at the Moores Cancer Center at University of California, San Diego (UCSD) reports that patients with chronic lymphocytic leukemia (CLL) who were treated with a gene therapy protocol began making antibodies that reacted against their own leukemia cells.   view more (2008-02-12)

Prostate specific antigen: A review of PSA use in screening for prostate cancer
Screening for prostate cancer using prostate specific antigen (PSA) testing continues to be problematic. Even though it is unproven whether population-wide screening with PSA can reduce death, illness or disability from prostate cancer, testing has become common in North America.   view more (2007-06-19)

Annual prostate cancer screening test appears to save lives
Men who have a yearly blood test to examine their prostate specific antigen levels are nearly three times less likely to die from prostate cancer than those who don't have annual screenings.   view more (2005-10-20)

Scripps research scientists develop innovative dual action anthrax vaccine-antitoxin combination
The immune response generated in rats by the new agent protects against lethal toxin exposure after only one injection, and is faster and stronger than any currently available vaccine.   view more (2007-10-05)

Antibodies can halve risk of transplant rejection
Giving interleukin-2 receptor antibodies to patients after a kidney transplant can halve the risk of rejection, concludes a study in this week's BMJ. Researchers in Birmingham reviewed eight trials of interleukin-2 receptor antibodies versus placebo in 1,858 patients receiving standard... view more (2003-04-10)

Inhaled asthma drugs more effective than oral therapy
Inhaled glucocorticoid drugs are more effective than the newer anti-leukotriene tablets for adults with mild or moderate asthma, concludes a study in this week’s BMJ.   view more (2003-03-19)

Scientists use gene therapy to improve memory and learning in animals
Stanford University neuroscientists have designed a gene that enhances memory and learning ability in animals under stress.   view more (2006-11-08)

A Novel Strategy for Combating Aids-Related Fungal Infections
Research at the Sir William Dunn School of Pathology has identified Dectin-1 as the beta-glucan receptor on immune cells. This finding may be of use in the prophylactic prevention of a variety of infections, especially in surgical patients, and in the treatment of cancer. The identification of... view more (2004-10-08)

Sugar identified as key to malaria parasite invasion
Researchers at the Johns Hopkins Malaria Research Institute (JHMRI) have identified a sugar in mosquitoes that allows the malaria-causing parasite, Plasmodium falciparum, to attach itself to the mosquito's gut.   view more (2007-09-11)

Histochemistry is the golden standard in the diagnosis of carcinosarcomas
A case study of carcinosarcoma has been published in the World Journal of Gastroenterology on November 7, 2007. The patient in the study was the first case of gastric carcinosarcoma obtained in this part of the world.   view more (2007-11-15)

Stoned sea-squirts
The psychoactive ingredient of the drug cannabis exerts its effects on the human brain by activating proteins known as cannabinoid receptors. Dr. Maurice Elphick of Queen Mary, University of London has uncovered the first evidence that cannabinoid receptors may not be unique to humans and other... view more (2004-03-31)

Researchers identify taste receptor responsible for caffeine detection
By studying how taste-receptor mutations impact fruit fly behavior, researchers have identified a taste receptor responsible for the detection of caffeine, a bitter compound known to activate certain taste-receptor neurons, as well as impact various aspects of physiology.   view more (2006-09-19)

New hope for regenerative medicine
In the February 15th issue of G&D, Dr. K. John McLaughlin and colleagues report on their success in using uniparental embryonic stem cells to replace blood stem cells in mice.   view more (2007-02-15)

Vaccinate infants of hepatitis B mothers, say experts
Immunising newborn infants of mothers with hepatitis B prevents infection being transmitted from mother to child, finds a study published online by the BMJ today.   view more (2006-01-27)

Serum carcinoembryonic antigen level can reflect adrenal adenoma
The female patient, reported on the December 7 issue 45 of World J Gastroenterology, presented a rare case, with symptoms consistent with hyperadrenocorticism and hypercatecholaminism, and also had a Cushingoid appearance.   view more (2007-11-26)

A novel model to pinpoint human androgen receptor targets developed
A novel computational model to pinpoint androgen receptor targets within the human genome was recently reported.   view more (2005-11-01)

Arbor Vita rapid H5N1 flu diagnostic presented at ICEID meeting
Preliminary research from the Department of Respiratory Disease Research at the Naval Health Research Center (NHRC) suggests that a rapid antigen assay test developed by Arbor Vita Corporation (AVC) shows promise as a useful diagnostic for the detection of the avian influenza virus in humans.... view more (2008-03-28)

A protein sequence associated with Huntington's disease may become life-saving vaccine component
On June 10, 2008 the scientific journal "Vaccine" published a paper by the Massachusetts based biotech company Cure Lab, Inc., demonstrating that a protein sequence important in neurodegenerative Huntington's disease can be safely used as a new generation of vaccine adjuvants.   view more (2008-06-11)

UCSD researchers discover inflammation, not obesity, cause of insulin resistance
Researchers at the University of California, San Diego (UCSD) School of Medicine have discovered that inflammation provoked by immune cells called macrophages leads to insulin resistance and Type 2 diabetes.   view more (2007-11-07)

Breathe deep: Which patients could benefit from inhaled steroids in cystic fibrosis?
A specific variation in the glucocorticoid receptor gene is associated with lung disease progression in cystic fibrosis, research published this week in the online open access journal Respiratory Research reveals.   view more (2007-11-29)
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