Chromatin Current Events | Chromatin News | 3
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When every photon counts The eyes of nocturnal mammals have very large numbers of highly-sensitive rod photoreceptors (the cell type responsible for night vision). They have to perceive light which is less than a millionth of the intensity of daylight. view more (2009-04-17)
Protein plays unexpected role protecting chromosome tips A protein specialist that opens the genomic door for DNA repair and gene expression also turns out to be a multi-tasking workhorse that protects the tips of chromosomes and dabbles in a protein-destruction complex, a team lead by researchers at The University of Texas M. D. Anderson Cancer Center reports in the Aug. 13 edition of Molecular Cell. view more (2009-08-14)
How to enhance non-thermal effects of ultrasound In recent years HIFU has been widely used for the treatment of solid tumors, such as liver tumor, bone tumor, and breast cancer. The mechanism for therapeutic actions of HIFU includes thermal effects and non-thermal effects with the latter dominated by cavitational effects. view more (2008-12-29)
Scripps Research Scientists Shed Light on How DNA Is Unwound So That Its Code Can Be Read Researchers at The Scripps Research Institute have figured out how a macromolecular machine is able to unwind the long and twisted tangles of DNA within a cell's nucleus so that genetic information can be "read" and used to direct the synthesis of proteins, which have many specific functions in the body. view more (2008-11-25)
EU research suggests that PCBs damage sperm - but finds no dramatic effect on male fertility Research by an EU-supported international team of scientists has shown that polychlorinated biphenyls (PCBs)[1]-synthetic organic chemicals found widely in the environment and absorbed in the diet - may damage sperm. view more (2005-10-13)
Researchers uncover new mechanism of tumor suppressor Researchers from the University of Colorado-Denver and Health Sciences Center and Stanford University have discovered a molecular mechanism that explains how cells respond to DNA damage and other acute stresses, and if disrupted can cause cancer. view more (2006-05-22)
Genome communication In the late 19th century Gregor Mendel used peas to show that one copy of a gene (allele) is inherited from the mother and one from the father. view more (2008-06-30)
The meiotic histone code Dr. Terry Orr-Weaver and colleagues (MIT & Nagasaki University School of Medicine) present the first genetic analysis of the recently identified nucleosomal histone kinase, NHK-1. view more (2005-10-17)
Finding a cure for cancer: the holy grail of science To find a cure for cancer, the modern-day plague of our society - is synonymous to finding the holy grail of science. view more (2006-11-22)
UT Southwestern researchers find alterations in brain's circuitry caused by cocaine Cocaine causes specific alterations in the brain's circuitry at a genetic level, including short-term changes that result in a high from the cocaine, as well as long-term changes seen in addiction. view more (2005-10-24)
Enhanced environment restores memory in mice with neurodegeneration Mice whose brains had lost a large number of neurons due to neurodegeneration regained long-term memories and the ability to learn after their surroundings were enriched with toys and other sensory stimuli. view more (2007-04-30)
St. Jude study yields secrets of chromosome movement Investigators at St. Jude Children's Research Hospital have used the lowly yeast to gain insights into how a dividing human cell ensures that an identical set of chromosomes gets passed on to each new daughter cell. view more (2007-06-18)
Regulating the Nuclear Architecture of the Cell An organelle called the nucleolus resides deep within the cell nucleus and performs one of the cell's most critical functions: it manufactures ribosomes, the molecular machines that convert the genetic information carried by messenger RNA into proteins that do the work of life. view more (2006-12-11)
Targeting the dosage compensation complex Three independent research papers in the April 1 issue of G&D detail the chromosome-wide binding of the Drosophila dosage compensation complex (DCC) to the single male X chromosome, shedding new light on the mechanism of DCC targeting. view more (2006-03-17)
CSHL researchers map changing epigenetic modifications that enable transposons to run amok Much like cancer cells, plant cells grown for a long time outside of their normal milieu, in culture dishes, have highly unstable genomes. view more (2008-12-11)
Mechanism for regulation of growth and differentiation of adult muscle stem cells is revealed During muscle regeneration, which is a natural response to injury and disease, environmental cues cause adult muscle stem cells (satellite cells) to shift from dormancy to actively building new muscle tissue. view more (2007-12-10)
Getting down to cancer basics Researchers have identified a new cancer gene - one that is common to many cancers and affects the most basic regulation of our genes. The new example - a gene on the X chromosome called UTX - is found in 10% of cases of multiple myeloma and 8% of esophageal cancers. view more (2009-03-30)
Scientists uncover new class of non-protein coding genes in mammals with key functions A research team at the Broad Institute of Harvard and MIT and Beth Israel Deaconess Medical Center has uncovered a vast new class of previously unrecognized mammalian genes that do not encode proteins, but instead function as long RNA molecules. view more (2009-02-02)
Scientific evidence of the significant anti-cancer effect of milk thistle Recently, scientists demonstrated the anti-cancer effects of silibinin, a major biologically active compound of milk thistle. Being widely used as a folk remedy for liver diseases, milk thistle is safe and well-tolerated, and it protects the liver from drug or alcohol-related injury. view more (2007-11-15)
Protein binds whenever it can Dutch cancer researcher Joost Martens has discovered that the protein p300, which plays an important role in the correct transcription of DNA to RNA, can bind to DNA at several sites. The protein can also occupy a position in various complexes, each with its own protein composition. This knowledge is important for gaining a better understanding of... view more... (2003-06-24)
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