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Chromosome Current Events | Chromosome News

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Targeting the dosage compensation complex
Three independent research papers in the April 1 issue of G&D detail the chromosome-wide binding of the Drosophila dosage compensation complex (DCC) to the single male X chromosome, shedding new light on the mechanism of DCC targeting.   view more (2006-03-17)

Double identities lie behind chromosome disorders
Chromosome disorders in sex cells cause infertility, miscarriage and irregular numbers of chromosomes (aneuploidy) in neonates. A new study from Karolinska Institutet published in the scientific journal Nature Genetics shows how chromosome disorders can arise when sex cells are formed.   view more (2007-07-09)

Mouse to man: The story of chromosomes
The complete sequencing of human chromosome 17 and mouse chromosome 11 offers unique insights into the evolution of the genome of higher mammals.   view more (2006-04-20)

Essential genes cluster clue to order in the genome
The identification of a cluster of essential genes on mouse chromosome 11 as well as similar clusters on the chromosomes of other organisms - including humans - buttresses the argument that there may be rules as to how genes are structured or laid out on chromosomes.   view more (2007-05-04)

Protein 'chatter' linked to cancer activation
Scientists have found the existence of cross-talk between human chromosome ends and the protein complexes central to the stability of the entire human genome, a "chat" that contributes to cancer development.   view more (2007-08-14)

Mapping the genetic locus for triglycerides
Researchers have mapped out a region on human chromosome 1 that contributes to genetically elevated blood triglyceride levels, a major risk factor for heart disease.   view more (2008-04-28)

RNAi and telomere length
A team of Russian scientists, led by Dr. Vladimir Gvozdev (Russian Academy of Sciences) reports on a novel link between RNAi and telomere maintenance in the Drosophila germline.   view more (2006-02-01)

DNA could reveal your surname
Scientists at the world-leading Department of Genetics at the University of Leicester - where the revolutionary technique of genetic fingerprinting was invented by Professor Sir Alec Jeffreys- are developing techniques which may one day allow police to work out someone's surname from the DNA alone.   view more (2008-10-08)

X-Effect: Female Chromosome Confirmed a Prime Driver of Speciation
Researchers at the University of Rochester believe they have just confirmed a controversial theory of evolution. The X chromosome is a strikingly powerful force in the origin of new species.   view more (2007-10-18)

Susceptibility To Psychotic Illness In Prader Willi Syndrome Linked To Gene On Chromosome 15 (p 135)
Authors of a research letter in this week's issue of THE LANCET-which investigated the occurrence of severe psychotic illness in adults with Prader Willi syndrome-suggest that susceptibility to psychotic illness in the general population could be influenced by genetic abnormalities on chromosome 15.   view more (2002-01-11)

A new explanation for evolutionary changes in genetic sex-determination systems
In animals with separate sexes, embryos commit to becoming male or female at an early stage. Often this key decision is made by sex determination genes on the sex chromosomes. The genes involved in sexual development have changed remarkably little during evolution. In contrast, the sex... view more (2007-10-22)

GENETIC EVIDENCE FOR LINK BETWEEN COSMIC RADIATION AND LEUKAEMIA IN AIRCREW (p 2158)
The association between exposure to cosmic radiation and leukaemia among aircrew is strengthened by genetic research published in this week's issue of THE LANCET. Previous research by Maryanne Gundestrup and colleagues from the Institute of Cancer Epidemiology, Copenhagen, Denmark... view more (2000-12-21)

Non-coding RNAs help silence the mammalian transcription
Dr. Shirley Tilghman and colleagues (Princeton University) lend new insight into the mechanism of genomic imprinting, demonstrating a necessary role for a non-coding RNA transcript in the silencing of an imprinted gene cluster in mice.   view more (2006-05-15)

Physicist cracks women's random but always lucky choice of X chromosome
A University of Warwick physicist has uncovered how female cells are able to choose randomly between their two X chromosomes and why that choice is always lucky.   view more (2007-06-13)

OHSU Cancer Institute research discovery opens new window to understanding chronic myeloid leukemia
Oregon Health & Science University Cancer Institute researchers have opened a new window into the roots of chronic myeloid leukemia (CML).   view more (2007-12-10)

Geneticists Determine The Lack Of Chromosomes
A healthy person's genome contains 46 chromosomes, but an individual cell can contain less. Contemporary methods allow to determine the value of losses rather accurately. The Tomsk researchers' effort has been supported by the Russian Foundation for Basic Research. An average statistical cell of a... view more (2004-06-15)

"Acquittal" for Suspected Schizophrenia Gene
Just under one per cent of all Germans suffer from schizophrenia. The susceptibility to contracting this severe psychological disease is inherited; various studies indicate that a gene on chromosome 1 shares responsibility for the outbreak of the disease. However, in what is the biggest control... view more (2002-04-22)

Researchers shed light on shrinking of chromosomes
A human cell contains an enormous 1.8 metres of DNA partitioned into 46 chromosomes.   view more (2007-06-12)

First gene associated with myeloproliferative diseases
Myelodysplastic / myeloproliferative diseases (MDS/MPD) are blood stem cell disorders characterized by ineffective formation and development of blood cells in the bone marrow, resulting in abnormal development of bone marrow precursor cells and a reduction in the number of blood cells.   view more (2005-08-26)

Scientists take a step nearer to creating an artificial egg using a somatic cell
Scientists believe that they are an important step nearer to success in creating an artificial egg from the combination of the nucleus of a somatic cell and an oocyte which has had its DNA-carrying nucleus removed, a conference of international fertility experts heard today (Tuesday 1 July). Dr... view more (2003-06-28)

Zeroing in on Alzheimer's
Hereditary Alzheimer's disease has been shown to be the result of mutations in certain specific genes. Other cases of Alzheimer's are also assumed to be traceable to the influence of a number of still unidentified genes. It is probable that these genes are located in a large area on chromosome 10q,... view more (2003-09-25)

Rong Li Lab probes mechanism of asymmetry in meiotic cell division
The Stowers Institute's Rong Li Lab has characterized a mechanism that allows for asymmetrical cell division during meiosis in oocytes. By tracking chromosome movement in live mouse oocytes, the team discovered that chromosomes can recruit to their vicinity a protein called formin-2.   view more (2008-10-08)

Duke-NIEHS team shows how DNA repairs may reshape the genome
Researchers at Duke University Medical Center and at the National Institute of Environmental Health Sciences (NIEHS) have shown how broken sections of chromosomes can recombine to change genomes and spawn new species.   view more (2008-08-14)

Embryonic selection of sex avoids conceiving blind children
The Assisted Reproduction Unit at the Quirón Hospital in Donostia-San Sebastián has managed, for the first time in the Basque Country, to successfully carry out an embryonic sex selection in a woman who is a carrier of the disease Retinosis Pigmentaria, linked with the X chromosome - in order to... view more (2006-12-19)

Evolution of genomic imprinting
How we come to express the genes of one parent over the other is now better understood through studying the platypus and marsupial wallaby - and it doesn't seem to have originated in association with sex chromosomes.   view more (2007-09-07)
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