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Chromosome Current Events | Chromosome News
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Targeting the dosage compensation complex
Three independent research papers in the April 1 issue of G&D detail the chromosome-wide binding of the Drosophila dosage compensation complex (DCC) to the single male X chromosome, shedding new light on the mechanism of DCC targeting. view more (2006-03-17)
Double identities lie behind chromosome disorders
Chromosome disorders in sex cells cause infertility, miscarriage and irregular numbers of chromosomes (aneuploidy) in neonates. A new study from Karolinska Institutet published in the scientific journal Nature Genetics shows how chromosome disorders can arise when sex cells are formed. view more (2007-07-09)
Baumann Lab demonstrates role of protein in distinguishing chromosome ends from DNA breaks
The Stowers Institute's Baumann Lab has demonstrated how human cells protect chromosome ends from misguided repairs that can lead to cancer. view more (2009-09-18)
Mouse to man: The story of chromosomes
The complete sequencing of human chromosome 17 and mouse chromosome 11 offers unique insights into the evolution of the genome of higher mammals. view more (2006-04-20)
Essential genes cluster clue to order in the genome
The identification of a cluster of essential genes on mouse chromosome 11 as well as similar clusters on the chromosomes of other organisms - including humans - buttresses the argument that there may be rules as to how genes are structured or laid out on chromosomes. view more (2007-05-04)
Newly-discovered mechanism can explain the Beckwith-Wiedemann syndrome
Researchers from Uppsala University have discovered a mechanism that silences several genes in a chromosome domain. The findings, published in today's on-line issue of Molecular Cell, have implications in understanding the human disorder Beckwith-Wiedemann syndrome. view more (2008-10-27)
Protein 'chatter' linked to cancer activation
Scientists have found the existence of cross-talk between human chromosome ends and the protein complexes central to the stability of the entire human genome, a "chat" that contributes to cancer development. view more (2007-08-14)
Mapping the genetic locus for triglycerides
Researchers have mapped out a region on human chromosome 1 that contributes to genetically elevated blood triglyceride levels, a major risk factor for heart disease. view more (2008-04-28)
RNAi and telomere length
A team of Russian scientists, led by Dr. Vladimir Gvozdev (Russian Academy of Sciences) reports on a novel link between RNAi and telomere maintenance in the Drosophila germline. view more (2006-02-01)
DNA could reveal your surname
Scientists at the world-leading Department of Genetics at the University of Leicester - where the revolutionary technique of genetic fingerprinting was invented by Professor Sir Alec Jeffreys- are developing techniques which may one day allow police to work out someone's surname from the DNA alone. view more (2008-10-08)
X-Effect: Female Chromosome Confirmed a Prime Driver of Speciation
Researchers at the University of Rochester believe they have just confirmed a controversial theory of evolution. The X chromosome is a strikingly powerful force in the origin of new species. view more (2007-10-18)
Susceptibility To Psychotic Illness In Prader Willi Syndrome Linked To Gene On Chromosome 15 (p 135)
Authors of a research letter in this week's issue of THE LANCET-which investigated the occurrence of severe psychotic illness in adults with Prader Willi syndrome-suggest that susceptibility to psychotic illness in the general population could be influenced by genetic abnormalities on chromosome 15. view more (2002-01-11)
A new explanation for evolutionary changes in genetic sex-determination systems
In animals with separate sexes, embryos commit to becoming male or female at an early stage. Often this key decision is made by sex determination genes on the sex chromosomes. The genes involved in sexual development have changed remarkably little during evolution. In contrast, the sex determination genes and the sex chromosomes themselves are... view more... (2007-10-22)
GENETIC EVIDENCE FOR LINK BETWEEN COSMIC RADIATION AND LEUKAEMIA IN AIRCREW (p 2158)
The association between exposure to cosmic radiation and leukaemia among aircrew is strengthened by genetic research published in this week's issue of THE LANCET. Previous research by Maryanne Gundestrup and colleagues from the Institute of Cancer Epidemiology, Copenhagen, Denmark (Radiation-induced acute myeloid leukaemia and other cancers in... view more... (2000-12-21)
Non-coding RNAs help silence the mammalian transcription
Dr. Shirley Tilghman and colleagues (Princeton University) lend new insight into the mechanism of genomic imprinting, demonstrating a necessary role for a non-coding RNA transcript in the silencing of an imprinted gene cluster in mice. view more (2006-05-15)
Sex talk revelations of the lonely Y chromosome
In the week that the University of Leicester celebrates the 25th anniversary of the discovery of DNA fingerprinting new findings from the world-renowned University of Leicester Department of Genetics reveal for the first time that the male and female do truly communicate -at least at the fundamental genetic level. view more (2009-09-11)
Physicist cracks women's random but always lucky choice of X chromosome
A University of Warwick physicist has uncovered how female cells are able to choose randomly between their two X chromosomes and why that choice is always lucky. view more (2007-06-13)
OHSU Cancer Institute research discovery opens new window to understanding chronic myeloid leukemia
Oregon Health & Science University Cancer Institute researchers have opened a new window into the roots of chronic myeloid leukemia (CML). view more (2007-12-10)
Geneticists Determine The Lack Of Chromosomes
A healthy person's genome contains 46 chromosomes, but an individual cell can contain less. Contemporary methods allow to determine the value of losses rather accurately. The Tomsk researchers' effort has been supported by the Russian Foundation for Basic Research. An average statistical cell of a healthy person contains 46 chromosomes. But a... view more... (2004-06-15)
Small RNAs can play critical roles in male infertility/contraception
University of Nevada School of Medicine scientists in the Department of Physiology and Cell Biology have discovered insight into the reproductive workings of the male sex chromosome that may have significant implications for male infertility and contraception. view more (2009-04-10)
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