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Chromosome Current Events | Chromosome News | 11

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Suppression of FOXO1a gene might kill resistant ARMS tumors
The loss of function of a gene called FOXO1a plays an important role in the development of the most common cancer of soft tissues in children, and restoring the function of that gene in cancer cells suppresses that cancer.   view more (2005-09-22)

New, less invasive genetic test greatly improves pregnancy rates in older women with poor prognosis
A new test examining chromosomes in human eggs a few hours after fertilisation can identify those that are capable of forming a healthy baby.   view more (2009-06-30)

Advances in the characterisation of the oyster mushroom genes
The oyster mushroom (Pleurotus ostreatus), apart from reducing cholesterol and having anticancerogenic properties, is characterised for its capacity for breaking down cellulose. Finding out which genes are responsible for this activity - the reason why the fungus is sometimes used as a decontaminating agent, was the aim of the PhD thesis by... view more... (2005-03-15)

Male infertility: Scientists discover candidate gene for impaired spermatogenesis
Lausanne, Switzerland: Researchers in the Netherlands believe they have identified a gene that is involved in causing infertility in men. Dr Judith Gianotten told the European Society of Human Reproduction and Embryology annual meeting in Lausanne today (Wednesday 4 July) that the ZNF214 gene is probably a candidate gene for impaired... view more... (2001-07-03)

Chromosomal abnormalities in sperm higher after vasectomy reversal
Men who have had a vasectomy reversed have a very much greater rate of chromosomal abnormalities in their sperm than do normal fertile men.   view more (2006-06-21)

Chlamydia that avoids diagnosis
New sequencing and analysis of six strains Chlamydia will result in improved diagnosis of the sexually transmitted infection.   view more (2009-05-21)

Test can predict spread of eye cancer to liver
Scientists at Washington University School of Medicine in St. Louis have developed a method to predict whether melanoma of the eye will spread to the liver, where it quickly turns deadly.   view more (2006-09-14)

Gene's discovery could help prevent a leading cause of blindness in the elderly
University of Pittsburgh researchers have discovered a gene linked to age-related maculopathy (ARM), the leading cause of untreatable blindness in the elderly.   view more (2005-08-17)

AMN107 has potent activity in leukemia resistant to Gleevec
The targeted agent AMN107 can produce dramatic benefits in patients with some forms of leukemia that are resistant to Gleevec, the standard therapy for these cancers, say researchers at The University of Texas M. D. Anderson Cancer Center.   view more (2005-12-12)

Researchers report gene associated with language, speech and reading disorders
A new candidate gene for Specific Language Impairment has been identified by a research team directed by Mabel Rice at the University of Kansas, in collaboration with Shelley Smith, University of Nebraska Medical Center, and Javier Gayán of Neocodex, Seville, Spain.   view more (2009-08-28)

St. Jude finds factors that accelerate resistance to targeted therapy in lymphoblastic leukemia
Results of a study by investigators at St. Jude Children's Research Hospital provide strong evidence for why the targeted therapy drug imatinib (Gleevec™), which has revolutionized the treatment of chronic myelogenous leukemia (CML), is often unable to prevent relapse of a particularly aggressive form of acute lymphoblastic leukemia (ALL).   view more (2007-08-30)

Gene dose affects tumor growth
Researchers at Johns Hopkins and Ohio State University have found that the number of copies of a particular gene can affect the severity of colon cancer in a mouse model.   view more (2008-01-04)

Gene may hold key to future cancer hope
Scientists may have discovered a new way of killing tumours in what they hope could one day lead to alternative forms of cancer treatments.   view more (2007-10-09)

Case Western Reserve research finds that the lack of specific gene plays role in autism
It is estimated that three to six out of every 1,000 children in the United States have autism - and the number of diagnosed cases is rising.   view more (2009-02-09)

Sex hormone signature indicates gender rather than just chromosomes
Help with assigning gender could one day be at hand for intersex individuals whose genital phenotypes and sex chromosomes don't match, thanks to the discovery of a stable sex hormone signature in our cells.   view more (2007-10-18)

Leiden scientists sequence first female DNA
Geneticists of Leiden University Medical Centre (LUMC) are the first to determine the DNA sequence of a woman. She is also the first European whose DNA sequence has been determined. This has been announced by the researchers this morning, during a special press conference at 'Bessensap', a yearly meeting of scientists and the press in the... view more... (2008-05-28)

Researchers take first look at the genetic dynamics of inbreeding depression
Researchers have taken a first look at the broad genetic changes that accompany reproductive declines in inbred populations.   view more (2009-03-13)

Variation in 3 genes influences risk of age-related macular degeneration
Researchers in Boston have discovered a new common, noncoding variant in the Complement Factor H (CFH) gene that is associated with age-related macular degeneration (AMD), the leading cause of irreversible visual impairment and blindness among persons aged 60 and older.   view more (2006-08-30)

Novel discovery of DCDC2 gene associated with dyslexia
Pediatric researchers at Yale School of Medicine have identified a gene on human chromosome 6 called DCDC2, which is linked to dyslexia, a reading disability affecting millions of children and adults.   view more (2005-10-31)

New tumor markers determine therapy intensity
Characteristic changes in the DNA of medulloblastoma, the most frequent malignant brain tumor in childhood, indicate precisely how aggressively the tumor will continue to spread and what the chances of disease relapse are.   view more (2009-03-18)
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