Chromosome Current Events | Chromosome News | 3
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Baumann Lab Defines Proteins that Distinguish Chromosome Ends from DNA Double-Strand Breaks
Peter Baumann, Ph.D., Assistant Investigator, and Nancy Bae, Ph.D., Postdoctoral Research Associate in the Baumann Lab, have published a paper offering insight into the way cells protect chromosome ends from misguided repair. view more (2007-05-11)
Chromosome regions containing genes related to alcohol addiction affect drinking behavior in smokers
Scientists have found in a study of tobacco users that their drinking behavior is linked to some of the same chromosome regions associated with alcohol addiction. view more (2005-12-22)
Movement of chromosome in nucleus visualized
The cell is understood to be highly organized, with specialized areas for different functions and molecular motors shuttling components around. view more (2006-04-18)
Workman Lab characterizes novel regulator of chromosome function
The Stowers Institute's Workman Lab has shed new light on a novel histone acetyltransferase protein complex called ATAC. Acetyltransferases are enzymes that introduce a new acetyl functional group into histone proteins, a process by which all chromosome functions are controlled. view more (2008-03-11)
LSUHSC research helps link schizophrenia to specific DNA region
For the first time, an international group of researchers has found genetic evidence linking schizophrenia to a specific region of DNA - on chromosome 6. view more (2009-07-09)
Centromeres cross over, a lot
Recombination at centromeres is higher than anywhere else on the chromosome, even though methyltransferases do their best to prevent it, say Jaco et al., as published in the June 16 issue of the Journal of Cell Biology. view more (2008-06-13)
Different but equal: Settling the dosage compensation debate
Independent research papers from Dr. Peter Becker (Munich, Germany) and Dr. Mitzi Kuroda (Boston, MA) in the October 1 issue of Genes & Development delineate the mechanism of X-chromosome dosage compensation in Drosophila. view more (2005-10-03)
Fruit fly gene research may shed light on human disease processes
Those small fruit flies buzzing around your bananas are more than pests—they may be allies in a fruitful search for clues to human diseases caused when genes malfunction. view more (2007-03-28)
Genetic Imbalance Could Help Predict Colorectal Cancer Prognosis (pp 183, 219)
Results of a study in this week's issue of THE LANCET suggest that an imbalance in specific genetic material on chromosomes 8 and 18 could be a better predictor of colorectal cancer prognosis than conventional histopathological assessment. Chromosome imbalances occur in many cancers and represent important biological properties of tumours.... view more... (2002-01-17)
Region of DNA strongly associated with Alzheimer's disease
An international team of researchers, led by investigators at Washington University School of Medicine in St. Louis, are zeroing in on a gene that increases risk for Alzheimer's disease. view more (2006-01-11)
Susceptibility to Crohn's disease — an important new clue
Crohn's disease is a chronic relapsing inflammatory disorder of the intestinal tract that affects an estimated 0.15% of people in the developed world. view more (2007-04-23)
Normal chromosome ends elicit a limited DNA damage response
Researchers at the Salk Institute for Biological Studies discovered that cells co-opted the machinery that usually repairs broken strands of DNA to protect the integrity of chromosomes. view more (2005-11-28)
MGH Cancer Center researchers find new gene associated with Wilms tumor
Researchers at the Massachusetts General Hospital (MGH) Cancer Center have discovered a novel gene mutation associated with Wilms tumor, the most common pediatric kidney cancer. view more (2007-01-05)
Nature press release on DiGeorge syndrome paper
[410097] LIFELINES: CATCH 22 (pp97–101) In the 1 March issue of Nature, researchers from Baylor College of Medicine in Texas pinpoint the gene behind one of the most common genetic diseases to affect humans: DiGeorge syndrome. The disease results in a broad spectrum of symptoms, including heart abnormalities, disruption of the immune system... view more... (2001-02-23)
Gerton Lab determines the composition of centromeric chromatin
The Stowers Institute's Gerton Lab has provided new evidence to clarify the structure of nucleosomes containing Cse4, a centromere-specific histone protein required for proper kinetochore function, which plays a critical role in the process of mitosis. The work, conducted in yeast cells, was published in the most recent issue of Molecular Cell. view more (2009-09-29)
Chromosome glue repairs damaged DNA
When a strand of DNA breaks in the body's cells, it normally does not take long until it has been repaired. Now researchers at the Swedish medical university Karolinska Institutet have discovered a new mechanism that helps to explain how the cell performs these repairs. The results are presented in Science. view more (2007-07-16)
A balancing act between the sexes
Recent research at the European Molecular Biology Laboratory (EMBL) reveals new insights into how cells achieve equality between the sexes. view more (2006-03-17)
Female human embryos adjust the balance of X chromosomes before implantation
Dutch researchers have found the first evidence that a process of inactivating the X chromosome during embryo development and implantation, which was known to occur in mice but unknown in humans, does, in fact, take place in human female embryos prior to implantation in the womb. view more (2009-06-30)
Researchers discover baldness gene: 1 in 7 men at risk
Researchers at McGill University, King's College London and GlaxoSmithKline Inc. have identified two genetic variants in caucasians that together produce an astounding sevenfold increase the risk of male pattern baldness. view more (2008-10-13)
1 moose, 2 moose: Scientist seeks correction in number of species
It is a misinterpretation of the application of the bedrock of scientific naming with regard to the number of moose species that Kris Hundertmark, a University of Alaska Fairbanks wildlife geneticist at the Institute of Arctic Biology, seeks to correct. view more (2009-06-15)
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