Chromosome Damage Current Events | Chromosome Damage News
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Double identities lie behind chromosome disorders
Chromosome disorders in sex cells cause infertility, miscarriage and irregular numbers of chromosomes (aneuploidy) in neonates. A new study from Karolinska Institutet published in the scientific journal Nature Genetics shows how chromosome disorders can arise when sex cells are formed. view more (2007-07-09)
Targeting the dosage compensation complex
Three independent research papers in the April 1 issue of G&D detail the chromosome-wide binding of the Drosophila dosage compensation complex (DCC) to the single male X chromosome, shedding new light on the mechanism of DCC targeting. view more (2006-03-17)
Mouse to man: The story of chromosomes
The complete sequencing of human chromosome 17 and mouse chromosome 11 offers unique insights into the evolution of the genome of higher mammals. view more (2006-04-20)
UCLA cancer researchers first to link intestinal inflammation with systemic chromosome damage
UCLA scientists have linked for the first time intestinal inflammation with systemic chromosome damage in mice, a finding that may lead to the early identification and treatment of human inflammatory disorders. view more (2009-06-01)
Baumann Lab demonstrates role of protein in distinguishing chromosome ends from DNA breaks
The Stowers Institute's Baumann Lab has demonstrated how human cells protect chromosome ends from misguided repairs that can lead to cancer. view more (2009-09-18)
Evidence of rapid evolution is found at the tips of chromosomes
In terms of their telomeres, mice are more complicated than humans. That's the finding from a recent Rockefeller University study, which shows that mice have two proteins working together to do the job of a single protein in human cells. view more (2006-08-02)
Normal chromosome ends elicit a limited DNA damage response
Researchers at the Salk Institute for Biological Studies discovered that cells co-opted the machinery that usually repairs broken strands of DNA to protect the integrity of chromosomes. view more (2005-11-28)
Essential genes cluster clue to order in the genome
The identification of a cluster of essential genes on mouse chromosome 11 as well as similar clusters on the chromosomes of other organisms - including humans - buttresses the argument that there may be rules as to how genes are structured or laid out on chromosomes. view more (2007-05-04)
Newly-discovered mechanism can explain the Beckwith-Wiedemann syndrome
Researchers from Uppsala University have discovered a mechanism that silences several genes in a chromosome domain. The findings, published in today's on-line issue of Molecular Cell, have implications in understanding the human disorder Beckwith-Wiedemann syndrome. view more (2008-10-27)
Protein 'chatter' linked to cancer activation
Scientists have found the existence of cross-talk between human chromosome ends and the protein complexes central to the stability of the entire human genome, a "chat" that contributes to cancer development. view more (2007-08-14)
Mapping the genetic locus for triglycerides
Researchers have mapped out a region on human chromosome 1 that contributes to genetically elevated blood triglyceride levels, a major risk factor for heart disease. view more (2008-04-28)
RNAi and telomere length
A team of Russian scientists, led by Dr. Vladimir Gvozdev (Russian Academy of Sciences) reports on a novel link between RNAi and telomere maintenance in the Drosophila germline. view more (2006-02-01)
Researchers shed light on shrinking of chromosomes
A human cell contains an enormous 1.8 metres of DNA partitioned into 46 chromosomes. view more (2007-06-12)
Duke-NIEHS team shows how DNA repairs may reshape the genome
Researchers at Duke University Medical Center and at the National Institute of Environmental Health Sciences (NIEHS) have shown how broken sections of chromosomes can recombine to change genomes and spawn new species. view more (2008-08-14)
DNA repair mechanisms are concentrated in the active parts of the genome
Less than 10% of the human genome contains coded information in the form of genes. The 30,000-40,000 genes in the genome are found grouped in discrete regions of the chromosomes. Chemical agents and radiation habitually cause a large variety of injuries to the DNA which interferes in many cell processes, like transcription and replication, and... view more... (2002-10-01)
DNA could reveal your surname
Scientists at the world-leading Department of Genetics at the University of Leicester - where the revolutionary technique of genetic fingerprinting was invented by Professor Sir Alec Jeffreys- are developing techniques which may one day allow police to work out someone's surname from the DNA alone. view more (2008-10-08)
X-Effect: Female Chromosome Confirmed a Prime Driver of Speciation
Researchers at the University of Rochester believe they have just confirmed a controversial theory of evolution. The X chromosome is a strikingly powerful force in the origin of new species. view more (2007-10-18)
Chromosome glue repairs damaged DNA
When a strand of DNA breaks in the body's cells, it normally does not take long until it has been repaired. Now researchers at the Swedish medical university Karolinska Institutet have discovered a new mechanism that helps to explain how the cell performs these repairs. The results are presented in Science. view more (2007-07-16)
Susceptibility To Psychotic Illness In Prader Willi Syndrome Linked To Gene On Chromosome 15 (p 135)
Authors of a research letter in this week's issue of THE LANCET-which investigated the occurrence of severe psychotic illness in adults with Prader Willi syndrome-suggest that susceptibility to psychotic illness in the general population could be influenced by genetic abnormalities on chromosome 15. view more (2002-01-11)
A new explanation for evolutionary changes in genetic sex-determination systems
In animals with separate sexes, embryos commit to becoming male or female at an early stage. Often this key decision is made by sex determination genes on the sex chromosomes. The genes involved in sexual development have changed remarkably little during evolution. In contrast, the sex determination genes and the sex chromosomes themselves are... view more... (2007-10-22)
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