Chromosomes Current Events | Chromosomes News | 5
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Microtubule protein interactions visualized en masse
In a new study published online in the open access journal PLoS Biology, Philipp Niethammer, Eric Karsenti, and colleagues investigate the regulation of microtubule dynamics via application of their new method, called visual immunoprecipitation (VIP), which enables simultaneous visualization of multiple protein interactions in cell extracts. view more (2007-01-16)
When cells go bad
When a cell's chromosomes lose their ends, the cell usually kills itself to stem the genetic damage. But University of Utah biologists discovered how those cells can evade suicide and start down the path to cancer. view more (2008-10-01)
New method of testing eggs for abnormalities could solve problems of embryo freezing
Italian researchers have shown for the first time that it is possible to test a woman's egg, before fertilisation, for chromosomal abnormalities that might make an embryo less likely to implant successfully or more likely to miscarry at a later stage. view more (2006-06-19)
'Ageing gene' could be passed on via X chromosome (p 507)
An observational study in this week's issue of THE LANCET sheds more light on the theory that ageing is associated with a shortening of chromosomes in somatic (ie. non-reproductive) cells. Results of the study suggest that the gene responsible for telomere shortening is inherited via the X chromosome. Previous research including a 2003 Lancet... view more... (2004-02-11)
Research sheds light on cause of Down syndrome and other genetic disorders
Scientists have a better understanding of what causes an abnormal number of chromosomes in offspring, a condition called aneuploidy that encompasses the most common genetic disorders in humans, such as Down syndrome, and is a leading cause of pregnancy loss. view more (2009-07-20)
New, less invasive genetic test greatly improves pregnancy rates in older women with poor prognosis
A new test examining chromosomes in human eggs a few hours after fertilisation can identify those that are capable of forming a healthy baby. view more (2009-06-30)
Chromosomal microarray analysis proves accurate
Two years and more than 2,000 samples after researchers at Baylor College of Medicine started to use a new gene-chip technology called chromosomal microarray analysis to look for potential genetic abnormalities in children, they find that it is remarkably sensitive in detecting abnormalities in individual chromosomes. view more (2007-03-30)
New technique yields more detailed picture of chromatin structure
University of Illinois researchers have developed a technique for imaging cells under an electron microscope that yields a sharper image of the structure of chromatin, the tightly wound bundle of genetic material and proteins that makes up the chromosomes. view more (2008-04-17)
HIV inserts into human genome using a DNA-associated protein
A human DNA-associated protein called LEDGF is the first such molecule found to control the location of HIV integration in human cells. view more (2005-11-28)
St. Jude study yields secrets of chromosome movement
Investigators at St. Jude Children's Research Hospital have used the lowly yeast to gain insights into how a dividing human cell ensures that an identical set of chromosomes gets passed on to each new daughter cell. view more (2007-06-18)
Shortening chromosomes cause for earlier cancer onset in families with rare syndrome
In families with a high incidence of Li-Fraumeni syndrome, the ends of individuals' chromosomes act somewhat like a lit fuse, according to researchers at The Hospital for Sick Children in Toronto. view more (2007-02-16)
Med school discovery could lead to better cancer diagnosis, drugs
A Florida State University College of Medicine research team led by Yanchang Wang has discovered an important new layer of regulation in the cell division cycle, which could lead to a greater understanding of the way cancer begins. view more (2008-11-24)
In rare disease, a familiar protein disrupts gene function
An international team of scientists studying a rare genetic disease discovered that a bundle of proteins with the long-established function of keeping chromosomes together also plays an important role in regulating genes in humans. view more (2009-05-27)
The story of X -- evolution of a sex chromosome
In the first evolutionary study of the chromosome associated with being female, University of California, Berkeley, biologist Doris Bachtrog and her colleagues show that the history of the X chromosome is every bit as interesting as the much-studied, male-determining Y chromosome, and offers important clues to the origins and benefits of sexual... view more... (2009-04-17)
Chromosomal chaos in early embryonic development is linked to abnormalities in cytokinesis and spindle formation
Berlin, Germany: Abnormalities in the spindles (the bi-polar thread like structures that link and pull the chromosomes during cell division) of human embryos before implantation may be the primary reason for many of the chromosome defects observed in early human development, a scientist said on Wednesday 30 June 2004 at the 20th annual conference... view more... (2004-06-29)
Molecular Biologists Reveal Historical Secrets
By analysing DNA from ancient human remains researchers can determine the sex and ethnicity of our ancestors and help historians to compose a complete picture of their life and customs. In the region of Altai Mountains archaeologists discovered remains of an ancient civilisation. During excavations, they found many bones of newborns and wondered... view more... (2002-07-05)
Mayo Clinic study points to a possible biomarker for colon cancer in people 50 and under
An abnormality of chromosomes long associated with diseases of aging has, for the first time, been linked to colon cancer in people 50 years old and younger, an age group usually considered young for this disease. view more (2007-10-29)
Genetic conflict in fish led to evolution of new sex chromosomes
University of Maryland biologists have genetically mapped the sex chromosomes of several species of cichlid (pronounced "sick-lid") fish from Lake Malawi, East Africa, and identified a mechanism by which new sex chromosomes may evolve. view more (2009-10-02)
CSHL scientists discover link between control of chromosome duplication and segregation
Before a cell can divide into two, first it must duplicate its genetic material--the DNA packed in its chromosomes. The two new sets of chromosomes then have to be separated from one another and correctly distributed to the resulting "daughter" cells, so that both daughter cells are genetically identical to the original, or... view more... (2009-02-06)
Chromosome Assessment Could Predict Increased Risk Of Death From Age-related Disease (p 393)
US authors of a research letter in this week's issue of THE LANCET highlight how the measurement of the ends of chromosomes in older people could give an indication of their relative risks of dying from age-related diseases. The ends of chromosomes (telomeres) shorten with age, and this shortening may contribute to the increased risk of disease... view more... (2003-01-29)
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