Chronic Myeloid Leukemia Current Events | Chronic Myeloid Leukemia News | 6
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Three molecular triggers threaten leukemia patients
The road to better treatment for the most common form of adult leukemia will require blocking multiple molecular pathways that fuel the disease. view more (2006-10-04)
Researchers describe how chronic inflammation can lead to stomach cancer
A multi-center research team, led by Columbia University Medical Center, has uncovered a major contributor to the cause of stomach cancer - the second leading cause of cancer-related mortality in the world. view more (2008-11-06)
Patient with rare disorder responds to cancer drug
A rare disorder caused by an excess of two types of immune cells-the mast cell found in various tissues and its blood-based twin, the basophil-has successfully been treated with a cancer drug, report scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH). view more (2008-02-14)
First antisense drug provides benefit to subset of chronic lymphocytic leukemia patients
The first "antisense" drug to be tested in chronic lymphocytic leukemia (CLL) shows benefit in a phase III clinical trial for a specific subset of patients-those who are still sensitive to a chemotherapy drug often used to treat this cancer. view more (2007-02-15)
Developing cancer treatments directed at critical developmental pathway
Researchers from the University of Pennsylvania School of Medicine and colleagues discovered that the Notch signaling pathway, which determines the development of many cell types, and is also implicated in some cancers, is not universally essential for the maintenance of stem cells. view more (2008-04-11)
Early Phase II results show bosutinib safe, effective for CML
A new drug for chronic myelogenous leukemia works for patients who have developed resistance to frontline therapy and causes fewer side effects than other medications in its class, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports at the 49th annual meeting of the American Society of Hematology. view more (2007-12-11)
Drug could provide first treatment for scleroderma
Investigators have identified a drug that is currently approved to treat certain types of cancer, Gleevec, that could provide the first treatment for scleroderma, a chronic connective tissue disease for which a treatment has remained elusive. view more (2009-10-19)
FDA approved leukemia drugs shows promise in ovarian cancer cells
The drug Sprycel, approved for use by the U.S. Food and Drug Administration in patients with chronic myeloid leukemia, significantly inhibited the growth and invasiveness of ovarian cancer cells and also promoted their death, a study by researchers with UCLA's Jonsson Comprehensive Cancer Center found. view more (2009-11-10)
Dual role in breast tissue for a protein involved in leukemia
A protein known to play a role in growth of some types of leukemia appears to have a mixed function in breast cancer development, say researchers from the Lombardi Comprehensive Cancer Center at Georgetown University Medical Center (GUMC). view more (2009-06-15)
Mind over matter
A significant number of people world-wide suffer with chronic pain, which affects every aspect of their lives, and often results in depression. view more (2006-08-29)
St. Jude finds factors that accelerate resistance to targeted therapy in lymphoblastic leukemia
Results of a study by investigators at St. Jude Children's Research Hospital provide strong evidence for why the targeted therapy drug imatinib (Gleevec™), which has revolutionized the treatment of chronic myelogenous leukemia (CML), is often unable to prevent relapse of a particularly aggressive form of acute lymphoblastic leukemia (ALL). view more (2007-08-30)
A Broken Stress Response System Can Contribute to Gleevec Resistance
New clues to why some kinds of leukemia are more aggressive and deadly than others are coming from research examining the types of genetic damage that allow some blood cells to grow out of control, scientists report. view more (2006-04-21)
St. Jude discovery offers new avenues to understanding an aggressive form of leukemia
Researchers at St. Jude Childrenˇ¦s Research Hospital have discovered evidence that a series of genetic mutations work together to initiate most cases of an aggressive and often-fatal form of acute lymphoblastic leukemia (ALL). view more (2008-04-15)
Novel treatments show improvements in survival and response rates for leukemia and lymphoma
The use of dexamethasone early in the treatment of children with acute lymphoblastic leukemia, the most common type of childhood cancer, may help reduce the risk of relapse. view more (2008-12-08)
Acupuncture more effective than massage for chronic neck pain
Acupuncture is an effective short term treatment for patients with chronic neck pain, but there is only limited evidence for its long term effects after five treatments, concludes research in this week's BMJ. A total of 177 patients with chronic neck pain were randomly allocated to five treatments over three weeks. Fifty-six patients received... view more... (2001-06-27)
Drug has ability to cure type of leukemia
In people with chronic myeloid leukemia (CML), the drug Imatinib has been shown to drive cancer into remission, but the disease often returns when treatment is stopped. view more (2007-10-03)
Master regulatory gene found that guides fate of blood-producing stem cells
Researchers from the University of Pennsylvania School of Medicine found that a protein called NF-Ya activates several genes known to regulate the development of hematopoietic stem cells (HSC), or blood-producing stem cells, in bone marrow. view more (2005-08-02)
Predicting quality of life for individuals with chronic pain
People who suffer with chronic pain have a lower quality of life than those with the chronic illness diabetes. view more (2002-11-13)
VIRTUAL FRIEND HELPS YOUNG ASTHMA SUFFERERS
Young people with chronic health problems can benefit from text message services, say researchers this week's BMJ. Doctors in Tayside set up a mobile phone text message service combining reminders to use an inhaler with sport news, celebrity gossip, and horoscopes. The messages were sent by a "virtual friend with asthma" to 30 young... view more... (2002-09-10)
Molecular detectors may refine cancer treatment
University of Florida researchers have successfully used molecular probes to detect subtle differences in leukemia cells from patient samples, an achievement that could lead to more effective ways to diagnose and treat cancer. view more (2007-07-20)
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