Chronic Myeloid Leukemia Current Events | Chronic Myeloid Leukemia News | 7
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St. Jude gene study reveals basis of anticancer drug resistance in childhood leukemia The first analysis of the genetic determinants of resistance to the anti-cancer drug methotrexate in childhood acute lymphoblastic leukemia (ALL) could offer a pathway to predicting such resistance and treatments to overcome it, according to a St. Jude Children's Research Hospital study. view more (2008-04-16)
Can you hear me now? Scientists find previously unknown receptors on adult stem cells For many years, researchers believed that stem cells in the bone marrow spent most of their existence in a slumber-like state, unaware of — and unaffected by — the daily battles fought by the body's immune system. view more (2006-06-21)
Scientists link genetic glitches to common childhood cancer A multicenter team of childhood cancer researchers has discovered two genetic variations linked to an increased risk for acute lymphoblastic leukemia, or ALL, the most common childhood cancer in the United States. view more (2009-08-18)
Discoveries thrust cancer-initiating stem cells into a larger role in cancer biology and treatment Recent discoveries about the role of stem cells in cancer have altered the landscape of cancer research. With each new study, scientists are learning more about cancer-initiating properties of stem cells at organ sites and throughout the body. view more (2007-04-19)
New treatment option breaks Leukemia's resistance to chemotherapy, radiation therapy German researchers set out to outwit cancer tumor cells that have become resistant to chemotherapy or radiation therapy and ended up expanding therapeutic applications of radionuclides in fighting leukemia. view more (2006-06-05)
Novel strategy under study for aggressive leukemia A novel strategy to hopefully beat into oblivion one of the most aggressive forms of acute myelogenous leukemia combines the strengths of some of the newest leukemia agents, researchers say. view more (2007-09-25)
CSHL team develops mouse models of leukemia that predict response to chemotherapy Being able to accurately predict how a given cancer will respond to chemotherapy would spare patients with non-responsive tumors the burden of undergoing toxic and ultimately unhelpful treatment. Just as important, knowing which of a patient's cancer-causing genetic lesions are contributing to drug resistance might help doctors redesign therapy... view more... (2009-04-01)
Scoring system identifies MDS patients who have low-risk disease but a poor prognosis A new scoring system for a form of leukemia known as myelodysplastic syndrome (MDS) identifies patients who appear to have low-risk disease but actually have poor prospects of survival, researchers at The University of Texas M. D. Anderson Cancer Center report online at the journal Leukemia. view more (2007-12-27)
Dasatinib, Nilotinib show strong early results as frontline therapy for chronic myelogenous leukemia Two drugs approved for use as second line therapy for chronic myelogenous leukemia are showing promising results as frontline therapy for newly diagnosed patients in two clinical trials, research teams led by scientists at The University of Texas M. D. Anderson Cancer Center report at the 49th annual meeting of the American Society of Hematology. view more (2007-12-10)
Study shows rituximab effective in treating chronic graft-versus-host disease A study by Dana-Farber Cancer Institute researchers offers the strongest evidence yet of the effectiveness of a novel therapy for chronic graft-versus-host disease (GVHD), a potentially life-threatening complication of donor bone marrow and stem cell transplants. view more (2006-03-27)
Cold homes linked to poor health among the over 50s Older people living in inadequately heated homes are three times as likely to suffer from chronic ill health, reports a study in the Journal of Epidemiology and Community Health. view more (2001-11-09)
Silencing a protein could kill T-Cells, reverse leukemia Blocking the signals from a protein that activates cells in the immune system could help kill cells that cause a rare form of blood cancer, according to physicists and oncologists who combined computer modeling and molecular biology in their discovery. view more (2008-10-23)
Stepping down inhaled steroids can cut side effects A ‘stepdown’ approach to reduce doses of inhaled steroids in patients with chronic asthma can cut the risk of side effects without compromising asthma control, say researchers in this week’s BMJ. view more (2003-05-21)
Survey points out need for education for primary care physicians on rarely seen cancers Many primary care physicians may lack the necessary knowledge when it comes to recognizing the signs, symptoms and making proper diagnoses in cases of blood cancers such as leukemia and lymphoma, a recent survey indicates. view more (2007-12-11)
Nilotinib appears to help chronic myelogenous leukemia patients when standard care fails The targeted agent nilotinib (AMN107) appears to offer striking benefits in patients with chronic myelogenous leukemia (CML) who are resistant to Gleevec, the standard therapy for this cancer. view more (2006-06-15)
New method predicts hip joint decay from chemotherapy Investigators at St. Jude Children's Research Hospital say they have found the best way for predicting when patients will need future surgery to repair hip joints that have deteriorated because of pediatric leukemia or lymphoma treatment. view more (2007-04-20)
May hepatic granulomas be part of the histological spectrum of chronic hepatitis C? While older large series of patients with hepatic granulomas have found sarcoidosis and tuberculosis to be the most common causes of hepatic granulomas, recent works have noted some patients with chronic hepatic C and hepatic granulomas and no other obvious associations. view more (2008-12-29)
Largest study of unrelated bone marrow transplantation for leukemia serves as benchmark Together with 16 other institutions in the United States, University of Minnesota researchers led the largest study to date in patients with leukemia and related disorders undergoing bone marrow transplantation from unrelated donors. view more (2005-08-03)
Syracuse University researchers discover new way to attack some forms of leukemia Each year, some 29,000 adults and 2,000 children are diagnosed with leukemia, a form of cancer that is caused by the abnormal production of white blood cells in the bone marrow. view more (2008-10-29)
Syracuse University research team discovers switch that causes the body to produce cancerous cells A team of Syracuse University researchers discovered a second molecular switch within the Mixed Lineage Leukemia protein complex that they believe could be exploited to prevent the overproduction of abnormal cells that are found in several types of cancer, including leukemia. view more (2009-09-04)
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