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A novel method to measure circadian cycles The variation in individual circadian rhythms is an anecdotal as well as experimentally verified fact. But, until now, to systematically study circadian differences (and thereby hope to rout out the underlying genetic causes), scientists have had to rely on prolonged behavioural observation. view more (2005-09-27)
New fruit fly protein illuminates circadian response to light Researchers at the University of Pennsylvania School of Medicine have identified a new protein required for the circadian response to light in fruit flies. view more (2006-06-30)
First molecular evidence of body's internal clock in controlling blood pressure It has been known for decades that heart attacks and strokes occur most frequently in the early-morning hours. Now, researchers at the University of Pennsylvania School of Medicine have provided the first evidence for the role of our body's internal molecular clock in controlling blood pressure and a mechanism by which this occurs. view more (2007-02-20)
A resetting signal keeps circadian rhythm on track in Drosophila fruit flies A Brandeis University study published this week in Nature shows for the first time that a molecular signal maintains coherence among brain clock cells that regulate daily activity of Drosophila melanogaster (fruit flies). view more (2005-11-10)
Research leads to healthful strategies for re-setting the body's clock Everyone is equipped with a biological clock, a region in the brain the size of a corn kernel, which dictates our sleep-wake cycles, and plays a major role in our physical and mental health. view more (2006-03-23)
Keeping the body in sync — The stability of cellular clocks A study in Switzerland uses the tools of physics to show how our circadian clocks manage to keep accurate time in the noisy cellular environment. view more (2007-03-13)
Mood Lighting: Penn Researchers Determine Role of Serotonin in Modulating Circadian Rhythm Researchers at the University of Pennsylvania School of Medicine have determined how serotonin decreases the body's sensitivity to light and that exposure to constant darkness leads to a decrease in serotonin levels in the brain of fruit flies. view more (2005-07-11)
MicroRNAs grease the cell's circadian clockwork Most of our cells possess an internal clock, a group of genes displaying a cyclic expression pattern that reaches a peak once a day. view more (2009-06-01)
Missing or mutated 'clock' gene linked to vascular disease The circadian clocks that set the rhythmic motion of our bodies for wakeful days and sleepy nights can also set us up for vascular disease when broken, Medical College of Georgia researchers say. view more (2009-03-26)
Early to bed, early to rise In an upcoming G&D paper, a team of German scientists presents a genetic basis for understanding human morning lark behavior. Dr. Achim Kramer (Charité Universitaetsmedizin Berlin) and colleagues have uncovered a genetic cause for the human familial advanced sleep phase syndrome (FASPS), which causes people to both go to sleep and wake up... view more... (2006-09-20)
Networking around the clock A Brandeis University study published in Cell this week shows for the first time experimentally that the circadian cells in fruit flies function as a network that enables the insects to adapt their behavior according to seasonal changes. view more (2007-04-09)
Chemotherapy for breast cancer is associated with disruption of sleep-wake rhythm in women A study in the Sept.1 issue of the journal Sleep shows that the sleep-wake activity rhythms of breast cancer patients are impaired during the administration of chemotherapy. view more (2009-09-01)
Rockefeller researchers discover a biological clock within a clock Just as a pocket watch requires a complex system of gears and springs to keep it ticking precisely, individual cells have a network of proteins and genes that maintain their own internal clock - a 24-hour rhythm that, in humans, regulates metabolism, cell division, and hormone production, as well as the wake-sleep cycle. view more (2006-01-13)
Study identifies food-related clock in the brain In investigating the intricacies of the body's biological rhythms, scientists at Beth Israel Deaconess Medical Center (BIDMC) have discovered the existence of a "food-related clock" which can supersede the "light-based" master clock that serves as the body's primary timekeeper. view more (2008-05-23)
Gene controlling circadian rhythms may be involved in onset of bipolar disorder Disrupt the gene that regulates the biological clocks in mice and they become manic, exhibiting behaviors similar to humans with bipolar disorder, UT Southwestern Medical Center researchers have found. view more (2007-03-20)
Seasonal weight changes linked to metabolic syndrome Seasonal changes in weight increase the risk for metabolic syndrome, a group of scientists from National Public Health Institute, Helsinki, Finland, reports in a study published in the January 23 issue of the online, open-access journal PLoS ONE. view more (2008-01-23)
Plants in the fourth dimension As anyone who has suffered from jetlag knows, we have internal clocks that tell us when to sleep and wake, and we can be miserable when these are disrupted. view more (2008-07-01)
New paper describes connections between Circadian and metabolic systems A paper by University of Notre Dame biologist Giles Duffield and a team of researchers offers new insights into a gene that plays a key role in modulating the body's Circadian system and may also simultaneously modulate its metabolic system. view more (2009-11-13)
Renal colic shows a circadian pattern Renal colic (spasms of pain in the back usually caused by kidney stones) occurs in a circadian pattern, finds a study in this week’s BMJ. view more (2002-03-27)
UNC study: Tinkering with the circadian clock can suppress cancer growth Researchers at the University of North Carolina at Chapel Hill have shown that disruption of the circadian clock - the internal time-keeping mechanism that keeps the body running on a 24-hour cycle - can slow the progression of cancer. view more (2009-02-04)
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