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Study identifies pathway required for normal reproductive development
Massachusetts General Hospital (MGH) clinical researchers, in collaboration with basic scientists from the University of California, Irvine (UC Irvine) have identified a new molecular pathway required for normal development of the reproductive, olfactory and circadian systems in both humans and mice.   view more (2007-10-16)

Thale cress goes on the defensive
Thale cress has a complicated defence technique against insects and microorganisms that use the plant as a source of food.   view more (2007-05-15)

Scripps research scientists model 3D structures of proteins that control human clock
In an Early Edition issue of The Proceedings of the National Academy of Sciences (PNAS) on April 9, 2009, the researchers report that they have been able to determine the molecular structure of a plant photolyase protein that is surprisingly similar to two cryptochrome proteins that control the "master clock" in humans and other mammals.   view more (2009-04-13)

U-M discovery about biological clocks overturns long-held theory
University of Michigan mathematicians and their British colleagues say they have identified the signal that the brain sends to the rest of the body to control biological rhythms, a finding that overturns a long-held theory about our internal clock.   view more (2009-10-09)

Plants grow bigger and more vigorously through changes in their internal clocks
Hybrid plants, like corn, grow bigger and better than their parents because many of their genes for photosynthesis and starch metabolism are more active during the day, report researchers from The University of Texas at Austin in a new study published in the journal Nature.   view more (2008-11-24)

Monitoring the response to vaccination against melanoma
A new study published in PLoS Medicine this week describes a way to measure the immune response in people treated with an experimental vaccine to melanoma.   view more (2005-09-20)

Sodium, prostaglandin may be keys to successful treatment for some bedwetters
Children with a form of bedwetting that does not respond to a common medication have more sodium and urea in their nighttime urine, possibly because of an imbalance of prostaglandin, a hormone-like substance, a new study has found.   view more (2006-12-01)

Body clock linked to diabetes and high blood sugar in new study
Diabetes and high levels of blood sugar may be linked to abnormalities in a person's body clock and sleep patterns, according to a genome-wide association study published today in the journal Nature Genetics.    view more (2008-12-08)

IL-21 receptor plays an essential role in the Th2 immune response
During the immune response cells known as Th2 cells express a variety of cytokines (e.g. interleukin-4, -5, and -13), many of which stimulate B cells to proliferate and produce antibodies.   view more (2006-06-16)

Light Receptors in Eye Play Key Role in Setting Biological Clock, Study Shows
Biologists at the University of Virginia have discovered a switching mechanism in the eye that plays a key role in regulating the sleep/wake cycles in mammals.   view more (2008-08-18)

Experts research world-first tests for allergic reactions to medication
It is estimated that up to 10,000 UK hospital patients each year suffer an allergic reaction to anaesthetics, and that one in every 100-200 consumers of penicillin has an allergic response to it. Allergic reactions to fairly common medications generally occur unexpectedly and often within minutes of drug administration, but there are few... view more... (1999-05-24)

Complete response with oblimersen combination improves survival of CLL patients
Relapsed chronic lymphocytic leukemia (CLL) patients who had a complete response to combination therapy that included the drug oblimersen survived significantly longer than patients treated with chemotherapy alone, a team led by researchers at The University of Texas M. D. Anderson Cancer Center reports at the 49th Annual Meeting of the American... view more... (2007-12-10)

EXPOSURE TO CATS CAN INDUCE ASTHMA TOLERANCE (p 752)
Children exposed to cat allergens at home can produce an immune response without developing asthma, report authors of a study in this week’s issue of THE LANCET. However, in some children, exposure to cat allergens remains the highest single risk factor for asthma. Although asthma is strongly associated with immediate hypersensitivity to... view more... (2001-03-07)

Gulf War Syndrome triggered by smells of war
The persistent symptoms of Gulf War Syndrome in the home years later could well be due to a sickness response to the body's immune system being conditioned to the smells, tastes and sounds of war.   view more (1998-12-03)

Acute Sleep Deprivation Leads To Changes In Nighttime Urine
Our body's production of urine follows a circadian rhythm. During the day, we experience greater urinary frequency; at night, urine production declines, enabling us to get uninterrupted sleep.   view more (2007-08-09)

To sleep, perchance to dream: New insight into melatonin production
In the April 1 issue of G&D, a Korean research team led by Dr. Kyong-Tai Kim (Pohang University) describes how melatonin production is coordinated with the body's natural sleep/wake cycles.   view more (2007-04-02)

WUSTL research finds individual cells isolated from the biological clock can keep daily time, but are unreliable
Alexis Webb enters a small room at Washington University in St. Louis with walls, floor and ceiling painted dark green, shuts the door, turns off the lights and bends over a microscope in a black box draped with black cloth. Through the microscope, she can see a single nerve cell on a glass cover slip glowing dimly.    view more (2009-09-10)

Disturbed sleep is prevalent in widowed seniors
Widowed seniors are more likely to have disrupted sleep when studied at least four months after the loss event, according to a research abstract that will be presented on Wednesday at SLEEP 2008, the 22nd Annual Meeting of the Associated Professional Sleep Societies (APSS).   view more (2008-06-11)

High rates of skin cancer among airline pilots
Rates and types of cancer were assessed in 458 pilots, 265 of whom flew the national Icelandic airline across European and transAtlantic routes. These were then compared with the rates of cancer expected to develop in the population as a whole, gathered from data supplied by the national cancer registry, according to age.   view more (2000-02-14)

Immune responses spread from one protein to another in type 1 diabetes
Type 1 diabetes (T1D) is caused by the immune system inappropriately attacking the cells in the pancreas that produce insulin, the hormone that controls blood sugar levels.   view more (2006-12-04)
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