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Who is the arch-criminal in the development of hepatopulmonary syndrome?
The hepatopulmonary syndrome (HPS) develops when an arterial oxygenation deficiency occurs due to intra-pulmonary vascular dilatations that are often associated with severe hepatic disease. HPS occurs in 15-20% of patients with liver cirrhosis undergoing evaluation for orthotopic liver transplantation.   view more (2007-12-20)

p90RSK: A new therapeutic target for liver fibrosis?
Cirrhosis is a world wide, bad prognosis liver disease and characterized by excessive collagen deposition and liver function damage.   view more (2009-05-13)

The hepatitis healing power of blueberry leaves
A chemical found in blueberry leaves has shown a strong effect in blocking the replication of the Hepatitis C virus, opening up a new avenue for treating chronic HCV infections, which affect 200 million people worldwide and can eventually lead to cirrhosis and liver cancer.    view more (2009-08-10)

The risk factors of idiopathic pulmonary fibrosis in HCV patients
Hepatitis C virus (HCV) is one of the more common causes of chronic liver disease in world with a variety of extrahepatic complications such as essential mixed cryoglobulinemia, membranoproliferative glomerulonep hritis, autoimmune thyroiditis, sialadenitis, and cardiomyopathy.   view more (2008-10-23)

To protect against liver disease, body puts cells 'under arrest'
A stable form of cell-cycle arrest known to offer potent protection against cancer also limits liver fibrosis, a condition characterized by an excess of fibrous tissue, according to a new report in the August 22nd Cell, a Cell Press publication.   view more (2008-08-22)

Optimal systemic and splanchnic hemodynamic state after living-donor liver transplantation
Almost all adult recipients who undergo LDLT develop liver cirrhosis with long-term portal hypertension. Portal hypertension results in vascular dilatation and collateral pathways. Thus, various alterations in systemic hemodynamics and splanchnic circulation occur, and adult recipients often present characteristic hemodynamics before LDLT.   view more (2007-11-14)

Protective action of a molecule in inflammatory processes discovered
Henar Hevia Pérez, researcher in the area of Genic Therapy and Hepatology at the Applied Medicine Research Centre (CIMA)of the University of Navarra, has discovered the protective role of the methylthioadenosine (MTA) molecule in an in vivo inflammation model.   view more (2006-04-27)

Vitamin D deficiency common in patients with IBD, chronic liver disease
New research presented at the 73rd Annual Scientific Meeting of the American College of Gastroenterology in Orlando found patients with inflammatory bowel disease or chronic liver disease were at increased risk of developing Vitamin D deficiencies. Two separate studies highlight the importance of regular Vitamin D checkups in the evaluation of... view more... (2008-10-06)

New Mayo Clinic MRI technology enables noninvasive liver diagnoses
Two recent Mayo Clinic studies have found that magnetic resonance elastography (MRE), a new imaging technique invented at Mayo Clinic, is an accurate tool for non-invasive diagnosis of liver diseases.   view more (2007-05-23)

Focusing HIV treatment helps control concurrent hepatitis B infection
Prolonged use of highly active antiretroviral therapy (HAART) to treat people infected with both HIV and hepatitis B (HBV) helps to better control the hepatitis B infection and could delay or prevent liver complications.   view more (2009-07-15)

CT colonography detects wide-range of extracolonic abnormalities in elderly patients
CT colonography (CTC), when used in elderly patients, can detect a high number of new and significant abnormalities outside the colon (including cirrhosis and tumors) and is well tolerated, according to a recent study conducted by researchers at St. James's University Hospital in Leeds, United Kingdom (UK).   view more (2007-11-16)

Alcohol Tolerance Switch Found in Fruit Flies
Researchers at North Carolina State University have found a genetic "switch" in fruit flies that plays an important role in making flies more tolerant to alcohol.   view more (2009-10-22)

Interferon as long-term treatment for hepatitis C not effective, report HALT-C researchers
Use of the drug interferon as a long-term maintenance strategy to slow the progression of liver disease associated with the hepatitis C virus is ineffective, UT Southwestern Medical Center researchers and their colleagues from nine other institutions have found in a multicenter study.   view more (2008-12-05)

Study shows positive findings in treating patients with advanced hepatitis C
The hepatitis C therapy peginterferon alfa-2b, when given as low-dose maintenance therapy, can prevent disease progression in certain patients who failed previous interferon-based hepatitis C therapies and have advanced liver disease, according to findings from a large, four-year study presented today at the 43rd annual meeting of the European... view more... (2008-04-25)

Interferon does not slow or stop hepatitis C from worsening, study finds
Interferon does not slow or halt the progression of chronic hepatitis C and advanced liver disease in patients who haven't responded to previous attempts to eradicate the disease, a national study in which the Saint Louis University School of Medicine participated has found.   view more (2007-11-09)

Topical Papers in Biochemical Journal - Selective determination of mitochandrial chelatable iron in viable cells with a new fluorescent sensor
This paper by Petrat and colleagues marks an important advance in our understanding of the regulation of iron in the human body. Real-time changes in the concentration of the ionized form of iron (Fe2+) can now be monitored within the mitochondria of living cells for the first time, thanks to the technique described in this article. For some... view more... (2002-02-08)

Study concludes no racial disparities in long-term outcomes in recipients of liver transplants
New research published in the Journal of the American College of Surgeons shows long-term survival and liver rejection rates are equivalent for African-American liver transplant patients as compared with patients of other races.   view more (2008-05-20)

Drug boosts platelets in hepatitis C patients
It's not a cure, but this may be some of the best news patients infected with the hepatitis C virus (HCV) have heard in a long time: A new drug, eltrombopag, appears to be effective in boosting low platelet counts, one of the major reasons why patients can't endure antiviral treatments.   view more (2007-11-29)

What are the risk factors for rebleeding after negative angiography?
Acute non-variceal gastrointestinal bleeding accounts for approximately 20% of emergency room visits and 5% of admissions.   view more (2009-09-16)

Massive necrosis after trans-catheter treatment is more common in the presence of tumor capsule
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. Prognosis of patients with HCC complicating cirrhosis mainly depends on the tumor growth, progression of the underlying liver disease and the effectiveness of antitumoral treatment.   view more (2007-11-26)
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