Cisplatin Current Events | Cisplatin News | 2
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New platinum-phosphate compounds kill ovarian cancer cells
A new class of compounds called phosphaplatins can effectively kill ovarian, testicular, head and neck cancer cells with potentially less toxicity than conventional drugs, according to a new study published this week in the journal Proceedings of the National Academy of Sciences. view more (2008-11-20)
Therapeutic delivery of a gene to dysfunctional nerves
Medical conditions that affect sensory nerves outside the brain and spinal cord are known as sensory neuronopathies. These conditions, which are extremely painful, include shingles and can be caused by anticancer drugs such as cisplatin. view more (2009-06-16)
Herceptin gives disappointing results in lung cancer trial
Trastuzumab (Herceptin) - a treatment that has increased survival in many breast cancer patients - has failed to live up to hopes that it might also help lung cancer patients. view more (2004-01-08)
Women with advanced ovarian cancer survive longer when treated with paclitaxel (Taxol) and cisplatin than with cyclophosphamide-cisplatin therapy
Embargoed for release: Tuesday 22 October, 09.30 (Europe), 08.30 (GMT) Women with advanced ovarian cancer survive longer when treated with Taxol (paclitaxel) and cisplatin than with cyclophosphamide-cisplatin... view more... (2002-10-19)
Combined Chemotherapy and Radiotherapy for Cervical Cancer Could Increase Survival (p 781)
A systematic review of randomised trials in the past two decades published in this week’s issue of THE LANCET concludes that women given concurrent chemotherapy and radiotherapy for cervical cancer could have an increased survival-rate of 12% compared with patients treated with radiotherapy alone. Cervical cancer is the second most common... view more... (2001-09-05)
Light powered platinum more targeted & 80 times more powerful than similar cancer treatments
Researchers from the Universities of Warwick, Edinburgh, Dundee and the Czech Republic's Institute of Biophysics have discovered a new light-activated platinum-based compound that is up to 80 times more powerful than other platinum-based anti-cancer drugs and which can use "light activation" to kill cancer cells in much more targeted way... view more... (2007-12-26)
Chemo combination improves survival in asbestos-related cancer
People with mesothelioma — a form of cancer associated with asbestos exposure — have a higher survival rate when treated with a combination of two cancer drugs, a large multicenter study finds. view more (2007-02-09)
Testicular cancer patients may be more at risk from the treatment than the cancer returning
Testicular cancer - cure rates now so high patients may be more at risk from the treatment than the cancer returning say researchers view more (2002-02-23)
New chemotherapy regimen prolongs survival in difficult-to-treat childhood brainstem gliomas
Childhood brainstem gliomas (BSGs) are rare but can be very difficult to treat successfully and they tend to have poor survival rates. view more (2007-09-26)
Herceptin effective in breast cancer cells with low HER-2 levels
Northwestern University and Evanston Northwestern Healthcare researchers have discovered that the monoclonal antibody Herceptin (trastuzumab) used in combination with certain cancer chemotherapies effectively treats breast cancer tumors that produce low or undetectable amounts of the HER-2 oncogene but overexpress the growth factor heregulin... view more... (2006-08-11)
New clinical trial for patients with asbestos-associated lung cancer
The Mesothelioma Center within the Herbert Irving Comprehensive Cancer Center at NewYork-Presbyterian Hospital and Columbia University Medical Center is now recruiting patients for a clinical research study of a new targeted radiation and chemotherapy protocol for pleural mesothelioma, a cancer of the lung's lining that is almost always caused by... view more... (2008-06-26)
Enzyme crystal structure reveals 'unexpected' genome repair functions
The research looked at XPB helicase from an archaea, a single cell organism similar to bacteria. Helicases are enzymes that unwind or separate the strands of the nucleic acid double helix, an action that is critical to transcription and nucleotide excision repair (NER), as well as other cell processes. view more (2006-04-07)
New cancer drug delivery system is effective and reversible
For cancer drug developers, finding an agent that kills tumor cells is only part of the equation. The drug must also spare healthy cells, and - ideally - its effects will be reversible, to cut short any potentially dangerous side effects. view more (2009-08-07)
Avantogen and Innovate announce ASCO abstracts
Avantogen Limited ("Avantogen", ASX:ACU), Sydney, Australia and San Diego, CA, and Innovate Oncology, Inc ("Innovate"; IOVO:OTCBB), New York, today announced that 2 abstracts reporting on the evaluation of the use of RP101 in the treatment of patients with pancreatic cancer. view more (2006-06-12)
Intraperitoneal chemotherapy administration prolongs survival for women with advanced ovarian cancer
A study featured in this month's edition of Gynecologic Oncology examines the challenges associated with the administration of intra-abdominal chemotherapy, also known as intraperitoneal (IP) chemotherapy. view more (2006-01-05)
Intravenous chemoradiation effective for inoperable head, neck cancer; easier for patients, doctors
Chemoradiation (radiation and chemotherapy given at the same time) given through a needle or tube inserted into a vein (intravenous) is as effective as treatment given directly to the tumor through a tube inserted into an artery (intra-arterial) for patients with inoperable head and neck cancer. view more (2006-11-07)
No benefit to increasing dose intensity of chemotherapy in osteosarcoma, study finds
A dose-intensive regimen of the chemotherapy drugs cisplatin and doxorubicin offered no clinical benefit over standard doses of the chemotherapy drugs in patients with a bone cancer called osteosarcoma, according to results from a randomized trial in the January 17 issue of the Journal of the National Cancer Institute. view more (2007-01-17)
UC Davis researchers discover genetic switch involved in cells' response to radiation therapy
UC Davis Cancer Center researchers have discovered a genetic switch that causes cancer cells to become more sensitive to a drug administered to enhance radiation therapy effectiveness. view more (2005-11-17)
UNC study supports role of circadian clock in response to chemotherapy
For years, research has hinted that the time of day that cancer patients receive chemotherapy can impact their chances of survival. But the lack of a clear scientific explanation for this finding has kept clinicians from considering timing as a factor in treatment. view more (2009-01-13)
Study supports DNA repair-blocker research in cancer therapy
Scientists at Dana-Farber Cancer Institute have uncovered the mechanism behind a promising new approach to cancer treatment: damaging cancer cells' DNA with potent drugs while simultaneously preventing the cells from repairing themselves. view more (2009-08-18)
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