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Defeating nicotine's double role in lung cancer
A lung cancer treatment that inhibits nicotine receptors was shown to double survival time in mice, according to Italian researchers.   view more (2009-06-09)

New protein target may advance design of HIV and cancer drugs
Using small molecules containing platinum, Virginia Commonwealth University Massey Cancer Center researchers have created a process to inhibit a class of proteins important in HIV and cancer.   view more (2006-05-31)

miR-196a promotes the metastases of tumors
MicroRNAs are small RNA molecules of 20-25 nucleotides length, regulating gene expression by inhibition of transcription or translation of proteins.   view more (2009-05-13)

Analysis shows combining sorafenib with carboplatin/paclitaxel adds no benefit in lung cancer
A clinical trial evaluating the benefit of adding the drug sorafenib to the combination of carboplatin/paclitaxel chemotherapy for lung cancer patients has been stopped based on results from an interim analysis, after an independent data monitoring committee concluded that the study would not meet its primary endpoint of improved overall survival.   view more (2008-04-28)

Gene for neat repair of DNA discovered
Researchers from the Erasmus University in Rotterdam have demonstrated that a gene helps in the neat repair of DNA. Without this gene the body would repair damaged DNA in a careless manner more often. This causes new damage, which can lead to cancer. The careless repair of damaged DNA can cause mutations and can result in cancer. Cell biologists... view more... (2002-01-24)

Advanced therapy offers cure for relapsed cancer patient
Testicular cancer patients who do not respond to traditional therapy can be cured with high-dose chemotherapy and a stem cell transplant.   view more (2007-07-26)

Nanoparticle-delivered 'suicide' genes slowed ovarian tumor growth
Nanoparticle delivery of diphtheria toxin-encoding DNA selectively expressed in ovarian cancer cells reduced the burden of ovarian tumors in mice, and researchers expect this therapy could be tested in humans within 18 to 24 months, according to a report in Cancer Research, a journal of the American Association for Cancer Research.    view more (2009-07-30)

Dangerous glucose-hungry cervical tumors can be detected using PET scans
Cervical cancers that take up a lot of blood sugar, or glucose, are more resistant to treatment than those that are less glucose-hungry, according to research at Washington University School of Medicine in St. Louis.   view more (2006-03-31)

Blocking one protein helps cancer cells die of natural causes
Researchers have identified a protein fragment that keeps at least one major tumor suppressor gene from preventing cancer like it should. The fragment belongs to a class of proteins known as apoptotic enhancers (ASPP), named for their ability to stimulate programmed cell death, or apoptosis, by the p53 gene. But a study published in Nature... view more... (2003-01-08)

Chemotherapy after surgery extends survival for patients with advanced endometrial cancer
A new study has shown for the first time that giving two chemotherapy drugs to women with advanced endometrial cancer after surgery reduced the risk of recurrence by 29% and extended survival by 32% compared with women who received whole abdominal irradiation.   view more (2005-12-06)

Intensity-modulated radiation therapy reduces side effects for cervical cancer
Preliminary results from a University of Pittsburgh study evaluating extended-field intensity-modulated radiation therapy (IMRT) for cervical cancer found that it resulted in significantly reduced side effects and outcomes comparable to standard radiotherapy.   view more (2006-11-08)

International Study Suggests Carboplatin Could Be First-line Chemotherapy Drug For Ovarian Cancer
Results of an international study in this week's issue of THE LANCET suggest that the drug carboplatin could become a first-line chemotherapeutic agent for the treatment of ovarian cancer. Carboplatin was found to be less toxic, although it had no overall survival benefit, compared with other drugs assessed in the study. Ovarian cancer is the... view more... (2002-08-14)

Mystery solved: Gold's power against autoimmune diseases defined
Gold compounds have been used for the treatment of rheumatoid arthritis and other autoimmune diseases for more than 75 years, but until now, how the metals work has been a mystery.   view more (2006-02-27)

U of I scientist develops enzyme inhibitor that may slow cancer growth
University of Illinois scientist Tim Garrow, in collaboration with Jiri Jiracek of the Czech Academy of Sciences, has applied for a provisional patent on a class of chemicals that has future therapeutic uses in medicine, specifically cancer treatment.   view more (2006-07-07)

Researchers find the mechanism by which cells resist chemotherapy
In his paper, to be published in The EMBO Jorunal, Dr SurrallĂ©s describes how proteins of the Fanconi/BRCA pathway recognise the presence of genetic mutations in order to repair them.   view more (2007-03-05)

Hearing loss from chemotherapy underestimated
By 14, Peter Johnson had survived brain cancer and a relapse of the disease in his shoulder. But it was treatment for the last tumor that would create his life's greatest challenges.   view more (2005-12-12)

Researchers find docking sites for glucocorticoid receptor and Hsp90
University of Oregon researchers have identified protein interactions that regulate the response of cells to steroid hormones. The discovery, they say, could lead to new ways to boost the effectiveness and reduce undesired side effects of steroid-hormone treatments and cancer drugs.   view more (2006-11-21)
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