Cistic Fibrosis Current Events | Cistic Fibrosis News | 6
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First different black/white mechanism in pulmonary fibrosis/scleroderma identified
Of the more than 40,000 persons who die each year in the U.S. from pulmonary fibrosis, the mortality rate among African-Americans is twice as high Caucasians. view more (2006-04-05)
Peptide discovered in scorpion venom may hold key to secretory diseases
Researchers have discovered a peptide in scorpion venom that may hold the key to understanding and controlling cystic fibrosis and other secretory diseases. view more (2008-02-15)
Scientists determine structure of enzyme that disrupts bacterial virulence
A team of biomedical researchers from Brandeis University and the University of Texas at Austin has determined the first 3-dimensional structure of an enzyme that may be pivotal in preventing certain bacterial infections in plants, animals and humans. view more (2005-08-31)
Newborns with respiratory distress potentially have rare genetic disease
Newborns with respiratory distress should be evaluated for primary ciliary dyskinesia, a rare genetic disease that has features similar to cystic fibrosis, says Thomas Ferkol, M.D., from Washington University School of Medicine in St. Louis. view more (2007-02-21)
New test detects cirrhosis of the liver in an early stage
Ghent researchers have developed a new and easy method of detecting cirrhosis of the liver. This major finding helps predict the evolution of chronic liver disease, allowing physicians to start proper treatment early on. Patients suffering from this serious, progressive disease in its cirrhosis stage have a high chance of developing liver cancer.... view more... (2004-03-08)
Advanced genomics and proteomics improve the diagnosis and treatment of a deadly lung disease
In an article in the Jan. 15 issue of the American Journal of Respiratory Critical Care Medicine, University of Pittsburgh researchers report that a serious, life-threatening form of pulmonary fibrosis, called idiopathic pulmonary fibrosis, lacks all the hallmarks of inflammation and is probably unnecessarily treated with anti-inflammatory drugs. view more (2006-01-12)
Link between chronic kidney disease and oxygen-deprived tissue
Researchers at the University of Pennsylvania School of Medicine have discovered how low-oxygen conditions can worsen chronic kidney disease (CKD). view more (2007-12-19)
Study shows how carbon nanotubes can affect lining of the lungs
Carbon nanotubes are being considered for use in everything from sports equipment to medical applications, but a great deal remains unknown about whether these materials cause respiratory or other health problems. view more (2009-10-26)
Children with cystic fibrosis not well covered by guidelines for vitamin D needs
Existing recommendations for treating vitamin D deficiency in children with cystic fibrosis (CF) are too low to cover the serious need, leaving most at high risk for bone loss and rickets, according to researchers at Johns Hopkins Children's Center. view more (2008-10-10)
Rare Lung Disease Cells Indicate Higher Death Risk
Large numbers of certain cells in the lungs of patients diagnosed with idiopathic pulmonary fibrosis may increase their chance of death, UC researchers have discovered. view more (2008-01-17)
A rigorous method for liver biopsy
Liver biopsy is still considered the gold standard for grading, staging and "stad-ging" the chronic liver disease. In addition, it remains a primary source for acquiring new knowledge on the liver pathology. view more (2009-01-05)
PTC124 shows activity in cystic fibrosis; Phase 2 proof-of-concept data published in Lancet
New phase 2 data published today in The Lancet show that the investigational oral drug PTC124 demonstrates activity in nonsense-mutation cystic fibrosis (CF). The data show that treatment with PTC124 results in statistically significant improvements in the chloride channel function of patients with nonsense-mutation CF. The study was conducted at... view more... (2008-08-21)
Biomarkers identified for idiopathic pulmonary fibrosis
The first evidence of a distinctive protein signature that could help to transform the diagnosis and improve the monitoring of the devastating lung disease idiopathic pulmonary fibrosis (IPF) is being reported by University of Pittsburgh School of Medicine researchers in this month's edition of PLoS Medicine, an open-access journal of the Public... view more... (2008-04-29)
U-M scientists target key cells and signals that trigger pulmonary fibrosis
Scientists at the University of Michigan Medical School have identified biochemical signals that attract pathogenic cells to damaged lung tissue - one of the first steps in a chain of events leading to a lethal disease called idiopathic pulmonary fibrosis or IPF. view more (2006-05-24)
Rice breakthrough could prevent multiple fibrotic diseases
A scientific breakthrough at Rice University could lead to the first treatment that prevents the build-up of deadly scar tissue in a broad class of diseases that account for an estimated 45 percent of U.S. deaths each year. view more (2007-01-19)
Mild hepatitis C infection will rapidly worsen in one in three people affected
Mild hepatitis C infection will rapidly worsen in one in three of those affected, suggests research in Gut. This is particularly likely in those who are older when first infected, and those who already have a degree of inflammation and scar tissue (fibrosis) in their liver at diagnosis. The viral liver infection hepatitis C (HCV) is mainly passed... view more... (2004-02-11)
Boosting its infectivity turns benign virus into good gene therapy carrier for cystic fibrosis
Researchers from the University of California, Berkeley, and the University of Iowa have turned a relatively benign virus into a highly infectious form that is ideal as a carrier for gene therapy. view more (2009-02-17)
Women with cystic fibrosis can have safe and successful fertility treatment
Women with cystic fibrosis can have fertility treatment to help them have babies without any long-term adverse effects on either themselves or their children. view more (2009-06-30)
Penn pairs chronically ill patients with medical students to create better doctor
Doctors-in-training - like Christopher Guerry, a second-year medical student at Penn - are learning what it's like to live with cystic fibrosis (CF), and many other chronic health conditions. They're shadowing patients with chronic conditions such as HIV, asthma and kidney failure. view more (2006-03-06)
Breaking the 'mucus barrier' with a new drug delivery system
Chemical engineers from Johns Hopkins University have broken the "mucus barrier," engineering the first drug-delivery particles capable of passing through human mucus - regarded by many as nearly impenetrable - and carrying medication that could treat a range of diseases. Those conditions include lung cancer, cervical cancer and cystic... view more... (2008-08-20)
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