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Patients unaware of risks and purpose of research even after informed consent As many as two-thirds of critically ill patients who consented to take part in a clinical trial do not remember the purpose and risks of the research shortly after. view more (2006-12-08)
Patients should be more involved in the clinical trial process Patients should be treated as participants rather than subjects during clinical trials, suggest researchers in this week’s BMJ. view more (2002-12-04)
Enrollment in cancer trials not linked to better health outcomes (p 263) The widely held view that people with cancer who participate in clinical trials have better treatment outcomes is disputed by US authors of a study in this week's issue of THE LANCET. Less than 5% of adults with cancer are enrolled into clinical trials. Steven Joffe from the Dana-Farber Cancer Institute, Boston, USA, and colleagues reviewed 26... view more... (2004-01-21)
Edmonton Protocol clinical trial shows islet transplantation shows promising results The Edmonton Protocol clinical trial, led by University of Alberta researcher Dr. James Shapiro, shows islet transplantation is a promising procedure for certain patients with severe Type 1 Diabetes. view more (2006-09-28)
Warts vaccine -- 1 of many in pipeline A clinical trial treating the papillomaviruses responsible for genital warts was on target at the halfway mark, according to Australian of the Year 2006 Professor Ian Frazer and trial manager, sexual health specialist Dr David Jardine. view more (2007-05-10)
Potential prostate cancer treatment improvements discovered by researchers at Cedars-Sinai In a study to be published in the April, 2006 issue of the British Journal of Urology International, researchers at Cedars-Sinai Medical Center have shown that Raloxifene, a drug commonly used to treat osteoporosis, has a potential clinical benefit in treating men with prostate cancer. view more (2006-03-22)
Stanford study finds no conclusive benefit from treating kleptomania A small clinical trial of a medication to treat kleptomania has failed to find any conclusive benefit for patients with the impulsive stealing disorder, according to researchers at the Stanford University School of Medicine. view more (2007-03-14)
Screening may over-diagnose 1 in 10 breast cancers Screening women for breast cancer could result in a 10% rate of over-diagnosis, finds a study published online by the BMJ today. view more (2006-03-03)
Novel therapy may prove effective in treatment of 30 percent of cancers A ground-breaking Canada-wide clinical trial led by Dr. Katherine Borden, at the Institute for Research in Immunology and Cancer (IRIC) of the Université de Montréal, has shown that a common anti-viral drug, ribavirin, can be beneficial in the treatment of cancer patients. view more (2009-05-14)
Hospitals that participate in clinical trials may provide better patient care Hospitals that participate in clinical trials appear to provide better care for patients with heart attacks or other acute heart events and have lower death rates than hospitals that do not participate in clinical trials, according to a report in the March 24 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. view more (2008-03-25)
First large-scale trial of genetically personalised treatment for breast cancer to start soon Hamburg, Germany: The first large-scale independent trial to study the role of molecular tumour signatures in breast cancer will get underway in the coming year, scientists announced today (Friday March 19) at the 4th European Breast Cancer Conference. TRANS-BIG, a translational research network involving about 40 partners from... view more... (2004-03-17)
Health State Values for Patients with CAD Vary According to the Measure Used to Generate Them A recent study published in the journal Value in Health presents the first attempt to compare two instruments using a population with coronary artery disease (CAD) enrolled in a multinational, randomized, double-blind clinical trial. The objective of the study was to compare the calculated HUI3 and the SF-6D values in CAD patient population. view more (2004-11-10)
TB vaccine developed at McMaster University in Canada McMaster University researchers are about to launch Canada's first tuberculosis (TB) vaccine clinical trial with a vaccine totally designed, manufactured and tested within McMaster. view more (2009-03-20)
South African Geraniums Effective in Treatment of Adults with Acute Bronchitis A recent clinical trial in Europe showed that EPs® 7630, a remedy made from the roots of Pelargonium sidoides-a species of geranium unique to South Africa, is an effective alternative treatment of acute bronchitis. view more (2005-12-14)
First clinical trial of gene therapy for childhood blindness The first clinical trial to test a revolutionary treatment for blindness in children has been announced by researchers at UCL (University College London). view more (2007-05-02)
Vaccine improves event-free survival for leukemia patients Patients whose immune system responded to a peptide vaccine for leukemia enjoyed a median remission that was more than three times longer than non-responders, a team led by researchers at The University of Texas M. D. Anderson Cancer Center reports at the 49th Annual Meeting of the American Society of Hematology. view more (2007-12-10)
Screening for aortic aneurysms is cost effective Routine screening for aortic aneurysms in older men is cost effective, according to a study in this week's BMJ. Using data from a large randomised trial, researchers assessed the cost effectiveness of ultrasound screening for abdominal aortic aneurysms in 67,800 men aged 65-74 years for up to four years. Over four years, there were 47 fewer deaths... view more... (2002-11-13)
MAJOR TRIAL WILL LOOK AT BEST WAYS TO FEED STROKE PATIENTS Dr Martin Dennis, Reader in Stroke Medicine and FOOD Trial Clinical Co-ordinator at the Neurosciences Trials Unit, explains: "Stroke affects approximately 15,000 people in Scotland every year and accounts for about 5% of NHS resources. Currently, there are no definitive recommendations for feeding a patient with stroke, although one of the... view more... (1999-06-21)
1 in 10 advanced colon cancer patients worry about prescription drug costs The vast majority of advanced colon cancer patients in a clinical trial were not concerned about the cost of prescription drugs for managing chemotherapy side effects, such as infection, pain and nausea and few adopted strategies to reduce drug cost burdens after joining the clinical trial. view more (2009-06-01)
New technology could improve clinical trial recruitment Electronic medical records are touted as a great way to prevent medical errors, but researchers are reporting that this new technology may also be just what the doctor ordered for clinical trial recruitment. view more (2005-10-25)
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