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Part of drug trial for patients with atrial fibrillation discontinued
Study treatments for the ACTIVE W trial of the ACTIVE (Atrial Fibrillation Clopidogrel Trial with Irbesartan for Prevention of Vascular Events) program have been discontinued due to a significant difference in efficacy, in favour of the standard oral anticoagulation (OAC) over antiplatelet therapy (clopidogrel plus aspirin). view more (2005-09-07)
HIV integrase inhibitor effective for patients beginning antiretroviral treatment
A member of a new class of antiretroviral drugs is safe and effective for patients beginning treatment against HIV, according to researchers who have completed a two-year multisite phase III clinical trial comparing it with standard antiretroviral drugs. view more (2009-08-03)
Three-year SAPPHIRE and US carotid feasibility trials demonstrate durability of carotid stenting
Preliminary three-year data from the SAPPHIRE and final three-year data from the U.S. Carotid Feasibility Study (USFS) presented at the 2005 Transcatheter Cardiovascular Therapeutics meeting, demonstrate the long-term durability of carotid artery stenting (CAS) for the prevention of stroke versus carotid endarterectomy (CEA) in high risk surgical... view more... (2005-10-19)
Digital Mammography Trial Results Announced
Preliminary results from a large, clinical trial of digital vs. film mammography show no difference in detecting breast cancer for the general population of women in the trial. view more (2005-09-19)
Study finds flaws in cancer clinical trials
Cancer research and drug development are yielding more sophisticated candidate therapies, but investigators' methods to test them haven't kept pace, according to researchers at Memorial Sloan-Kettering Cancer Center. view more (2007-02-02)
Encouraging results from validation study give green light for a trial of personalised treatment in breast cancer
The overall performance of the gene signature to be used in the first large-scale trial to study the role of such tumor signatures in breast cancer is encouraging and gives the green light to start the trial proper, Dr. Martine Piccart, head of the medical oncology department at the Institut Jules Bordet in Brussels, Belgium, told the San Antonio... view more... (2004-12-06)
Trial examines diaphragm use in preventing HIV in women
A clinical trial involving 5,045 women in South Africa and Zimbabwe found no statistical difference in the rate of new HIV infections in the two study arms: those who received a diaphragm plus lubricant along with male condoms for their partners and those who only received male condoms. view more (2007-07-13)
Promising early evidence of the superior benefits of drug therapy for diabetic eye disease
A JDRF collaboration between Johns Hopkins researchers and Genentech has shown that a drug for the treatment of diabetic eye disease has performed better in clinical trials than the current standard treatment using laser surgery. view more (2008-04-30)
Results of phase I trial of novel herbal therapy for men at high risk of prostate cancer
Results of a phase I clinical trial of a novel herb-based therapeutic called Zyflamend have demonstrated that the therapy is associated with minimal toxicity and no serious adverse events in men at high-risk for developing prostate cancer. view more (2009-05-26)
Antioxidant Selenium Offers No Heart-Disease Protection
Selenium does not protect against cardiovascular disease, despite its documented antioxidant and chemopreventive properties, analysis of a randomized placebo-controlled clinical trial covering 13 years has shown. view more (2006-04-26)
Trial stops after stroke and mortality significantly reduced by blood
An international trial looking at the benefits of giving blood-pressure lowering medication to elderly patients has stopped early, after researchers observed significant reductions in overall mortality in those receiving treatment. view more (2007-08-07)
Urologist uses Botox to treat debilitating condition
Eight years ago, Lynette Kunz suffered a severe spinal cord injury that left her a quadriplegic and sufferer of involuntary bladder contractions. The condition constantly interfered with her daily life. view more (2007-12-06)
Munich Biotech reports additional positive data from MBT- 0206 Phase I trial
Continued Tolerability, Quality of Life Improvement, Stabilization and Regression Seen in Cancer Patients on Extension Past Phase I Clinical Trials Munich, March 25th, 2004 - Munich Biotech AG has announced details of results presented during a recent congress of clinical investigators, reporting on results of Phase I trials of MBT-0206 in cancer... view more... (2004-03-25)
Extra 'STICH' in bypass adds no benefit to quality of life
A surgical procedure to resize an enlarged, weakened heart muscle during coronary bypass surgery for heart failure adds cost and risk but doesn't offer patients any additional benefit when compared with those who received bypass procedure alone, according to researchers from the Duke Clinical Research Institute (DCRI). view more (2009-03-30)
UI Researchers Studying Novel Therapy For Prostate Cancer
A team of University of Iowa Health Care researchers has launched an important clinical trial of a novel therapeutic that may eventually lead to new treatments for men diagnosed with prostate cancer. view more (2006-10-16)
First human gets new antibody aimed at rabies virus
MassBiologics of the University of Massachusetts Medical School today announced the beginning of a Phase 1 clinical trial, testing the safety and activity of a human monoclonal antibody (MAB) developed to neutralize the rabies virus. view more (2009-10-01)
Minimally invasive device shows promise in treating female urinary incontinence
A minimally invasive device for treating recurrent stress urinary incontinence in women has been shown to be safe and effective in early clinical trials and is now under review by the U.S. Food and Drug Administration (FDA). view more (2007-05-23)
Does green tea prevent cancer? Evidence continues to brew, but questions remain
Although scientists are reluctant to officially endorse green tea as a cancer prevention method, evidence continues to grow about its protective effects, including results of a new study published in Cancer Prevention Research, a journal of the American Association for Cancer Research, which suggests some reduction in oral cancer. view more (2009-11-05)
Researchers at Pulmonary Associates to study airway bypass procedure for severe emphysema
Researchers at Pulmonary Associates today announced the start of the EASE (Exhale Airway Stents for Emphysema) Trial, an international, multi-center clinical trial to explore an investigational treatment that may offer a new, minimally invasive option for those suffering with advanced widespread emphysema. view more (2008-02-12)
Scottsdale Healthcare-TGen clinical trial results signal advances against skin cancer
Analyses of clinical trial results published today in the New England Journal of Medicine (NEJM) shows a potential new investigational therapy for advanced and metastatic basal cell skin cancer. view more (2009-09-03)
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