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Cancer drug is no different in effectiveness as gold standard treatment for macular degeneration
Investigators from Boston University School of Medicine (BUSM) and the VA Boston Healthcare System have shown, at 6 months in a small group of patients, that there is no difference in efficacy between Bevacizumab (Avastin) and Ranibizumab (Lucentis) for the treatment of age-related macular degeneration (AMD). view more (2009-10-12)
First ever study predicts outcome for limb-threatening infections in diabetes
Researchers from the University of Washington, Rosalind Franklin University of Medicine and Science, Merck Laboratories, and Mount Sinai School of Medicine have released a study suggesting that specific laboratory and clinical tests can predict outcome of antibiotic therapy for infections in persons with diabetes. view more (2007-04-18)
First trial of gene therapy for advanced heart failure shows promising results
Phase I results of the first clinical trial of gene therapy for patients with advanced heart failure show the approach to be promising, with improvements in several measures of the condition's severity. view more (2008-11-11)
Nexavar shown to significantly extend survival for patients with advanced liver cancer
Bayer Pharmaceuticals Corporation (NYSE: BAY) and Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) today announced that an independent data monitoring committee (DMC) has reviewed the safety and efficacy data from the companies' pivotal Phase 3 trial in patients with advanced hepatocellular carcinoma (HCC), or primary liver cancer. view more (2007-02-13)
New stem cell research unlocks unknown therapies
"Stem cell research and regenerative medicine are in an extremely exciting phase right now. We are gaining knowledge very fast and many companies are being formed and are starting clinical trials in different areas," says Dr Jonas Frisén. view more (2009-05-22)
Intake of dietary copper helps Alzheimer's patients
As one of the services for patients with Alzheimer's disease, the Department of Psychiatry at the Saarland University Medical Center offers participation in a clinical phase II trial. This clinical trial aims to elucidate a potential beneficial effect of copper orotate (an organic copper salt), which is given together with a standard... view more... (2005-10-04)
U of M begins nation's first clinical trial using T-reg cells from cord blood in leukemia treatment
University of Minnesota researchers have initiated a ground breaking clinical trial to determine the optimal dose and safety of T regulatory cells (T-regs) to decrease the risk of immune reactions common in patients undergoing blood and marrow transplantation. view more (2007-09-06)
Day-care services could be option for pregnancy complications (pp 1089, 1104)
Research from Australia in this week's issue of THE LANCET highlights how day-care services could offer some benefits over hospital admission for women with pregnancy complications. Day care is increasingly being used for complications of pregnancy, despite little evidence that it is effective. Deborah Turnbull from the University of Adelaide,... view more... (2004-03-31)
Concern over the future of clinical trials
A new European directive has prompted concerns over the future of publicly funded clinical trials in the United Kingdom, according to an editorial in this week's BMJ. view more (2004-01-29)
Study Emphasizes Importance of Women in Cardiac Research
A recent trial, published in the Journal of Cardiovascular Electrophysiology, shows that women with abnormal heart rhythms benefit from implantable cardioverter defibrillators (ICDs) as much as men, stressing the importance of including females in future research. Previous studies have raised the concern of possible gender bias, in favor of men,... view more... (2004-11-18)
Mentally fatigued persons switch to automatic pilot
Mentally fatigued trial subjects search less systematically for solutions than fit colleagues. Such fatigued persons switch to an automatic pilot approach even when this repeatedly leads to the same mistakes. Psychologists from the University of Amsterdam studied how purposefully mentally fatigued persons conducted themselves. Healthy persons and... view more... (2002-05-23)
Drug fends off kidney cancer progression
New data from an international, multicenter Phase III clinical trial has found that the experimental targeted therapy everolimus (RAD001) significantly delays cancer progression in patients with metastatic kidney cancer whose disease had worsened on other treatments. view more (2008-05-19)
ESC Congress 2004: New findings from ground-breaking PROVE IT-TIMI 22 clinical trial
Study Finds Antibiotics Do Not Prevent Heart Attacks view more (2004-08-30)
Studies show novel device may enhance chemotherapy treatment in brain tumors
NovoCure Ltd. presented results yesterday evaluating the Novo-TTF device in vitro and in a pilot clinical trial that showed the device enhanced the efficacy of standard chemotherapy (temozolomide) treatment in newly-diagnosed glioblastoma multiforme (GBM) patients. view more (2008-11-25)
Increased glucose level is a strong risk factor for colorectal cancer
Diabetes is a very common illness that affects more than 20 million people in the U.S. and it is estimated an additional 54 million Americans have pre-diabetes, a condition that occurs when a person's blood glucose levels are higher than normal but not high enough for a diagnosis of type 2 diabetes. view more (2007-11-02)
Pulmonary artery catheter use neutral for patient outcomes
The use of a pulmonary artery catheter (PAC) - a device used for more than 30 years to assess cardiovascular health and to help guide the treatment of critically ill patients - does not appear to improve outcomes nor confer added risks to patients. view more (2005-10-05)
Shrinkage of prostate led to overestimation of cancer risk in trial
Reanalysis of data from the first long-term randomized trial of a chemopreventive agent for prostate cancer shows that the excess prevalence of high-grade prostate cancer in the drug-treated group may be attributable to shrinkage of the prostate at the time of biopsy. view more (2007-09-13)
Study of drug therapy for compulsive buying yields a puzzle, Stanford researcher says
Researchers at the Stanford University School of Medicine say they are puzzled by findings from their new study indicating that an antidepressant, which previously showed promise in treating a behavioral disorder known as compulsive buying, did not result in a sustained benefit for the patients who took it. view more (2007-03-14)
Targeted therapy shows significant benefits over standard treatment for advanced kidney cancer
According to a new study, the drug sunitinib malate (Sutent®) is more effective than the current standard cytokine treatment given as an initial therapy for patients with advanced kidney cancer, also known as metastatic renal cell carcinoma (mRCC). view more (2006-06-05)
Findings released from 1 of the largest percutaneous coronary intervention trials ever
A study led by Gregg W. Stone, M.D., professor of medicine at Columbia University Medical Center/NewYork-Presbyterian and chairman of the Cardiovascular Research Foundation, has shown that heart attack patients who were administered the direct thrombin inhibitor bivalirudin during primary angioplasty had a reduced rate of adverse clinical events,... view more... (2008-05-27)
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