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Enrollment in cancer trials not linked to better health outcomes (p 263)
The widely held view that people with cancer who participate in clinical trials have better treatment outcomes is disputed by US authors of a study in this week's issue of THE LANCET. Less than 5% of adults with cancer are enrolled into clinical trials. Steven Joffe from the Dana-Farber Cancer Institute, Boston, USA, and colleagues reviewed 26... view more... (2004-01-21)
Concern over the future of clinical trials
A new European directive has prompted concerns over the future of publicly funded clinical trials in the United Kingdom, according to an editorial in this week's BMJ. view more (2004-01-29)
South Asian people are under-represented in clinical trials
People of South Asian ethnic origin are underrepresented in clinical trials, finds a study in this week’s BMJ. view more (2003-06-04)
How can we secure the future of medical research?
Clinical research in Britain is in decline. This week's BMJ reveals that the number of non-commercial trials has fallen in recent years, while a summary of a new report from the Academy of Medical Sciences sets out what is needed to revitalise clinical research. view more (2003-10-29)
EDCTP appoints Interim Executive Director
On 10 December 2004 the governing body of the EDCTP (European & Developing Countries Clinical Trials Partnership), the EEIG-Assembly, appointed Prof. Bernt Lindtj'¸rn as Interim Executive Director of EDCTP. He will assume this position on December 20 for a period of up to six months until a new Executive Director has been appointed. Prof.... view more... (2004-12-21)
Undisclosed payments to doctors recruiting trial patients is unethical
Doctors are often paid to recruit patients to clinical trials sponsored by pharmaceutical companies, yet such payments are often not disclosed to the patients. Researchers in this week`s BMJ argue that this practice is unethical and damages efforts to involve patients more fully in clinical trials. Over the years, payments have soared to thousands... view more... (2002-07-03)
Current Controlled Trials' numbering scheme is adopted by CHIR
Dr. Alan Bernstein, President of the Canadian Institutes of Health Research (CIHR), announced today a new randomized controlled trial policy that will require all CIHR funded clinical trials to register with an International Standard Randomised Controlled Trial Number (ISRCTN). The goal of the policy is to help ensure clinicians, researchers,... view more... (2004-07-23)
Curry-cure? Spicing up the effectiveness of a potential disease-fighter
Scientists are reporting development of a nano-size capsule that boosts the body's uptake of curcumin, an ingredient in yellow curry now being evaluated in clinical trials for treatment of several diseases. view more (2009-11-05)
Paediatric research should take centre stage (pp 732, 803)
An editorial in this week's issue of THE LANCET comments on the recent UK Government's announcement of a new initiative to encourage the development of more medicines designed specifically for use in children. "Off-label" use is common in paediatrics, which can mean that drugs have not been tested at all in children or in a particular... view more... (2004-08-25)
Negative Newspaper Articles about Clinical Trials Decrease Public Willingness to Participate, Study Finds
A University of Missouri-Columbia study has found that newspapers' front page and section stories about clinical trials are overwhelmingly negative and that exposure to these stories may decrease people's willingness to participate in medical trials. view more (2007-03-21)
Cancer treatments in phase 3 trials successful up to half of the time
About one-fourth to one-half of new cancer treatments that reach assessment in phase 3 randomized clinical trials are eventually proven successful, according to a report in the March 24 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. view more (2008-03-25)
Funding source has impact on conclusions of clinical trials
Author conclusions in clinical trials funded by for profit organisations are more likely to favour experimental intervention than trials funded by not for profit organisations reveals a study in this week's BMJ. As the BMJ is one of a few journals which requires authors to declare funding and competing interests, the researchers used 159 trials... view more... (2002-07-31)
New stem cell research unlocks unknown therapies
"Stem cell research and regenerative medicine are in an extremely exciting phase right now. We are gaining knowledge very fast and many companies are being formed and are starting clinical trials in different areas," says Dr Jonas Frisén. view more (2009-05-22)
Drugs may not delay onset of dementia; and more
Researchers have examined the evidence in favour of giving people considered to be close to developing dementia the drugs that are most commonly used to treat the condition itself. view more (2007-11-27)
Science commentary stresses need for collaboration at local level in HIV-prevention studies
Clinical trials of drugs intended to prevent HIV infection in high-risk populations must be developed and carried out in close collaboration with the local communities and national governments of the countries in which they are conducted, according to 18 international leaders in HIV prevention writing in the current (Sept. 30, 2005) issue of... view more... (2005-10-03)
Government money for multiple sclerosis patients could be better spent
The National Institute for Clinical Excellence (NICE) has announced that neither interferon beta nor glatiramer can be recommended for multiple sclerosis in the NHS. However, the UK government plans to make these drugs available through a risk sharing scheme, despite limited evidence of clinical and cost effectiveness. Researchers in this week's... view more... (2003-02-12)
Health of independent clinical trials in danger, scientist warns
European Union legislation due to take effect next year could have a disastrous effect on non-commercial clinical trials, said a leading cancer researcher today. Speaking at ECCO 12 - The European Cancer Conference in Copenhagen, Professor Fran'§oise Meunier, Director General of the EORTC1 Brussels, Belgium, told a news briefing that the new... view more... (2003-09-22)
International heart and sports medicine experts call for cardiovascular screening programme for athletes
International heart and sports medicine experts have called for a Europe-wide cardiovascular screening programme for all young athletes before they are allowed to take part in competitive athletics. view more (2005-01-30)
New evidence for homeopathy
Two new studies conclude that a review which claimed that homeopathy is just a placebo, published in The Lancet, was seriously flawed. view more (2008-11-04)
Aspirin -- just for men?
First it was an apple, now it is an aspirin a day that may keep the doctor away. Aspirin has become standard for heart attack prevention, but research published in the online open access journal BMC Medicine suggests that this may really be a man's drug. view more (2007-10-18)
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