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Novel cancer vaccine to be manufactured from live bacterium
Cobra Biomanufacturing signs long-term supply agreement to manufacture active ingredient for Advaxis' novel cancer treatment Keele, UK: Cobra Biomanufacturing Plc, the International manufacturer of biopharmaceuticals, today announced an agreement with Advaxis, Inc. to supply clinical trials and, potentially, commercial supplies of the active... view more... (2003-08-04)

Cancer study finds adolescents don't get same access to latest treatments as younger patients
The overall survival rate from cancer now is lower in older adolescents and young adults with cancer than in younger children, in part because of a lack of access to clinical trials nationally for the older age group.   view more (2008-01-16)

Over the counter cough medicines may be an unnecessary expense
There is little evidence for or against the effectiveness of over the counter cough medicines for adults, and they may be an unnecessary expense, finds a study in this week's BMJ. Researchers at the University of Bristol reviewed 15 trials, involving over 2,000 patients, that compared oral over the counter cough medicines with placebo in adults... view more... (2002-02-06)

Why are so few HIV/AIDS trials conducted in Africa?
People in sub-Saharan Africa carry the heaviest burden of HIV and AIDS, yet very few trials have been conducted on the African continent over the past two decades, say researchers in this week's BMJ.   view more (2005-09-30)

Teenagers with cancer are missing out on vital services says UK politician
Dr Ian Gibson MP, Chair of the All Party Working Group on Cancer, has today called on the Government to make further provisions for teenagers with cancer, who are currently falling far behind children and adults when it comes to cancer services. Speaking at a news briefing at Teenage Cancer Trust's Third International Conference on Cancer and the... view more... (2004-02-29)

Doctors awarded international prize for research leading to new treatment in rheumatoid arthritis
The Crafoord Prize is awarded annually by the Royal Swedish Academy of Sciences for research in areas not covered by the Nobel prizes, which the academy also awards. The prize consists of a gold medal to each prize-winner and $500,000 (approximately £300,000) to be divided between them. It will be awarded on 18 September 2000 at the Royal... view more... (2000-01-20)

Hospitals that participate in clinical trials may provide better patient care
Hospitals that participate in clinical trials appear to provide better care for patients with heart attacks or other acute heart events and have lower death rates than hospitals that do not participate in clinical trials, according to a report in the March 24 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.   view more (2008-03-25)

New Canadian study demonstrates clear survival benefit of breast cancer treatment in trials
Hamburg, Germany: A new Canadian study has found that breast cancer patients who were treated according to accepted standards of care or who took part in clinical trials were from 30% to 60% less likely to die from any cause during a seven-year follow up period. Lead researcher Dr Nicole Hébert-Croteau told the 4th European Breast Cancer... view more... (2004-03-17)

Neonatal trials - asking the right questions
Gaining consent from parents on behalf of their children for neonatal trials - where new treatments are tested on new-born, ill babies - is often asked for and given inappropriately, Leeds research has shown. Dr Su Mason from the clinical trials and research unit interviewed 200 parents from nine European countries and found that in two-thirds of... view more... (2004-02-23)

Medical management of another condition may not lead to early cancer diagnosis
Being in regular contact with healthcare providers because of a chronic illness such as diabetes or heart disease doesn't necessarily mean a person is more likely to have a cancer detected early.   view more (2007-06-04)

Greater transparency for clinical trials
Launch of the first international clinical trial numbering scheme Current Controlled Trials Ltd today announced the launch of the International Standard Randomised Controlled Trial Number (ISRCTN) Register. The ISRCTN Register represents the first online service that provides unique numbers to randomised controlled trials in all areas of health... view more... (2003-05-16)

Developing better methods of 'blinding' doctors and patients in clinical trials
When trials are carried out to assess the effectiveness of a drug, it is an important to have a control group of patients who are not given the drug.   view more (2006-10-31)

Patients should be more involved in the clinical trial process
Patients should be treated as participants rather than subjects during clinical trials, suggest researchers in this week’s BMJ.   view more (2002-12-04)

Cystic fibrosis clinical study patients show less lung function decline
Although cystic fibrosis patients in clinical trials had more severe illness, worse lung function, a lower weight level and more respiratory infection than non-participants, their involvement in research studies resulted in less lung function decline over a 7-year period.   view more (2006-01-03)

Detecting bias in the reporting of clinical trials
A study by researchers at the University of Leicester has revealed new ways to spot whether medical research has hidden biases.   view more (2009-08-19)

Study suggests reliability of cognitive assessment tool varies widely
The Netherlands and Sun City, AZ, USA -- A study published in the November issue of the Journal of Alzheimer's Disease suggests the reliability of the Alzheimer's Disease Assessment Scale - Cognitive may vary and possess the ability to affect clinical trial outcomes.   view more (2008-11-25)

Optimal adjuvant radiation therapy associated with improved survival, meta-analysis shows
A new analysis of adjuvant radiation therapy in women with breast cancer following mastectomy is associated with better survival as measured at 10 years when appropriate doses and fields of radiation are used.   view more (2006-01-04)

Registration of randomised controlled trials: Demand for openness, transparency and public access to the results of clinical trials turned down by the European Commission
The recommendations made by the European Science Foundation (ESF) and its European Medical Research Council Committee (EMRC) on public access to clinical trials data can not be met through the confidential register of drug trials being established through the European Council Directive. ESF/EMRC now appeal to its member organisations to establish... view more... (2003-02-11)

Controversies Regarding Ovarian Cancer Treatments Addressed
Trials have raised questions on the current management and standard of care for advanced ovarian cancer (AOC). These controversies highlight implications for future clinical research and policy-making, as reviewed in an article published in the International Journal of Gynecological Cancer.   view more (2004-11-10)

Pneumococcal vaccine does not appear to protect against pneumonia
Commonly used pneumococcal polysaccharide vaccines do not appear to be effective for preventing pneumonia.   view more (2009-01-06)
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