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Medical Journals Are An Extension of the Marketing Arm of Pharmaceutical Companies, says Former Editor
"Medical journals are an extension of the marketing arm of pharmaceutical companies," argues Richard Smith, former editor of the BMJ and now Chief Executive of UnitedHealth Europe, in a provocative essay published in the open access international health journal PLoS Medicine (www.plosmedicine.org). view more (2005-05-12)
JUSTIFICATION FOR USE OF ELECTROCONVULSIVE THERAPY TO TREAT DEPRESSION (p 799)
Authors of a systematic review in this week's issue of THE LANCET conclude that there is an evidence base to support the use of electroconvulsive therapy (ECT) in the treatment of depression. They conclude that it may be better than drug therapy to treat short-term depressive illness, although ECT use is associated with impaired cognitive ability... view more... (2003-03-05)
Positive results more likely from industry-funded breast cancer trials
Industry-funded studies of breast cancer therapies are more likely to report positive results than non-pharmaceutical funded studies, researchers from the University of North Carolina at Chapel Hill and the Dana Farber Cancer Institute have found. view more (2007-02-26)
More patients needed in clinical trials to find treatment for heart condition linked to certain strokes
The American Heart Association and the American College of Cardiology are calling on doctors to enroll more patients in clinical trials for catheter-based closure of patent foramen ovale (PFO), a condition caused when an opening between the two chambers of the heart fails to close at birth. view more (2009-05-12)
How to treat gastroesophageal adenocarcinom patients?
Gastroesophageal adenocarcinomas have a poor prognosis. However, numerous randomized clinical trials (RCT) have evaluated, and continue to evaluate, the survival benefit of various treatment regimens. view more (2008-09-18)
Neurotherapeutics presents special issue on new treatments for Alzheimer's disease
The editors of Neurotherapeutics are pleased and proud to announce their July issue, devoted to "Novel Therapeutics for Alzheimer's Disease." view more (2008-07-25)
University of Nottingham to launch £300,000 centre for research into gastrointestinal diseases
A new £305,472 research centre that will bring together cutting-edge expertise in gastrointestinal diseases, including irritable bowel syndrome (IBS), Crohn's disease, the bacteria helicobacter pylori and cancer, is to be launched at The University of Nottingham. The new Wolfson Digestive Diseases Centre, substantially funded with a grant... view more... (2003-06-12)
The Lancet Neurology October Issue
Mental health bill or public order-cause for concern Can we predict whether an individual with a severe personality disorder will commit murder? Should compulsory treatment in the community be introduced? In a draft mental health bill, which was under consultation until September 16, the UK government has proposed a number of changes that have... view more... (2002-09-13)
European Commissioner Busquin Presents Clinical Trials Programme To African Health Ministers
At the WHO conference in Johannesburg on 1 September, European Research Commissioner Philippe Busquin will present the Europe-Developing Countries Clinical Trials Partnership (EDCTP) to the Ministers for Health of 46 African States. EDCTP aims to combat HIV/AIDS, malaria and tuberculosis with a EUR600 million budget to which the European Union has... view more... (2003-09-01)
Antiepileptic Drug Developed At Hebrew University To Undergo Phase Three Clinical Trials Under New Agreement
The new antiepileptic drug valrocemide, developed at the Hebrew University of Jerusalem by Meir Bialer, the David Eisenberg Professor of Pharmacy, will undergo phase three clinical trials in the U.S. under a new agreement between Teva Pharmaceutical Industries of Israel and Acorda Therapeutics of the U.S. Teva acquired the rights to the drug from... view more... (2003-10-02)
Pulmonary artery catheter use neutral for patient outcomes
The use of a pulmonary artery catheter (PAC) - a device used for more than 30 years to assess cardiovascular health and to help guide the treatment of critically ill patients - does not appear to improve outcomes nor confer added risks to patients. view more (2005-10-05)
Some nonhormonal therapies may offer relief from hot flashes, but with possible adverse effects
A meta-analysis of previously published studies examining the use of nonhormonal therapies for treating menopausal hot flashes finds that some therapies are effective, but less so than estrogen, and have possible adverse effects that may restrict their use. view more (2006-05-03)
New EC Directive Threatens Life-Saving Trials
Europeans should wake up to the threat of a new European Directive, which will make many potentially life-saving studies performed in emergency medicine impossible, warn researchers in this week's BMJ. The Directive could stop trials of treatments for patients rendered suddenly mentally incapacitated by, for example, cardiac arrest, head injury,... view more... (2002-07-24)
Promising early evidence of the superior benefits of drug therapy for diabetic eye disease
A JDRF collaboration between Johns Hopkins researchers and Genentech has shown that a drug for the treatment of diabetic eye disease has performed better in clinical trials than the current standard treatment using laser surgery. view more (2008-04-30)
Limitations of Current Evaluation Techniques for the Cost-Effectiveness of Treatments for Parkinson's Disease
Parkinson's disease (PD) is one of the most common neurodegenerative disorders. Pharmaceutical and surgical therapies for PD are available and can alleviate the symptoms and complications. Unfortunately, despite these therapies, the disease relentlessly progresses. A new study in the journal Value in Health presents a detailed overview of the... view more... (2004-11-10)
Why were the HIV prevention trials in commercial sex workers abandoned?
One promising approach to help stem the global HIV epidemic is to give commercial sex workers an HIV medication (such as the drug tenofovir) before they have high risk sex in the hope of reducing their chances of becoming infected, an approach called "pre-exposure prophylaxis" (PREP). view more (2005-07-19)
Preventing tuberculosis reactivation
Tuberculosis (TB) is the leading cause of death due to infectious disease in the world today. It is estimated that 2 billion people are currently infected, and although most people have latent infection, reactivation can occur. view more (2007-10-18)
Vitamin E trials 'fatally flawed'
Generations of studies on vitamin E may be largely meaningless, scientists say, because new research has demonstrated that the levels of this micronutrient necessary to reduce oxidative stress are far higher than those that have been commonly used in clinical trials. view more (2007-09-24)
Combining therapies can improve survival for early-stage breast cancer patients
Patients with early-stage breast cancer who are treated with both chemotherapy and tamoxifen have a higher survival rate than patients who receive only tamoxifen. view more (2007-04-04)
Widely-Used Treatment For Head Injuries Found To Be Harmful (pp 1291, 1321)
The use of anti-inflammatory drugs to treat patients with severe head injuries-common practice worldwide for the past 30 years-is actually dangerous and associated with around a 20% increase in death within two weeks of hospital admission, conclude authors of an international study in this week's issue of THE LANCET. view more (2004-10-06)
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