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Inducing Melanoma for Cancer Vaccine Development
Cancer vaccines are being investigated in early-phase clinical trials around the world, with many of those trials recruiting patients with melanoma. view more (2006-03-28)
Probiotics may prevent antibiotic associated diarrhoea
Probiotics (microbes that protect their host and can prevent disease) can prevent diarrhoea associated with the use of antibiotics, finds a study in this week’s BMJ. view more (2002-06-05)
Dasatinib, Nilotinib show strong early results as frontline therapy for chronic myelogenous leukemia
Two drugs approved for use as second line therapy for chronic myelogenous leukemia are showing promising results as frontline therapy for newly diagnosed patients in two clinical trials, research teams led by scientists at The University of Texas M. D. Anderson Cancer Center report at the 49th annual meeting of the American Society of Hematology. view more (2007-12-10)
Most ongoing diabetes trials do not include outcomes important to patients
An analysis of ongoing randomized clinical trials (RCTs) in diabetes finds that only about 20 percent have as primary outcomes results that patients consider important, such as illness, pain, effect on function and death, according to a study in the June 4 issue of JAMA. view more (2008-06-04)
Study sets treatment standard for elderly with colon cancer
One of the newest and most potent chemotherapies for colon cancer is as safe and effective for the elderly as it is for younger patients, based on a University of North Carolina at Chapel Hill-led data review. view more (2006-02-13)
Drugs used for cancer-associated anemia linked with increased risk of blood clots, death
Treating anemia with a class of drugs known as erythropoiesis-stimulating agents (ESAs) is associated with an increased risk of venous thromboembolism (blood clots in the deep veins of the legs or in the lungs) and death among patients with cancer. view more (2008-02-27)
Academic clinical research is under threat from the EU
Embargo: 09.00hrs CET Thursday 25 September 2003 Copenhagen, Denmark: New therapies for hard-to-treat or rare cancers might never be developed and patients would continue to suffer and die unless problems with the proposed EU directive[1] on clinical trials are resolved, a leading cancer expert warned today in a news briefing at ECCO12 - The... view more... (2003-09-22)
Ethical committee members have different views on how to evaluate clinical trials
Members of ethical committees, which decide whether or not to grant approval for phase two clinical trials, infrequently use systematic methods when weighing up the risks and benefits of a study, according to research published today (Thursday 1 August) in the Annals of Oncology, the journal of the European Society for Medical Oncology.* A team of... view more... (2002-07-29)
Daisies lead scientists down path to new leukemia drug
A new, easily ingested form of a compound that has already shown it can attack the roots of leukemia in laboratory studies is moving into human clinical trials, according to a new article by University of Rochester investigators in the journal, Blood. view more (2007-10-03)
Findings challenge common practice regarding glucose control for critically ill patients
An analysis of randomized trials indicates that for critically ill adults, tight glucose control is not associated with a significantly reduced risk of death in the hospital, but is associated with an increased risk of hypoglycemia, calling into question the recommendation by many professional societies for tight glucose control for these patients. view more (2008-08-27)
University of Manchester awarded £826k for brain science and mental health research
The University of Manchester's Faculty of Medical and Health Sciences has been awarded £826k by the Medical Research Council (MRC) and Department of Health (DH). The award is part of a £5.3m package, to fund research projects into brain science and build increased capacity for clinical trials of new treatments. view more (2005-03-07)
SSX, a new family of cancer vaccine targets
Scientists from the Cancer Vaccine Collaborative (CVC) have discovered that the cancer-specific protein, SSX-2, induces a spontaneous immunological reaction against cancer cells in melanoma patients, offering a new target for the development of a therapeutic melanoma vaccine. SSX-2 is the prototype of the SSX family, and is part of a larger group... view more... (2004-04-01)
Advances in lung cancer research announced at conference
Dr. Glen Weiss of the Translational Genomics Research Institute (TGen) and Scottsdale Healthcare this week announced two significant advances in treating lung cancer at an international cancer research conference. view more (2009-08-10)
Frog molecule could provide drug treatment for brain tumours
Known as Amphinase, the molecule recognises the sugary coating found on a tumour cell and binds to its surface before invading the cell and inactivating the RNA it contains, causing the tumour to die. view more (2007-06-27)
Drug rescues memory lost to Alzheimer's disease
A drug similar to one used in clinical trials for treatment of rheumatoid arthritis and psoriasis has been found to rescue memory in mice exhibiting Alzheimer's symptoms. view more (2009-07-15)
Underutilized treatment for advanced ovarian cancer found to significantly improve survival
According to a study published in the January 5 issue of the New England Journal of Medicine, women with Stage III ovarian cancer given a combination of intravenous (IV) and intra-abdominal chemotherapy, following the successful surgical removal of tumors, experienced a median survival time 16 months longer than women who received IV chemotherapy... view more... (2006-01-05)
Stanford doctors spotlight fatal flaw in multiple sclerosis drug trial
When Anita Louise Smith enrolled in an experimental drug trial in 2002 in Colorado, she had a diagnosis of multiple sclerosis but no symptoms and was looking to reduce the chances of being ravaged by the disease. Last year, she died at the age of 46 from an infection linked to the drug. view more (2006-03-03)
Footrot vaccine closer than ever
Monash University scientists have started clinical trials to find a successful vaccine against footrot in sheep. view more (2008-07-02)
Chemistry & Industry - 6 May Issue
NEWS Cancer vaccine from patient’s own blood (page 4) A novel cancer vaccine made from patient’s own blood is in clinical trials in the US. In phase II clinical trials, a 60% reduction in median-tumour growth was observed and, in some cases, tumours stopped growing altogether. view more (2002-05-01)
Effectiveness of first renin inhibitor drug for treating hypertension is limited
Hypertension is a serious condition affecting millions. Currently there are seven classes of drugs used to reduce blood pressure. view more (2007-05-10)
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